Prephenate dehydrogenase - Synechocystis sp. (strain PCC 6803 / Kazusa)

Preferred order of sections

Names and origin

Protein names

Submitted name:
Prephenate dehydrogenase EMBL BAA17970.1

Gene names

Name:	tyrA EMBL BAA17970.1
Ordered Locus Names:	slr2081

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa)

Taxonomic identifier

1111708 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechocystis

Protein attributes

Sequence length	279 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	NADP PDB 2F1K Nucleotide-binding PDB 2F1K
Technical term	3D-structure PDB 2F1K Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	tyrosine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	cyclohexadienyl dehydrogenase activity Inferred from electronic annotation. Source: EC nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro prephenate dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: InterPro prephenate dehydrogenase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Regions

Nucleotide binding

10 – 11

2

NADP PDB 2F1K

Nucleotide binding

30 – 35

6

NADP PDB 2F1K

Nucleotide binding

65 – 66

2

NADP PDB 2F1K

Nucleotide binding

117 – 121

5

NADP PDB 2F1K

Sites

Binding site

92

1

NADP PDB 2F1K

Sequences

Sequence

Length

Mass (Da)

Tools

P73906 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 492144A2C2DBCC88
Show »

FASTA

279

30,216

        10         20         30         40         50         60 
MKIGVVGLGL IGASLAGDLR RRGHYLIGVS RQQSTCEKAV ERQLVDEAGQ DLSLLQTAKI 

        70         80         90        100        110        120 
IFLCTPIQLI LPTLEKLIPH LSPTAIVTDV ASVKTAIAEP ASQLWSGFIG GHPMAGTAAQ 

       130        140        150        160        170        180 
GIDGAEENLF VNAPYVLTPT EYTDPEQLAC LRSVLEPLGV KIYLCTPADH DQAVAWISHL 

       190        200        210        220        230        240 
PVMVSAALIQ ACAGEKDGDI LKLAQNLASS GFRDTSRVGG GNPELGTMMA TYNQRALLKS 

       250        260        270 
LQDYRQHLDQ LITLISNQQW PELHRLLQQT NGDRDKYVE

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. Tabata S. DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27184 / PCC 6803 / N-1.
[2]	"Biochemical characterization and crystal structure of Synechocystis arogenate dehydrogenase provide insights into catalytic reaction." Legrand P., Dumas R., Seux M., Rippert P., Ravelli R., Ferrer J.L., Matringe M. Structure 14:767-776(2006) [PubMed: 16615917] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.55 ANGSTROMS) IN COMPLEX WITH NADP.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

BA000022 Genomic DNA. Translation: BAA17970.1.

PIR

S75108.

RefSeq

NP_441290.1. NC_000911.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2F1K	X-ray	1.55	A/B/C/D	1-279	[»]

ProteinModelPortal

P73906.

SMR

P73906. Positions 1-279.

ModBase

Search...

Protein-protein interaction databases

DIP

DIP-29098N.

STRING

P73906.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

954635.

GenomeReviews

Gene locus slr2081 in contig BA000022_GR.

KEGG

syn:slr2081.

NMPDR

fig|1148.1.peg.1391.

PATRIC

23839936. VBISynSp132158_1529.

Phylogenomic databases

eggNOG

COG0287.

HOGENOM

HBG544990.

OMA

FENAFYI.

PhylomeDB

P73906.

ProtClustDB

PRK07417.

Enzyme and pathway databases

BioCyc

SSP1148:SLR2081-MONOMER.

BRENDA

1.3.1.78. 275926.

Family and domain databases

InterPro

IPR008927. 6-PGluconate_DH_C-like.
IPR016040. NAD(P)-bd_dom.
IPR003099. Prephen_DH.
[Graphical view]

Gene3D

G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.

KO

K15226.

Pfam

PF02153. PDH. 1 hit.
[Graphical view]

SUPFAM

SSF48179. 6DGDH_C_like. 1 hit.

PROSITE

PS51176. PDH_ADH. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

P73906_SYNY3

Accession

Primary (citable) accession number: P73906

Entry history

Integrated into UniProtKB/TrEMBL:	February 1, 1997
Last sequence update:	February 1, 1997
Last modified:	January 25, 2012
This is version 87 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)