P73930 (FTSY_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Signal recognition particle receptor FtsY
Short name=SRP receptor

Gene names

Name:	ftsY
Ordered Locus Names:	slr2102

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]

Taxonomic identifier

1111708 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Synechocystis › Synechocystis sp. PCC 6803

Protein attributes

Sequence length	504 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) By similarity. HAMAP-Rule MF_00920
Subunit structure	Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY By similarity.
Subcellular location	Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm By similarity HAMAP-Rule MF_00920.
Sequence similarities	Belongs to the GTP-binding SRP family. FtsY subfamily.

Ontologies

Keywords
Cellular component	Cell inner membrane Cell membrane Cytoplasm Membrane
Ligand	GTP-binding Nucleotide-binding
Molecular function	Receptor
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	SRP-dependent cotranslational protein targeting to membrane Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell intrinsic to plasma membrane Inferred from electronic annotation. Source: HAMAP
Molecular_function	GTP binding Inferred from electronic annotation. Source: HAMAP GTPase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 504	504	Signal recognition particle receptor FtsY HAMAP-Rule MF_00920		PRO_0000101146
Regions
	Nucleotide binding	308 – 315	8	GTP By similarity
	Nucleotide binding	391 – 395	5	GTP By similarity
	Nucleotide binding	455 – 458	4	GTP By similarity

Sequences

	Sequence		Length	Mass (Da)
	P73930 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 5201176F5C5AE09A	FASTA	504	53,870
	10 20 30 40 50 60 MFNWFRRQFG KDNTAPESAP PEGAEVSPEL APEVIQAETE SPSEEDSQTT ELAAPPPEEP 70 80 90 100 110 120 SSDTANPDDY LQWAKAAYQN IQARKAETVS PPESAAAITV EAGIEETAEE IVVAPESDQA 130 140 150 160 170 180 TATEADLPSP ETEITTGPAW LQKSDRLEAL KETAVEEATV AGTLTAESMA MDDDFMWSAK 190 200 210 220 230 240 VLAAQGRSAA DVSAEEIDWL RKLRQGLSKT RVNLVNQLKS IVGQGPLNEA AVEEIEAILL 250 260 270 280 290 300 QADVGVEATD YIITTLQDKL REEALPPEQA IEFLKEILRS ILDRPLLSLP SAEFAPEAEG 310 320 330 340 350 360 LNVWLLTGVN GAGKTTTIGK LAFMAKQSGY DCVIAAADTF RAAAVEQVKV WGERSGVPVI 370 380 390 400 410 420 ANPGQNTDPA AVVYDGISAA QSRNVNLLLV DTAGRLQNKK NLMDELAKIR RIIDKKAPNA 430 440 450 460 470 480 TVESLLVLDA TLGQNGLRQA EVFAEAAKLS GVVLTKLDGS AKGGVALAVA QQLNLPIRFI 490 500 GAGEGIEDLR PFSSYEFVEA LLNG

References

[1]

"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000022 Genomic DNA. Translation: BAA17996.1.
PIR	S75134.
RefSeq	NP_441316.1. NC_000911.1. YP_005651373.1. NC_017277.1. YP_007451198.1. NC_020286.1.
3D structure databases
ProteinModelPortal	P73930.
ModBase	Search...
Protein-protein interaction databases
IntAct	P73930. 4 interactions.
STRING	1148.slr2102.
Proteomic databases
PaxDb	P73930.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAA17996; BAA17996; BAA17996.
GeneID	12255792. 14616855. 954661.
KEGG	syn:slr2102. syy:SYNGTS_1420.
PATRIC	23840000. VBISynSp132158_1560.
Phylogenomic databases
eggNOG	COG0552.
HOGENOM	HOG000036278.
KO	K03110.
OMA	KNIQQRQ.
Family and domain databases
HAMAP	MF_00920. FtsY.
InterPro	IPR003593. AAA+_ATPase. IPR013822. Signal_recog_particl_SRP54_hlx. IPR004390. SR_rcpt_FtsY. IPR000897. SRP54_GTPase_dom. [Graphical view]
Pfam	PF00448. SRP54. 1 hit. PF02881. SRP54_N. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. SM00962. SRP54. 1 hit. SM00963. SRP54_N. 1 hit. [Graphical view]
SUPFAM	SSF47364. SRP54. 1 hit.
TIGRFAMs	TIGR00064. ftsY. 1 hit.
PROSITE	PS00300. SRP54. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FTSY_SYNY3

Accession

Primary (citable) accession number: P73930

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	February 1, 1997
Last modified:	May 1, 2013
This is version 92 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program