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P74120

- DER_SYNY3

UniProt

P74120 - DER_SYNY3

Protein

GTPase Der

Gene

der

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 104 (01 Oct 2014)
      Sequence version 1 (01 Feb 1997)
      Previous versions | rss
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    Functioni

    GTPase that plays an essential role in the late steps of ribosome biogenesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi10 – 178GTP 1UniRule annotation
    Nucleotide bindingi57 – 615GTP 1UniRule annotation
    Nucleotide bindingi120 – 1234GTP 1UniRule annotation
    Nucleotide bindingi183 – 1908GTP 2UniRule annotation
    Nucleotide bindingi230 – 2345GTP 2UniRule annotation
    Nucleotide bindingi295 – 2984GTP 2UniRule annotation

    GO - Molecular functioni

    1. GTP binding Source: UniProtKB-HAMAP
    2. nucleoside-triphosphatase activity Source: InterPro

    GO - Biological processi

    1. ribosome biogenesis Source: UniProtKB-KW

    Keywords - Biological processi

    Ribosome biogenesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GTPase DerUniRule annotation
    Alternative name(s):
    GTP-binding protein EngAUniRule annotation
    Gene namesi
    Name:derUniRule annotation
    Synonyms:engA
    Ordered Locus Names:slr1974
    OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
    Taxonomic identifieri1111708 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 452452GTPase DerPRO_0000179063Add
    BLAST

    Proteomic databases

    PaxDbiP74120.

    Interactioni

    Subunit structurei

    Associates with the 50S ribosomal subunit.UniRule annotation

    Protein-protein interaction databases

    IntActiP74120. 11 interactions.
    STRINGi1148.slr1974.

    Structurei

    3D structure databases

    ProteinModelPortaliP74120.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini4 – 169166EngA-type G 1Add
    BLAST
    Domaini177 – 352176EngA-type G 2Add
    BLAST
    Domaini353 – 43987KH-likeUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.UniRule annotation
    Contains 1 KH-like domain.UniRule annotation

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiCOG1160.
    HOGENOMiHOG000242861.
    KOiK03977.
    OMAiISVDWDW.
    OrthoDBiEOG6DC6K1.
    PhylomeDBiP74120.

    Family and domain databases

    Gene3Di3.30.300.20. 1 hit.
    3.40.50.300. 2 hits.
    HAMAPiMF_00195. GTPase_Der.
    InterProiIPR003593. AAA+_ATPase.
    IPR016484. GTP-bd_EngA.
    IPR006073. GTP_binding_domain.
    IPR015946. KH_dom-like_a/b.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    [Graphical view]
    PANTHERiPTHR11649:SF5. PTHR11649:SF5. 1 hit.
    PfamiPF01926. MMR_HSR1. 2 hits.
    [Graphical view]
    PIRSFiPIRSF006485. GTP-binding_EngA. 1 hit.
    PRINTSiPR00326. GTP1OBG.
    SMARTiSM00382. AAA. 2 hits.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 2 hits.
    TIGRFAMsiTIGR03594. GTPase_EngA. 1 hit.
    TIGR00231. small_GTP. 2 hits.
    PROSITEiPS51712. G_ENGA. 2 hits.
    [Graphical view]
    ProtoNetiSearch...

    Sequencei

    Sequence statusi: Complete.

    P74120-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSLPIVAIIG RPNVGKSTFV NRLAGNQQAI VHDQPGITRD RTYRPAFWRD    50
    RDFQVVDTGG LVFNDDSEFL PEIREQANLA LAEAKAAIFV VDGQQGPTAS 100
    DEEIAQWLRQ QSVPVILAVN KCESPDQGAI QAAEFWHLGL GEPYPMSAIH 150
    GSGTGDLLDA LLEYLPAPQE EPEEDEIKVA IVGRPNVGKS SLLNALTGEQ 200
    RAIVSPISGT TRDAIDMVVE RNGQKYRLID TAGIRRKKNV DYGAEFFGIN 250
    RAFKAIRRAD VVLFVLDVLD GVTEQDLKLA GRIIEDGRAV VLVINKWDAV 300
    EKDSYTIYEH REQLMARLYF MDWAEMIFVS AQTGLRVQKI LDCVDIAAQE 350
    HRRRVTTAVI NEVLEEAVSW HSPPTTRQGK QGKIYYGTQV STQPPAIALF 400
    VNDPNRFNDN YRRYIEKQFR KQLGFFGSPI RLFWRGKKVR EMEGSRNRAT 450
    KV 452
    Length:452
    Mass (Da):50,826
    Last modified:February 1, 1997 - v1
    Checksum:i7FF771EAF7D6CC76
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000022 Genomic DNA. Translation: BAA18206.1.
    PIRiS75645.
    RefSeqiNP_441526.1. NC_000911.1.
    YP_005651584.1. NC_017277.1.
    YP_007451408.1. NC_020286.1.

    Genome annotation databases

    EnsemblBacteriaiBAA18206; BAA18206; BAA18206.
    GeneIDi954938.
    KEGGisyn:slr1974.
    syy:SYNGTS_1631.
    syz:MYO_116460.
    PATRICi23840475. VBISynSp132158_1795.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000022 Genomic DNA. Translation: BAA18206.1 .
    PIRi S75645.
    RefSeqi NP_441526.1. NC_000911.1.
    YP_005651584.1. NC_017277.1.
    YP_007451408.1. NC_020286.1.

    3D structure databases

    ProteinModelPortali P74120.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P74120. 11 interactions.
    STRINGi 1148.slr1974.

    Proteomic databases

    PaxDbi P74120.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAA18206 ; BAA18206 ; BAA18206 .
    GeneIDi 954938.
    KEGGi syn:slr1974.
    syy:SYNGTS_1631.
    syz:MYO_116460.
    PATRICi 23840475. VBISynSp132158_1795.

    Phylogenomic databases

    eggNOGi COG1160.
    HOGENOMi HOG000242861.
    KOi K03977.
    OMAi ISVDWDW.
    OrthoDBi EOG6DC6K1.
    PhylomeDBi P74120.

    Family and domain databases

    Gene3Di 3.30.300.20. 1 hit.
    3.40.50.300. 2 hits.
    HAMAPi MF_00195. GTPase_Der.
    InterProi IPR003593. AAA+_ATPase.
    IPR016484. GTP-bd_EngA.
    IPR006073. GTP_binding_domain.
    IPR015946. KH_dom-like_a/b.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    [Graphical view ]
    PANTHERi PTHR11649:SF5. PTHR11649:SF5. 1 hit.
    Pfami PF01926. MMR_HSR1. 2 hits.
    [Graphical view ]
    PIRSFi PIRSF006485. GTP-binding_EngA. 1 hit.
    PRINTSi PR00326. GTP1OBG.
    SMARTi SM00382. AAA. 2 hits.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 2 hits.
    TIGRFAMsi TIGR03594. GTPase_EngA. 1 hit.
    TIGR00231. small_GTP. 2 hits.
    PROSITEi PS51712. G_ENGA. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
      Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
      , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
      DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PCC 6803 / Kazusa.

    Entry informationi

    Entry nameiDER_SYNY3
    AccessioniPrimary (citable) accession number: P74120
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 104 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Synechocystis PCC 6803
      Synechocystis (strain PCC 6803): entries and gene names

    External Data

    Dasty 3

    Similar proteinsi