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P74120

- DER_SYNY3

UniProt

P74120 - DER_SYNY3

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Protein
GTPase Der
Gene
der, engA, slr1974
Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

GTPase that plays an essential role in the late steps of ribosome biogenesis By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi10 – 178GTP 1 Reviewed prediction
Nucleotide bindingi57 – 615GTP 1 Reviewed prediction
Nucleotide bindingi120 – 1234GTP 1 Reviewed prediction
Nucleotide bindingi183 – 1908GTP 2 Reviewed prediction
Nucleotide bindingi230 – 2345GTP 2 Reviewed prediction
Nucleotide bindingi295 – 2984GTP 2 Reviewed prediction

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-HAMAP
  2. nucleoside-triphosphatase activity Source: InterPro

GO - Biological processi

  1. ribosome biogenesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Ribosome biogenesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
GTPase Der
Alternative name(s):
GTP-binding protein EngA
Gene namesi
Name:der
Synonyms:engA
Ordered Locus Names:slr1974
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 452452GTPase DerUniRule annotation
PRO_0000179063Add
BLAST

Proteomic databases

PaxDbiP74120.

Interactioni

Subunit structurei

Associates with the 50S ribosomal subunit By similarity.

Protein-protein interaction databases

IntActiP74120. 11 interactions.
STRINGi1148.slr1974.

Structurei

3D structure databases

ProteinModelPortaliP74120.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 169166EngA-type G 1
Add
BLAST
Domaini177 – 352176EngA-type G 2
Add
BLAST
Domaini353 – 43987KH-like
Add
BLAST

Sequence similaritiesi

Contains 1 KH-like domain.

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG1160.
HOGENOMiHOG000242861.
KOiK03977.
OMAiISVDWDW.
OrthoDBiEOG6DC6K1.
PhylomeDBiP74120.

Family and domain databases

Gene3Di3.30.300.20. 1 hit.
3.40.50.300. 2 hits.
HAMAPiMF_00195. GTPase_Der.
InterProiIPR003593. AAA+_ATPase.
IPR016484. GTP-bd_EngA.
IPR006073. GTP_binding_domain.
IPR015946. KH_dom-like_a/b.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
[Graphical view]
PANTHERiPTHR11649:SF5. PTHR11649:SF5. 1 hit.
PfamiPF01926. MMR_HSR1. 2 hits.
[Graphical view]
PIRSFiPIRSF006485. GTP-binding_EngA. 1 hit.
PRINTSiPR00326. GTP1OBG.
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR03594. GTPase_EngA. 1 hit.
TIGR00231. small_GTP. 2 hits.
PROSITEiPS51712. G_ENGA. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P74120-1 [UniParc]FASTAAdd to Basket

« Hide

MSLPIVAIIG RPNVGKSTFV NRLAGNQQAI VHDQPGITRD RTYRPAFWRD    50
RDFQVVDTGG LVFNDDSEFL PEIREQANLA LAEAKAAIFV VDGQQGPTAS 100
DEEIAQWLRQ QSVPVILAVN KCESPDQGAI QAAEFWHLGL GEPYPMSAIH 150
GSGTGDLLDA LLEYLPAPQE EPEEDEIKVA IVGRPNVGKS SLLNALTGEQ 200
RAIVSPISGT TRDAIDMVVE RNGQKYRLID TAGIRRKKNV DYGAEFFGIN 250
RAFKAIRRAD VVLFVLDVLD GVTEQDLKLA GRIIEDGRAV VLVINKWDAV 300
EKDSYTIYEH REQLMARLYF MDWAEMIFVS AQTGLRVQKI LDCVDIAAQE 350
HRRRVTTAVI NEVLEEAVSW HSPPTTRQGK QGKIYYGTQV STQPPAIALF 400
VNDPNRFNDN YRRYIEKQFR KQLGFFGSPI RLFWRGKKVR EMEGSRNRAT 450
KV 452
Length:452
Mass (Da):50,826
Last modified:February 1, 1997 - v1
Checksum:i7FF771EAF7D6CC76
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000022 Genomic DNA. Translation: BAA18206.1.
PIRiS75645.
RefSeqiNP_441526.1. NC_000911.1.
YP_005651584.1. NC_017277.1.
YP_007451408.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA18206; BAA18206; BAA18206.
GeneIDi954938.
KEGGisyn:slr1974.
syy:SYNGTS_1631.
syz:MYO_116460.
PATRICi23840475. VBISynSp132158_1795.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000022 Genomic DNA. Translation: BAA18206.1 .
PIRi S75645.
RefSeqi NP_441526.1. NC_000911.1.
YP_005651584.1. NC_017277.1.
YP_007451408.1. NC_020286.1.

3D structure databases

ProteinModelPortali P74120.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P74120. 11 interactions.
STRINGi 1148.slr1974.

Proteomic databases

PaxDbi P74120.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA18206 ; BAA18206 ; BAA18206 .
GeneIDi 954938.
KEGGi syn:slr1974.
syy:SYNGTS_1631.
syz:MYO_116460.
PATRICi 23840475. VBISynSp132158_1795.

Phylogenomic databases

eggNOGi COG1160.
HOGENOMi HOG000242861.
KOi K03977.
OMAi ISVDWDW.
OrthoDBi EOG6DC6K1.
PhylomeDBi P74120.

Family and domain databases

Gene3Di 3.30.300.20. 1 hit.
3.40.50.300. 2 hits.
HAMAPi MF_00195. GTPase_Der.
InterProi IPR003593. AAA+_ATPase.
IPR016484. GTP-bd_EngA.
IPR006073. GTP_binding_domain.
IPR015946. KH_dom-like_a/b.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
[Graphical view ]
PANTHERi PTHR11649:SF5. PTHR11649:SF5. 1 hit.
Pfami PF01926. MMR_HSR1. 2 hits.
[Graphical view ]
PIRSFi PIRSF006485. GTP-binding_EngA. 1 hit.
PRINTSi PR00326. GTP1OBG.
SMARTi SM00382. AAA. 2 hits.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 2 hits.
TIGRFAMsi TIGR03594. GTPase_EngA. 1 hit.
TIGR00231. small_GTP. 2 hits.
PROSITEi PS51712. G_ENGA. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiDER_SYNY3
AccessioniPrimary (citable) accession number: P74120
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: February 1, 1997
Last modified: July 9, 2014
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3

Similar proteinsi