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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.By similarity

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.

Cofactori

Mg2+By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei203 – 2031By similarity
Active sitei680 – 6801By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylase (EC:4.1.1.31)
Short name:
PEPC
Short name:
PEPCase
Gene namesi
Name:ppc
Ordered Locus Names:sll0920
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10341034Phosphoenolpyruvate carboxylasePRO_0000166642Add
BLAST

Proteomic databases

PaxDbiP74299.
PRIDEiP74299.

Interactioni

Protein-protein interaction databases

DIPiDIP-48802N.
IntActiP74299. 4 interactions.
STRINGi1148.SYNGTS_1818.

Structurei

3D structure databases

ProteinModelPortaliP74299.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.Curated

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
InParanoidiP74299.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.
PhylomeDBiP74299.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 3 hits.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P74299-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLAVPAFGL STNWSGNGNG SNSEEESVLY QRLKMVEELW ERVLQSECGQ
60 70 80 90 100
ELVDLLTELR LQGTHEAITS EISEEVIMGI TQRIEHLELN DAIRAARAFA
110 120 130 140 150
LYFQLINIVE QHYEQNEQQR NRWEASQETN FYEQAGNEEE MVPPSRLGAS
160 170 180 190 200
TEPLPVGIDQ NELQASVGTF HWLMRELKRL NVPPQHIQNL LDHLDIRLVI
210 220 230 240 250
TAHPTEIVRH TIRRKQRRVD RILRKLDQLQ GSVTGRDWLN TWDAKTAIAQ
260 270 280 290 300
LTEEIRFWWR TDELHQFKPT VLDEVDYSLH YFDEVLFDAV PELSKRLGQA
310 320 330 340 350
IKETFPHLRA PRANFCYFGS WVGGDRDGNP SVTPEVTWQT ACYQRGLVLG
360 370 380 390 400
KYLFSLGELV AILSPSLHWC KVSQELLDSL ERDRIQLPEI YEELSLRYRQ
410 420 430 440 450
EPYRMKLAYV TKRLENTLRR NNRLANPEER QTMITMPAEN HYRTGEELLE
460 470 480 490 500
ELRLIQRNLT ETGLTCLELE NLITQLEVYG FNLAQLDFRQ ESSRHAEAIA
510 520 530 540 550
EIAEYMGVLT TPYEEMAEED KLAWLGVELQ TRRPLIPQEM PFSERTRETI
560 570 580 590 600
ETLRTLRHLQ MEFGVDICQT YIISMTNDAS DVLEVLLLAK EAGLYDPATA
610 620 630 640 650
SNSLRIVPLF ETVEDLKNAP GIMDSLFSLP FYRATLAGSY HSLKELQNQP
660 670 680 690 700
PDYYQIPTTT ALLNPGNLQE IMVGYSDSNK DSGFLSSNWE IHKAQKSLQA
710 720 730 740 750
VAQSHRVILR LFHGRGGSVG RGGGPAYKAI LAQPAGTVDG RIKITEQGEV
760 770 780 790 800
LASKYSLPEL ALYNLETLTT AVIQASLLKS SFDFIEPWNR IMEELACTAR
810 820 830 840 850
RAYRSLIYEE PDFLDFFLTV TPIPEISELQ ISSRPARRKG GKADLSSLRA
860 870 880 890 900
IPWVFSWTQT RFLLPAWYGV GTALKSFVDQ DPVKNMKLLR YFYFKWPFFN
910 920 930 940 950
MVISKVEMTL SKVDLTIASH YVQELSKPED RERFDRLFQQ IKQEYQLTRD
960 970 980 990 1000
FAMEITAHPH LLDGDRSLQR SVLLRNRTIV PLGLLQISLL KRLRQVTQEA
1010 1020 1030
ETSGVRYRRY SKEELLRGAL LTINGIAAGM RNTG
Length:1,034
Mass (Da):118,940
Last modified:February 1, 1997 - v1
Checksum:i76DF6061BAB7235D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA18393.1.
PIRiS76134.
RefSeqiYP_005651771.1. NC_017277.1.
YP_007451595.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA18393; BAA18393; BAA18393.
KEGGisyn:sll0920.
PATRICi23840906. VBISynSp132158_2007.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA18393.1.
PIRiS76134.
RefSeqiYP_005651771.1. NC_017277.1.
YP_007451595.1. NC_020286.1.

3D structure databases

ProteinModelPortaliP74299.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-48802N.
IntActiP74299. 4 interactions.
STRINGi1148.SYNGTS_1818.

Proteomic databases

PaxDbiP74299.
PRIDEiP74299.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA18393; BAA18393; BAA18393.
KEGGisyn:sll0920.
PATRICi23840906. VBISynSp132158_2007.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
InParanoidiP74299.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.
PhylomeDBiP74299.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 3 hits.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiCAPP_SYNY3
AccessioniPrimary (citable) accession number: P74299
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: February 1, 1997
Last modified: June 24, 2015
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.