P74089 (CYSE_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Serine acetyltransferase
Short name=SAT
EC=2.3.1.30

Gene names

Name:	cysE
Ordered Locus Names:	slr1348

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa)

Taxonomic identifier

1111708 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechocystis

Protein attributes

Sequence length	249 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acetyl-CoA + L-serine = CoA + O-acetyl-L-serine.
Pathway	Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 1/2.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the transferase hexapeptide repeat family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Cysteine biosynthesis
Cellular component	Cytoplasm
Domain	Repeat
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cysteine biosynthetic process from serine Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	serine O-acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 249	249	Serine acetyltransferase		PRO_0000068687
Experimental info
	Sequence conflict	80	1	I → S in BAA02919. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P74089 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: ED5EC58D659DCFBB	FASTA	249	27,336
	10 20 30 40 50 60 MLNSLIADFR IIFERDPAAR NWLEVLFCYP GLQALLIHRF SHRLYTLGLP FFPRLMSHLA 70 80 90 100 110 120 RFFTGIEIHP GAQIGQGVFI DHGMGVVIGE TAIVGDYSLI YQGVTLGGTG KESGKRHPTL 130 140 150 160 170 180 GENVVVGAGA KVLGNIAIGD NVRIGAGSVV LRDVPADFTV VGVPGRMVHP SGERVNPLEH 190 200 210 220 230 240 GKLPDSEGKV IRLLLERIEL LEQQVATLQQ QQSEQAWESD YRSCSETDRE PVLCRLGDRE IEEFLGGTL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence analysis of a DNA fragment from Synechocystis PCC6803 containing genes homologous to cysE (serine acetyltransferase) and pgi (glucose-6-phosphate isomerase)." Sakamoto T., Wada H., Nishida I., Ohta H., Murata N. Plant Mol. Biol. 29:187-187(1995) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27184 / PCC 6803 / N-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D13777 Genomic DNA. Translation: BAA02919.1. BA000022 Genomic DNA. Translation: BAA18167.1.
PIR	S75606.
RefSeq	NP_441487.1. NC_000911.1.
3D structure databases
ProteinModelPortal	P74089.
ModBase	Search...
Protein-protein interaction databases
IntAct	P74089. 2 interactions.
STRING	P74089.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	954867.
GenomeReviews	Gene locus slr1348 in contig BA000022_GR.
KEGG	syn:slr1348.
NMPDR	fig|1148.1.peg.1588.
PATRIC	23840387. VBISynSp132158_1751.
Phylogenomic databases
eggNOG	COG1045.
HOGENOM	HBG754554.
OMA	SLIADFR.
PhylomeDB	P74089.
Enzyme and pathway databases
BioCyc	SSP1148:SLR1348-MONOMER.
Family and domain databases
InterPro	IPR001451. Hexapep_transf. IPR018357. Hexapep_transf_CS. IPR005881. Ser_O-AcTrfase. IPR011004. Trimer_LpxA-like. [Graphical view]
KO	K00640.
Pfam	PF00132. Hexapep. 2 hits. [Graphical view]
PIRSF	PIRSF000441. CysE. 1 hit.
SUPFAM	SSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMs	TIGR01172. CysE. 1 hit.
PROSITE	PS00101. HEXAPEP_TRANSFERASES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CYSE_SYNY3

Accession

Primary (citable) accession number: P74089
Secondary accession number(s): Q55209

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	January 25, 2012
This is version 73 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program