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Protein

Phenylalanine--tRNA ligase beta subunit

Gene

pheT

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).

Cofactori

Mg2+By similarityNote: Binds 2 magnesium ions per tetramer.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi473MagnesiumBy similarity1
Metal bindingi479Magnesium; via carbonyl oxygenBy similarity1
Metal bindingi482MagnesiumBy similarity1
Metal bindingi483MagnesiumBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding
Biological processProtein biosynthesis
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Phenylalanine--tRNA ligase beta subunit (EC:6.1.1.20)
Alternative name(s):
Phenylalanyl-tRNA synthetase beta subunit
Short name:
PheRS
Gene namesi
Name:pheT
Ordered Locus Names:sll1553
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesMerismopediaceaeSynechocystis
Proteomesi
  • UP000001425 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001269741 – 810Phenylalanine--tRNA ligase beta subunitAdd BLAST810

Proteomic databases

PaxDbiP74296
PRIDEiP74296

Interactioni

Subunit structurei

Tetramer of two alpha and two beta subunits.By similarity

Protein-protein interaction databases

IntActiP74296, 4 interactors
STRINGi1148.SYNGTS_1815

Structurei

3D structure databases

ProteinModelPortaliP74296
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 150tRNA-bindingAdd BLAST112
Domaini407 – 495B5Add BLAST89
Domaini716 – 809FDX-ACBAdd BLAST94

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000292087
InParanoidiP74296
KOiK01890
OMAiLTPNRSD
PhylomeDBiP74296

Family and domain databases

CDDicd02796 tRNA_bind_bactPheRS, 1 hit
Gene3Di3.30.70.380, 1 hit
3.50.40.10, 1 hit
HAMAPiMF_00283 Phe_tRNA_synth_beta1, 1 hit
InterProiView protein in InterPro
IPR005146 B3/B4_tRNA-bd
IPR009061 DNA-bd_dom_put_sf
IPR005121 Fdx_antiC-bd
IPR036690 Fdx_antiC-bd_sf
IPR012340 NA-bd_OB-fold
IPR004532 Phe-tRNA-ligase_IIc_bsu
IPR020825 Phe-tRNA_synthase_B3/B4
IPR002547 tRNA-bd_dom
IPR033714 tRNA_bind_bactPheRS
IPR005147 tRNA_synthase_B5-dom
PfamiView protein in Pfam
PF03483 B3_4, 1 hit
PF03484 B5, 1 hit
PF03147 FDX-ACB, 1 hit
PF01588 tRNA_bind, 1 hit
SMARTiView protein in SMART
SM00873 B3_4, 1 hit
SM00874 B5, 1 hit
SM00896 FDX-ACB, 1 hit
SUPFAMiSSF46955 SSF46955, 1 hit
SSF50249 SSF50249, 1 hit
SSF54991 SSF54991, 1 hit
TIGRFAMsiTIGR00472 pheT_bact, 1 hit
PROSITEiView protein in PROSITE
PS51483 B5, 1 hit
PS51447 FDX_ACB, 1 hit
PS50886 TRBD, 1 hit

Sequencei

Sequence statusi: Complete.

P74296-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRISVNWLQS LVELNLSPEE LGELLTIAGL EVEEIEDRRS WAAGVVLGRV
60 70 80 90 100
ISREKHPNAD KLSVCVVDIG TEEPSTIVCG AANVRADILV PVATLGSYLP
110 120 130 140 150
KVDLKIKPAK LRGVKSSGMI CSLAELGLSK ESEGIHIFPD LDLPSGSPVG
160 170 180 190 200
PLLGLDDVIL EISPTANRAD ALSMVGVARE VAALTGGKLS LPEIKAVSVS
210 220 230 240 250
DQDLPISVTE PQACPTYVGT VIRGVKVGPS PDWLQQRLLA AGTRPINNVV
260 270 280 290 300
DVTNYVLLEW GQPLHSFDQD KLQTLVGPEG FALGVRFAEE GEKLITLDDQ
310 320 330 340 350
ERTLQPQNLL VTANDQPVAI AGVMGGAATE VDENTQNIVL ETALFDGVTI
360 370 380 390 400
RKSSKAINLR SESSTRYERG VNRCELEVAL HRAIALMTEL AGGTVVRQGK
410 420 430 440 450
ADQRQDRGEA IINLRLERLQ QLLGKVNTPT GIGNITAEDV ERILTDLGCG
460 470 480 490 500
LTRQSDSDTP VWAVTVPSYR QRDIEREIDL IEEVARLYGY DHFCEQLPSN
510 520 530 540 550
TIAGGLSPSY QAELALREAC RGVGLTEVVH YSLVKPHGSE VMLANPLFAE
560 570 580 590 600
YSALRTNLLD GLITAFANNQ AQNNGALNAF EVGRVFWQNE GDIGEADHLA
610 620 630 640 650
GICGGSQITE GTWPQGGKPQ PMSWYDAKGL LEAIFQRLGA TVTYSGDHQD
660 670 680 690 700
PRLHPGRTAL LSCNGTVLGR FGQLHPQLRR EKGLIDEVYA FEITLTPLYQ
710 720 730 740 750
AMETQILGTP DFRPYSPYPA VARDLALYAP LELTVAELTQ AMVKAGGDLL
760 770 780 790 800
EQVELFDEYR GQSVPAGQRS LAFSLAYRVG DRTLTDADVE PLHNQIREAL
810
TKQFAVSLRS
Length:810
Mass (Da):87,888
Last modified:February 1, 1997 - v1
Checksum:i4D14168774C12BE9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA Translation: BAA18390.1
PIRiS75931

Genome annotation databases

EnsemblBacteriaiBAA18390; BAA18390; BAA18390
KEGGisyn:sll1553

Similar proteinsi

Entry informationi

Entry nameiSYFB_SYNY3
AccessioniPrimary (citable) accession number: P74296
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: May 23, 2018
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families
  3. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

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