ID   P73774_SYNY3            Unreviewed;       335 AA.
AC   P73774;
DT   01-FEB-1997, integrated into UniProtKB/TrEMBL.
DT   01-FEB-1997, sequence version 1.
DT   27-MAR-2024, entry version 141.
DE   SubName: Full=Adenylate cyclase {ECO:0000313|EMBL:BAA17826.1};
GN   OrderedLocusNames=sll1161 {ECO:0000313|EMBL:BAA17826.1};
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Merismopediaceae;
OC   Synechocystis.
OX   NCBI_TaxID=1111708 {ECO:0000313|EMBL:BAA17826.1, ECO:0000313|Proteomes:UP000001425};
RN   [1] {ECO:0000313|EMBL:BAA17826.1, ECO:0000313|Proteomes:UP000001425}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa {ECO:0000313|Proteomes:UP000001425};
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
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DR   EMBL; BA000022; BAA17826.1; -; Genomic_DNA.
DR   PIR; S74865; S74865.
DR   AlphaFoldDB; P73774; -.
DR   STRING; 1148.gene:10498694; -.
DR   PaxDb; 1148-1652908; -.
DR   EnsemblBacteria; BAA17826; BAA17826; BAA17826.
DR   KEGG; syn:sll1161; -.
DR   eggNOG; COG0633; Bacteria.
DR   eggNOG; COG2114; Bacteria.
DR   InParanoid; P73774; -.
DR   PhylomeDB; P73774; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   CDD; cd00207; fer2; 1.
DR   Gene3D; 3.10.20.30; -; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR   InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR012675; Beta-grasp_dom_sf.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43644; NA(+)-TRANSLOCATING NADH-QUINONE REDUCTASE SUBUNIT; 1.
DR   PANTHER; PTHR43644:SF1; NAD(P)H-FLAVIN REDUCTASE; 1.
DR   Pfam; PF00111; Fer2; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF54292; 2Fe-2S ferredoxin-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS51085; 2FE2S_FER_2; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   FAD {ECO:0000256|ARBA:ARBA00022827};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001425}.
FT   DOMAIN          6..99
FT                   /note="2Fe-2S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51085"
FT   DOMAIN          122..254
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
SQ   SEQUENCE   335 AA;  37099 MW;  1ABFA21E18B6BC91 CRC64;
     MNKVPTLICL PDNRLLEIDS NETILDALLK GDIAHISVCG GKANCSTCRI MVLDGIKNCS
     PPTSIEQALA KKLDFPFHVR LACQTKLSNS ATIRRLVLDE GDIDLIDHQL TTGAINTERN
     VALLMANIRG ATNFDEVNFP YDIVYVMGRY FSQMQKIIEK YGGTISNVMG RKMLVAFGLK
     EFDVSAAERA TWAALEMFKS VQELNTLLNQ MRYRPLNLSM GIHSGSVVFV PLVAAQSTLL
     TPLGEVAAIV NLLESANKLK GTQLLVSQDV YQVIKNQARV GNQIILKEKE TTLQAYEILA
     MQGTPPIIED VEVVPRRQRL LTFVKKFAGS WLKSS
//