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P74309

- ALF1_SYNY3

UniProt

P74309 - ALF1_SYNY3

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Protein

Fructose-bisphosphate aldolase class 1

Gene
fda, fbaB, slr0943
Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei181 – 1811Proton acceptor By similarity
Active sitei218 – 2181Schiff-base intermediate with dihydroxyacetone-P By similarity

GO - Molecular functioni

  1. fructose-bisphosphate aldolase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

Schiff base

Enzyme and pathway databases

SABIO-RKP74309.
UniPathwayiUPA00109; UER00183.

Names & Taxonomyi

Protein namesi
Recommended name:
Fructose-bisphosphate aldolase class 1 (EC:4.1.2.13)
Alternative name(s):
Fructose-bisphosphate aldolase class I
Short name:
FBP aldolase
Gene namesi
Name:fda
Synonyms:fbaB
Ordered Locus Names:slr0943
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 300300Fructose-bisphosphate aldolase class 1UniRule annotationPRO_0000216913Add
BLAST

Proteomic databases

PaxDbiP74309.

Interactioni

Protein-protein interaction databases

IntActiP74309. 1 interaction.
STRINGi1148.slr0943.

Structurei

3D structure databases

ProteinModelPortaliP74309.
SMRiP74309. Positions 6-300.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG3588.
HOGENOMiHOG000073502.
KOiK01623.
OMAiYTGDYLA.
OrthoDBiEOG6M6JJT.
PhylomeDBiP74309.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00729. FBP_aldolase_1.
InterProiIPR013785. Aldolase_TIM.
IPR000741. FBA_I.
IPR023014. FBA_I_Gram+-type.
[Graphical view]
PfamiPF00274. Glycolytic. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P74309-1 [UniParc]FASTAAdd to Basket

« Hide

MMTLEPNQEQ LKKMKSHPGF IAALDQSGGS TPGALADYGI EPNTYSGDDQ    50
MFALVHQMRT RIMTSPGFTG DRILAAILFE DTMNREVDGE PTANYLWQNK 100
QIVPILKVDK GLAQEKDGSQ LMKPIPQLDS LLMKAKKKGI FGTKMRSFIK 150
HANPAGIEAI VDQQFELAQQ IIAAGLVPII EPEVDIHCSE KAQAEALLKQ 200
AMLKHLNQLP KGQWVMLKLT LPEQDNLYSN CIEHANVLRV VALSGGYSQA 250
EANERLSRNH GVIASFSRAL TEGLTAQQTD AEFNTMLDES IEKIYQASIT 300
Length:300
Mass (Da):33,149
Last modified:February 1, 1997 - v1
Checksum:iEDAE4D24F58FE667
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000022 Genomic DNA. Translation: BAA18403.1.
PIRiS76144.
RefSeqiNP_441723.1. NC_000911.1.
YP_005651782.1. NC_017277.1.
YP_007451605.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA18403; BAA18403; BAA18403.
GeneIDi952985.
KEGGisyn:slr0943.
syy:SYNGTS_1829.
syz:MYO_118460.
PATRICi23840928. VBISynSp132158_2018.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000022 Genomic DNA. Translation: BAA18403.1 .
PIRi S76144.
RefSeqi NP_441723.1. NC_000911.1.
YP_005651782.1. NC_017277.1.
YP_007451605.1. NC_020286.1.

3D structure databases

ProteinModelPortali P74309.
SMRi P74309. Positions 6-300.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P74309. 1 interaction.
STRINGi 1148.slr0943.

Proteomic databases

PaxDbi P74309.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA18403 ; BAA18403 ; BAA18403 .
GeneIDi 952985.
KEGGi syn:slr0943.
syy:SYNGTS_1829.
syz:MYO_118460.
PATRICi 23840928. VBISynSp132158_2018.

Phylogenomic databases

eggNOGi COG3588.
HOGENOMi HOG000073502.
KOi K01623.
OMAi YTGDYLA.
OrthoDBi EOG6M6JJT.
PhylomeDBi P74309.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00183 .
SABIO-RK P74309.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00729. FBP_aldolase_1.
InterProi IPR013785. Aldolase_TIM.
IPR000741. FBA_I.
IPR023014. FBA_I_Gram+-type.
[Graphical view ]
Pfami PF00274. Glycolytic. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiALF1_SYNY3
AccessioniPrimary (citable) accession number: P74309
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: February 1, 1997
Last modified: September 3, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
  3. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3

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