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P74309

- ALF1_SYNY3

UniProt

P74309 - ALF1_SYNY3

Protein

Fructose-bisphosphate aldolase class 1

Gene

fda

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 89 (01 Oct 2014)
      Sequence version 1 (01 Feb 1997)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei181 – 1811Proton acceptorBy similarity
    Active sitei218 – 2181Schiff-base intermediate with dihydroxyacetone-PBy similarity

    GO - Molecular functioni

    1. fructose-bisphosphate aldolase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Lyase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    Schiff base

    Enzyme and pathway databases

    SABIO-RKP74309.
    UniPathwayiUPA00109; UER00183.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Fructose-bisphosphate aldolase class 1 (EC:4.1.2.13)
    Alternative name(s):
    Fructose-bisphosphate aldolase class I
    Short name:
    FBP aldolase
    Gene namesi
    Name:fda
    Synonyms:fbaB
    Ordered Locus Names:slr0943
    OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
    Taxonomic identifieri1111708 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
    ProteomesiUP000001425: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 300300Fructose-bisphosphate aldolase class 1PRO_0000216913Add
    BLAST

    Proteomic databases

    PaxDbiP74309.

    Interactioni

    Protein-protein interaction databases

    IntActiP74309. 1 interaction.
    STRINGi1148.slr0943.

    Structurei

    3D structure databases

    ProteinModelPortaliP74309.
    SMRiP74309. Positions 6-300.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG3588.
    HOGENOMiHOG000073502.
    KOiK01623.
    OMAiYTGDYLA.
    OrthoDBiEOG6M6JJT.
    PhylomeDBiP74309.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00729. FBP_aldolase_1.
    InterProiIPR013785. Aldolase_TIM.
    IPR000741. FBA_I.
    IPR023014. FBA_I_Gram+-type.
    [Graphical view]
    PfamiPF00274. Glycolytic. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P74309-1 [UniParc]FASTAAdd to Basket

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    MMTLEPNQEQ LKKMKSHPGF IAALDQSGGS TPGALADYGI EPNTYSGDDQ    50
    MFALVHQMRT RIMTSPGFTG DRILAAILFE DTMNREVDGE PTANYLWQNK 100
    QIVPILKVDK GLAQEKDGSQ LMKPIPQLDS LLMKAKKKGI FGTKMRSFIK 150
    HANPAGIEAI VDQQFELAQQ IIAAGLVPII EPEVDIHCSE KAQAEALLKQ 200
    AMLKHLNQLP KGQWVMLKLT LPEQDNLYSN CIEHANVLRV VALSGGYSQA 250
    EANERLSRNH GVIASFSRAL TEGLTAQQTD AEFNTMLDES IEKIYQASIT 300
    Length:300
    Mass (Da):33,149
    Last modified:February 1, 1997 - v1
    Checksum:iEDAE4D24F58FE667
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000022 Genomic DNA. Translation: BAA18403.1.
    PIRiS76144.
    RefSeqiNP_441723.1. NC_000911.1.
    YP_005651782.1. NC_017277.1.
    YP_007451605.1. NC_020286.1.

    Genome annotation databases

    EnsemblBacteriaiBAA18403; BAA18403; BAA18403.
    GeneIDi952985.
    KEGGisyn:slr0943.
    syy:SYNGTS_1829.
    syz:MYO_118460.
    PATRICi23840928. VBISynSp132158_2018.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000022 Genomic DNA. Translation: BAA18403.1 .
    PIRi S76144.
    RefSeqi NP_441723.1. NC_000911.1.
    YP_005651782.1. NC_017277.1.
    YP_007451605.1. NC_020286.1.

    3D structure databases

    ProteinModelPortali P74309.
    SMRi P74309. Positions 6-300.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P74309. 1 interaction.
    STRINGi 1148.slr0943.

    Proteomic databases

    PaxDbi P74309.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAA18403 ; BAA18403 ; BAA18403 .
    GeneIDi 952985.
    KEGGi syn:slr0943.
    syy:SYNGTS_1829.
    syz:MYO_118460.
    PATRICi 23840928. VBISynSp132158_2018.

    Phylogenomic databases

    eggNOGi COG3588.
    HOGENOMi HOG000073502.
    KOi K01623.
    OMAi YTGDYLA.
    OrthoDBi EOG6M6JJT.
    PhylomeDBi P74309.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00183 .
    SABIO-RK P74309.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00729. FBP_aldolase_1.
    InterProi IPR013785. Aldolase_TIM.
    IPR000741. FBA_I.
    IPR023014. FBA_I_Gram+-type.
    [Graphical view ]
    Pfami PF00274. Glycolytic. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
      Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
      , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
      DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PCC 6803 / Kazusa.

    Entry informationi

    Entry nameiALF1_SYNY3
    AccessioniPrimary (citable) accession number: P74309
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 15, 1998
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 89 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families
    3. Synechocystis PCC 6803
      Synechocystis (strain PCC 6803): entries and gene names

    External Data

    Dasty 3