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P74163

- PYRB_SYNY3

UniProt

P74163 - PYRB_SYNY3

Protein

Aspartate carbamoyltransferase

Gene

pyrB

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 102 (01 Oct 2014)
      Sequence version 1 (01 Feb 1997)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate.

    Pathwayi

    GO - Molecular functioni

    1. amino acid binding Source: InterPro
    2. aspartate carbamoyltransferase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. 'de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
    2. 'de novo' UMP biosynthetic process Source: UniProtKB-UniPathway
    3. cellular amino acid metabolic process Source: InterPro

    Keywords - Molecular functioni

    Transferase

    Keywords - Biological processi

    Pyrimidine biosynthesis

    Enzyme and pathway databases

    UniPathwayiUPA00070; UER00116.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Aspartate carbamoyltransferase (EC:2.1.3.2)
    Alternative name(s):
    Aspartate transcarbamylase
    Short name:
    ATCase
    Gene namesi
    Name:pyrB
    Ordered Locus Names:slr1476
    OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
    Taxonomic identifieri1111708 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
    ProteomesiUP000001425: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 331331Aspartate carbamoyltransferasePRO_0000113218Add
    BLAST

    Proteomic databases

    PaxDbiP74163.

    Interactioni

    Protein-protein interaction databases

    IntActiP74163. 1 interaction.
    STRINGi1148.slr1476.

    Structurei

    3D structure databases

    ProteinModelPortaliP74163.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATCase/OTCase family.Curated

    Phylogenomic databases

    eggNOGiCOG0540.
    HOGENOMiHOG000022685.
    KOiK00609.
    OMAiMTVFYEN.
    OrthoDBiEOG61KBJZ.
    PhylomeDBiP74163.

    Family and domain databases

    Gene3Di3.40.50.1370. 2 hits.
    HAMAPiMF_00001. Asp_carb_tr.
    InterProiIPR006132. Asp/Orn_carbamoyltranf_P-bd.
    IPR006130. Asp/Orn_carbamoylTrfase.
    IPR002082. Asp_carbamoyltransf.
    IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
    [Graphical view]
    PfamiPF00185. OTCace. 1 hit.
    PF02729. OTCace_N. 1 hit.
    [Graphical view]
    PRINTSiPR00100. AOTCASE.
    PR00101. ATCASE.
    SUPFAMiSSF53671. SSF53671. 1 hit.
    TIGRFAMsiTIGR00670. asp_carb_tr. 1 hit.
    PROSITEiPS00097. CARBAMOYLTRANSFERASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P74163-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTMVASWTRN HILDLTDWRG EELDIVLQTA TTFQQVLSGQ TKKVPALQGQ    50
    VVTNLFFEPS TRTRSSFELA AKRLSADVMN FSPGTSSLTK GETILDTAKT 100
    YLAMGSDIFV IRHQQAGVPH FIASQMDRLQ TGVKVLNAGD GQHEHPSQGL 150
    LDLFTICSQF APDNPAIQCL QGKKIAVVGD ILHSRVARSN LWSLTTAGAD 200
    VHLAGPPTLL PKEFQQLTLA PGSGKLHCHW QLQPALEGAD IVMTLRLQKE 250
    RMTAHLLPSL REYHHYFGIT HDRLKVCQPG VKVLHPGPVN RGVEISSELM 300
    DDPDISLIQD QVTSGVAIRM ALLYLLGTVQ E 331
    Length:331
    Mass (Da):36,394
    Last modified:February 1, 1997 - v1
    Checksum:iD3272435A464861A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000022 Genomic DNA. Translation: BAA18252.1.
    PIRiS75691.
    RefSeqiNP_441572.1. NC_000911.1.
    YP_005651630.1. NC_017277.1.
    YP_007451454.1. NC_020286.1.

    Genome annotation databases

    EnsemblBacteriaiBAA18252; BAA18252; BAA18252.
    GeneIDi953090.
    KEGGisyn:slr1476.
    syy:SYNGTS_1677.
    syz:MYO_116940.
    PATRICi23840575. VBISynSp132158_1843.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000022 Genomic DNA. Translation: BAA18252.1 .
    PIRi S75691.
    RefSeqi NP_441572.1. NC_000911.1.
    YP_005651630.1. NC_017277.1.
    YP_007451454.1. NC_020286.1.

    3D structure databases

    ProteinModelPortali P74163.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P74163. 1 interaction.
    STRINGi 1148.slr1476.

    Proteomic databases

    PaxDbi P74163.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAA18252 ; BAA18252 ; BAA18252 .
    GeneIDi 953090.
    KEGGi syn:slr1476.
    syy:SYNGTS_1677.
    syz:MYO_116940.
    PATRICi 23840575. VBISynSp132158_1843.

    Phylogenomic databases

    eggNOGi COG0540.
    HOGENOMi HOG000022685.
    KOi K00609.
    OMAi MTVFYEN.
    OrthoDBi EOG61KBJZ.
    PhylomeDBi P74163.

    Enzyme and pathway databases

    UniPathwayi UPA00070 ; UER00116 .

    Family and domain databases

    Gene3Di 3.40.50.1370. 2 hits.
    HAMAPi MF_00001. Asp_carb_tr.
    InterProi IPR006132. Asp/Orn_carbamoyltranf_P-bd.
    IPR006130. Asp/Orn_carbamoylTrfase.
    IPR002082. Asp_carbamoyltransf.
    IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
    [Graphical view ]
    Pfami PF00185. OTCace. 1 hit.
    PF02729. OTCace_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00100. AOTCASE.
    PR00101. ATCASE.
    SUPFAMi SSF53671. SSF53671. 1 hit.
    TIGRFAMsi TIGR00670. asp_carb_tr. 1 hit.
    PROSITEi PS00097. CARBAMOYLTRANSFERASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
      Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
      , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
      DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PCC 6803 / Kazusa.

    Entry informationi

    Entry nameiPYRB_SYNY3
    AccessioniPrimary (citable) accession number: P74163
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 102 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families
    3. Synechocystis PCC 6803
      Synechocystis (strain PCC 6803): entries and gene names

    External Data

    Dasty 3