P74299 (CAPP_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoenolpyruvate carboxylase
Short name=PEPC
Short name=PEPCase
EC=4.1.1.31

Gene names

Name:	ppc
Ordered Locus Names:	sll0920

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]

Taxonomic identifier

1111708 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Synechocystis › Synechocystis sp. PCC 6803

Protein attributes

Sequence length	1034 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595
Catalytic activity	Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the PEPCase type 1 family.

Ontologies

Keywords
Biological process	Carbon dioxide fixation
Ligand	Magnesium
Molecular function	Lyase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	carbon fixation Inferred from electronic annotation. Source: HAMAP oxaloacetate metabolic process Inferred from electronic annotation. Source: HAMAP tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	magnesium ion binding Inferred from electronic annotation. Source: HAMAP phosphoenolpyruvate carboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1034	1034	Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595		PRO_0000166642
Sites
	Active site	203	1	By similarity
	Active site	680	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	P74299 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 76DF6061BAB7235D	FASTA	1,034	118,940
	10 20 30 40 50 60 MNLAVPAFGL STNWSGNGNG SNSEEESVLY QRLKMVEELW ERVLQSECGQ ELVDLLTELR 70 80 90 100 110 120 LQGTHEAITS EISEEVIMGI TQRIEHLELN DAIRAARAFA LYFQLINIVE QHYEQNEQQR 130 140 150 160 170 180 NRWEASQETN FYEQAGNEEE MVPPSRLGAS TEPLPVGIDQ NELQASVGTF HWLMRELKRL 190 200 210 220 230 240 NVPPQHIQNL LDHLDIRLVI TAHPTEIVRH TIRRKQRRVD RILRKLDQLQ GSVTGRDWLN 250 260 270 280 290 300 TWDAKTAIAQ LTEEIRFWWR TDELHQFKPT VLDEVDYSLH YFDEVLFDAV PELSKRLGQA 310 320 330 340 350 360 IKETFPHLRA PRANFCYFGS WVGGDRDGNP SVTPEVTWQT ACYQRGLVLG KYLFSLGELV 370 380 390 400 410 420 AILSPSLHWC KVSQELLDSL ERDRIQLPEI YEELSLRYRQ EPYRMKLAYV TKRLENTLRR 430 440 450 460 470 480 NNRLANPEER QTMITMPAEN HYRTGEELLE ELRLIQRNLT ETGLTCLELE NLITQLEVYG 490 500 510 520 530 540 FNLAQLDFRQ ESSRHAEAIA EIAEYMGVLT TPYEEMAEED KLAWLGVELQ TRRPLIPQEM 550 560 570 580 590 600 PFSERTRETI ETLRTLRHLQ MEFGVDICQT YIISMTNDAS DVLEVLLLAK EAGLYDPATA 610 620 630 640 650 660 SNSLRIVPLF ETVEDLKNAP GIMDSLFSLP FYRATLAGSY HSLKELQNQP PDYYQIPTTT 670 680 690 700 710 720 ALLNPGNLQE IMVGYSDSNK DSGFLSSNWE IHKAQKSLQA VAQSHRVILR LFHGRGGSVG 730 740 750 760 770 780 RGGGPAYKAI LAQPAGTVDG RIKITEQGEV LASKYSLPEL ALYNLETLTT AVIQASLLKS 790 800 810 820 830 840 SFDFIEPWNR IMEELACTAR RAYRSLIYEE PDFLDFFLTV TPIPEISELQ ISSRPARRKG 850 860 870 880 890 900 GKADLSSLRA IPWVFSWTQT RFLLPAWYGV GTALKSFVDQ DPVKNMKLLR YFYFKWPFFN 910 920 930 940 950 960 MVISKVEMTL SKVDLTIASH YVQELSKPED RERFDRLFQQ IKQEYQLTRD FAMEITAHPH 970 980 990 1000 1010 1020 LLDGDRSLQR SVLLRNRTIV PLGLLQISLL KRLRQVTQEA ETSGVRYRRY SKEELLRGAL 1030 LTINGIAAGM RNTG

References

[1]

"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000022 Genomic DNA. Translation: BAA18393.1.
PIR	S76134.
RefSeq	NP_441713.1. NC_000911.1. YP_005651771.1. NC_017277.1. YP_007451595.1. NC_020286.1.
3D structure databases
ProteinModelPortal	P74299.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-48802N.
IntAct	P74299. 4 interactions.
STRING	1148.sll0920.
Proteomic databases
PaxDb	P74299.
PRIDE	P74299.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAA18393; BAA18393; BAA18393.
GeneID	12254426. 14617258. 952999.
KEGG	syn:sll0920. syy:SYNGTS_1818.
PATRIC	23840906. VBISynSp132158_2007.
Phylogenomic databases
eggNOG	COG2352.
HOGENOM	HOG000238647.
KO	K01595.
OMA	AIPWVFG.
ProtClustDB	PRK00009.
Family and domain databases
HAMAP	MF_00595. PEPcase_type1.
InterPro	IPR021135. PEP_COase. IPR018129. PEP_COase_AS. IPR022805. PEP_COase_bac/pln-type. IPR015813. Pyrv/PenolPyrv_Kinase. [Graphical view]
Pfam	PF00311. PEPcase. 1 hit. [Graphical view]
PRINTS	PR00150. PEPCARBXLASE.
SUPFAM	SSF51621. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
PROSITE	PS00781. PEPCASE_1. 1 hit. PS00393. PEPCASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CAPP_SYNY3

Accession

Primary (citable) accession number: P74299

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	February 1, 1997
Last modified:	May 1, 2013
This is version 86 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program