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Protein

Potassium-transporting ATPase ATP-binding subunit

Gene

kdpB

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system.UniRule annotation

Catalytic activityi

ATP + H2O + K+(Out) = ADP + phosphate + K+(In).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei3214-aspartylphosphate intermediateUniRule annotation1
Binding sitei358ATPUniRule annotation1
Binding sitei362ATPUniRule annotation1
Binding sitei408ATPUniRule annotation1
Metal bindingi531MagnesiumUniRule annotation1
Metal bindingi535MagnesiumUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi389 – 396ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase
Biological processIon transport, Potassium transport, Transport
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding, Potassium

Names & Taxonomyi

Protein namesi
Recommended name:
Potassium-transporting ATPase ATP-binding subunitUniRule annotation (EC:3.6.3.12UniRule annotation)
Alternative name(s):
ATP phosphohydrolase [potassium-transporting] B chainUniRule annotation
Potassium-binding and translocating subunit BUniRule annotation
Potassium-translocating ATPase B chainUniRule annotation
Gene namesi
Name:kdpBUniRule annotation
Ordered Locus Names:slr1729
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesMerismopediaceaeSynechocystis
Proteomesi
  • UP000001425 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei44 – 64HelicalUniRule annotationAdd BLAST21
Transmembranei78 – 98HelicalUniRule annotationAdd BLAST21
Transmembranei233 – 253HelicalUniRule annotationAdd BLAST21
Transmembranei268 – 288HelicalUniRule annotationAdd BLAST21
Transmembranei601 – 621HelicalUniRule annotationAdd BLAST21
Transmembranei627 – 647HelicalUniRule annotationAdd BLAST21
Transmembranei665 – 685HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000461461 – 690Potassium-transporting ATPase ATP-binding subunitAdd BLAST690

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiP73867.

Interactioni

Subunit structurei

The system is composed of three essential subunits: KdpA, KdpB and KdpC.UniRule annotation

Protein-protein interaction databases

IntActiP73867. 6 interactors.
STRINGi1148.SYNGTS_1353.

Structurei

3D structure databases

ProteinModelPortaliP73867.
SMRiP73867.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000244113.
InParanoidiP73867.
KOiK01547.
OMAiILWLWFT.
PhylomeDBiP73867.

Family and domain databases

CDDicd02078. P-type_ATPase_K. 1 hit.
Gene3Di3.40.1110.10. 1 hit.
3.40.50.1000. 1 hit.
HAMAPiMF_00285. KdpB. 1 hit.
InterProiView protein in InterPro
IPR023299. ATPase_P-typ_cyto_dom_N.
IPR018303. ATPase_P-typ_P_site.
IPR023298. ATPase_P-typ_TM_dom_sf.
IPR008250. ATPase_P-typ_transduc_dom_A_sf.
IPR036412. HAD-like_sf.
IPR023214. HAD_sf.
IPR006391. P-type_ATPase_bsu_IA.
IPR001757. P_typ_ATPase.
PANTHERiPTHR43743. PTHR43743. 1 hit.
SUPFAMiSSF56784. SSF56784. 3 hits.
SSF81653. SSF81653. 1 hit.
SSF81665. SSF81665. 3 hits.
TIGRFAMsiTIGR01494. ATPase_P-type. 2 hits.
TIGR01497. kdpB. 1 hit.
PROSITEiView protein in PROSITE
PS00154. ATPASE_E1_E2. 1 hit.

Sequencei

Sequence statusi: Complete.

P73867-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSTSTVRQP GGPRQQRRHT PKANLSDLYQ RAFKEAWVKL NPKIMVKNPV
60 70 80 90 100
MFMVWVGTLI TGMLTLNPNL FGVTGTSAMF NGLVTVILLF TVLFANFAEA
110 120 130 140 150
VAEGRGKAQA DALRSTQTQT YAQRILADGS LEMVSSTHLR KGDRIVVSVG
160 170 180 190 200
DIIPADGEVL EGVASVDESA ITGESAPVLK EPGSDVASSV TGGTRIISDE
210 220 230 240 250
LIIRVTADPG KGFIDRMIDL VEGAERSKTP NEIALTVLLA VLTLVFLIVV
260 270 280 290 300
ATLPPPANYI DSPVSITLLI ALLVALIPTT IGGLLSAIGI AGMDRVAQFN
310 320 330 340 350
VVATSGRAVE ACGDINTLVL DKTGTITLGN RLAETFLPVN GHSLKEVAAI
360 370 380 390 400
ALAASIFDTT PEGKSIVRLA EKMGATLDFD RQQAEGVEFS ARTRMSGTDL
410 420 430 440 450
PDGSEVRKGA VDAIRGFVRS RGGKSPTGLD EAYGKVSHLG GTPLAVCRND
460 470 480 490 500
EIYGVIYLKD IIKPGIQERF NQLRRMGVRT VMLTGDNRIT ASVIAKEAGV
510 520 530 540 550
DDFIAEATPE DKIQVIQQEQ AAGKLVAMTG DGTNDAPALA QANVGLAMNS
560 570 580 590 600
GTQAAKEAAN MVDLDSDPTK LIDLVTIGKQ LLITRGALTT FSLANDIAKY
610 620 630 640 650
FAIIPAMFAG IGIGALNIMD LKSPQSAVLS ALIYNALIIP ALIPLALRGV
660 670 680 690
KFRPLSADQL LQRNILVYGL GGIIVPFVAI KLIDLGISLL
Length:690
Mass (Da):72,971
Last modified:February 1, 1997 - v1
Checksum:i0643C8C9C11B9D5E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA17929.1.
PIRiS75067.

Genome annotation databases

EnsemblBacteriaiBAA17929; BAA17929; BAA17929.
KEGGisyn:slr1729.

Similar proteinsi

Entry informationi

Entry nameiKDPB_SYNY3
AccessioniPrimary (citable) accession number: P73867
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: November 22, 2017
This is version 143 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names