P73737 (MURI_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutamate racemase
EC=5.1.1.3

Gene names

Name:	murI
Ordered Locus Names:	slr1746

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa)

Taxonomic identifier

1111708 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechocystis

Protein attributes

Sequence length	279 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Provides the (R)-glutamate required for cell wall biosynthesis By similarity. HAMAP MF_00258
Catalytic activity	L-glutamate = D-glutamate. HAMAP MF_00258
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258
Sequence similarities	Belongs to the aspartate/glutamate racemases family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Molecular function	Isomerase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glutamate racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 279	279	Glutamate racemase HAMAP MF_00258		PRO_0000095525

Sequences

	Sequence		Length	Mass (Da)
	P73737 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: F8EB4A949B406392	FASTA	279	31,274
	10 20 30 40 50 60 MREPQRSRIG VFDSGVGGLT VLRELYRQLP KESILYFGDT ARLPYGKRSP QVILQYVREI 70 80 90 100 110 120 LTWMAAEEVK MVIMACNTSS ALALETVQQE FNMPILGVIL PGARAAVRQG RRIGVISTPA 130 140 150 160 170 180 TAASNAYRHA IHEITPDALV WQMACPEFVP LIEQNRLHDP YTLEVAKGYL QPLLDADIDT 190 200 210 220 230 240 LVFGCTHYRH LTPVFQQILP SHIRLVDPAS HVVKAARQEL EVMGLRNSEM SIATRFTVSG 250 260 270 CPQQFAELSH QWLGFTPMVE KISLPCLSSI CPQPLEIRE

References

[1]

"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27184 / PCC 6803 / N-1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000022 Genomic DNA. Translation: BAA17785.1.
PIR	S74824.
RefSeq	NP_441105.1. NC_000911.1.
3D structure databases
ProteinModelPortal	P73737.
ModBase	Search...
Protein-protein interaction databases
STRING	P73737.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	954419.
GenomeReviews	Gene locus slr1746 in contig BA000022_GR.
KEGG	syn:slr1746.
NMPDR	fig|1148.1.peg.1206.
PATRIC	23839510. VBISynSp132158_1318.
Phylogenomic databases
eggNOG	COG0796.
HOGENOM	HBG645102.
OMA	PQEDTIY.
PhylomeDB	P73737.
ProtClustDB	PRK00865.
Enzyme and pathway databases
BioCyc	SSP1148:SLR1746-MONOMER.
Family and domain databases
HAMAP	MF_00258. Glu_racemase. [Tree]
InterPro	IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR018187. Asp/Glu_racemase_AS. IPR004391. Glu_race. [Graphical view]
Gene3D	G3DSA:3.40.50.1860. Asp/Glu_race. 1 hit.
KO	K01776.
PANTHER	PTHR21198. PTHR21198. 1 hit.
Pfam	PF01177. Asp_Glu_race. 1 hit. [Graphical view]
SUPFAM	SSF53681. Asp/Glu_race. 2 hits.
TIGRFAMs	TIGR00067. Glut_race. 1 hit.
PROSITE	PS00923. ASP_GLU_RACEMASE_1. 1 hit. PS00924. ASP_GLU_RACEMASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MURI_SYNY3

Accession

Primary (citable) accession number: P73737

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	January 25, 2012
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program