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P74163 (PYRB_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 101. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Aspartate carbamoyltransferase

EC=2.1.3.2
Alternative name(s):
Aspartate transcarbamylase
Short name=ATCase
Gene names
Name:pyrB
Ordered Locus Names:slr1476
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length331 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate. HAMAP-Rule MF_00001

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3. HAMAP-Rule MF_00001

Sequence similarities

Belongs to the ATCase/OTCase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 331331Aspartate carbamoyltransferase HAMAP-Rule MF_00001
PRO_0000113218

Sequences

Sequence LengthMass (Da)Tools
P74163 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: D3272435A464861A

FASTA33136,394
        10         20         30         40         50         60 
MTMVASWTRN HILDLTDWRG EELDIVLQTA TTFQQVLSGQ TKKVPALQGQ VVTNLFFEPS 

        70         80         90        100        110        120 
TRTRSSFELA AKRLSADVMN FSPGTSSLTK GETILDTAKT YLAMGSDIFV IRHQQAGVPH 

       130        140        150        160        170        180 
FIASQMDRLQ TGVKVLNAGD GQHEHPSQGL LDLFTICSQF APDNPAIQCL QGKKIAVVGD 

       190        200        210        220        230        240 
ILHSRVARSN LWSLTTAGAD VHLAGPPTLL PKEFQQLTLA PGSGKLHCHW QLQPALEGAD 

       250        260        270        280        290        300 
IVMTLRLQKE RMTAHLLPSL REYHHYFGIT HDRLKVCQPG VKVLHPGPVN RGVEISSELM 

       310        320        330 
DDPDISLIQD QVTSGVAIRM ALLYLLGTVQ E 

« Hide

References

[1]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000022 Genomic DNA. Translation: BAA18252.1.
PIRS75691.
RefSeqNP_441572.1. NC_000911.1.
YP_005651630.1. NC_017277.1.
YP_007451454.1. NC_020286.1.

3D structure databases

ProteinModelPortalP74163.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP74163. 1 interaction.
STRING1148.slr1476.

Proteomic databases

PaxDbP74163.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA18252; BAA18252; BAA18252.
GeneID953090.
KEGGsyn:slr1476.
syy:SYNGTS_1677.
syz:MYO_116940.
PATRIC23840575. VBISynSp132158_1843.

Phylogenomic databases

eggNOGCOG0540.
HOGENOMHOG000022685.
KOK00609.
OMAMTVFYEN.
OrthoDBEOG61KBJZ.
PhylomeDBP74163.

Enzyme and pathway databases

UniPathwayUPA00070; UER00116.

Family and domain databases

Gene3D3.40.50.1370. 2 hits.
HAMAPMF_00001. Asp_carb_tr.
InterProIPR006132. Asp/Orn_carbamoyltranf_P-bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR002082. Asp_carbamoyltransf.
IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
[Graphical view]
PfamPF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
[Graphical view]
PRINTSPR00100. AOTCASE.
PR00101. ATCASE.
SUPFAMSSF53671. SSF53671. 1 hit.
TIGRFAMsTIGR00670. asp_carb_tr. 1 hit.
PROSITEPS00097. CARBAMOYLTRANSFERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePYRB_SYNY3
AccessionPrimary (citable) accession number: P74163
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: July 9, 2014
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways