P73849 (COMB_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable 2-phosphosulfolactate phosphatase
EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	slr1718

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa)

Taxonomic identifier

1111708 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechocystis

Protein attributes

Sequence length	241 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity. HAMAP MF_00490
Sequence similarities	Belongs to the ComB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 241	241	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_0000081476

Sequences

	Sequence		Length	Mass (Da)
	P73849 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 46D75910F3D53042	FASTA	241	26,046
	10 20 30 40 50 60 MEIFVYHTPE LTPDQSLPDC AVVIDVLRAT TTIATALKVG AEAVQVFSSL DDLMATSESW 70 80 90 100 110 120 PGEKRLRAGE RGGAAVAGYD LGNSPLDCTS ELMAGKRLFL STTNGTRALQ RVKDCPQLVT 130 140 150 160 170 180 ASLVNRGAAV DYLAQTQPKT VWLLGSGWEG GYSLEDTVCA GAIASLLREK GIDFTVGNDE 190 200 210 220 230 240 VVAAQSLYRQ WRSDLLNLFK QASHGQRLLK LDRLEDLRYC ATEDLIDILP KQVSPGVLTA A

References

[1]

"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27184 / PCC 6803 / N-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000022 Genomic DNA. Translation: BAA17908.1.
PIR	S75046.
RefSeq	NP_441228.1. NC_000911.1.
3D structure databases
ProteinModelPortal	P73849.
ModBase	Search...
Protein-protein interaction databases
STRING	P73849.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	954570.
GenomeReviews	Gene locus slr1718 in contig BA000022_GR.
KEGG	syn:slr1718.
NMPDR	fig|1148.1.peg.1329.
PATRIC	23839796. VBISynSp132158_1459.
Phylogenomic databases
eggNOG	COG2045.
HOGENOM	HBG633644.
OMA	DFICSGY.
PhylomeDB	P73849.
ProtClustDB	PRK00886.
Enzyme and pathway databases
BioCyc	SSP1148:SLR1718-MONOMER.
Family and domain databases
HAMAP	MF_00490. ComB. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. IPR022995. Pase_ComB. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
KO	K05979.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
SUPFAM	SSF142823. SSF142823. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COMB_SYNY3

Accession

Primary (citable) accession number: P73849

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 5, 2001
Last sequence update:	February 1, 1997
Last modified:	January 25, 2012
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program