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Protein

Site-specific DNA-methyltransferase (adenine-specific)

Gene

mbpA

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei14 – 141S-adenosyl-L-methionineUniRule annotation
Binding sitei18 – 181S-adenosyl-L-methionine; via amide nitrogenUniRule annotation
Binding sitei69 – 691S-adenosyl-L-methionineUniRule annotation
Binding sitei212 – 2121S-adenosyl-L-methionineUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineUniRule annotation

Protein family/group databases

REBASEi4496. M.Ssp6803III.

Names & Taxonomyi

Protein namesi
Recommended name:
Site-specific DNA-methyltransferase (adenine-specific)UniRule annotation (EC:2.1.1.72UniRule annotation)
Gene namesi
Name:mbpAImported
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)Imported
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
Proteomesi
  • UP000001425 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

IntActiP73682. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliP73682.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the N(4)/N(6)-methyltransferase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000281350.
InParanoidiP73682.
KOiK06223.
OMAiMNRHGFN.
PhylomeDBiP73682.

Family and domain databases

Gene3Di1.10.1020.10. 1 hit.
3.40.50.150. 2 hits.
InterProiIPR023095. Ade_MeTrfase_dom_2.
IPR002052. DNA_methylase_N6_adenine_CS.
IPR012263. M_m6A_EcoRV.
IPR012327. MeTrfase_D12.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF02086. MethyltransfD12. 1 hit.
[Graphical view]
PIRSFiPIRSF000398. M_m6A_EcoRV. 1 hit.
PRINTSiPR00505. D12N6MTFRASE.
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00571. dam. 1 hit.
PROSITEiPS00092. N6_MTASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P73682-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIKQAIAKP FLKWAGGKGK LIEQLVNCFP LEITTGQLTK YAEPFIGGGA
60 70 80 90 100
LYFHVAQNYP QIEKFFISDC NQQLVLAYQT IQQNVDDLID FLRRLQQKYY
110 120 130 140 150
CFNQDERKDF FYQQRLKFNQ NVTGINLEKF SKLWIEQTGL LIFLNRTCFN
160 170 180 190 200
GLFRVNSKGE FNVPFGDYKN PKICDAENLK LVANLLARTE IRFGDFTSSN
210 220 230 240 250
NFIDASTFVY FDPPYRPLNK TSSFNSYGKA NFNDNEQLRL AEYYQSLNNK
260 270 280 290 300
NAKLMLSNSD PKNINSDDNF FDDLYRGFQI ARIDALRMIN SQADKRGAIK

EILVVNYHR
Length:309
Mass (Da):35,977
Last modified:February 1, 1997 - v1
Checksum:iADF9F51D2215E12F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA17728.1.
PIRiS77170.

Genome annotation databases

EnsemblBacteriaiBAA17728; BAA17728; BAA17728.
KEGGisyn:slr1803.
PATRICi23839386. VBISynSp132158_1257.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA17728.1.
PIRiS77170.

3D structure databases

ProteinModelPortaliP73682.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP73682. 1 interaction.

Protein family/group databases

REBASEi4496. M.Ssp6803III.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA17728; BAA17728; BAA17728.
KEGGisyn:slr1803.
PATRICi23839386. VBISynSp132158_1257.

Phylogenomic databases

HOGENOMiHOG000281350.
InParanoidiP73682.
KOiK06223.
OMAiMNRHGFN.
PhylomeDBiP73682.

Family and domain databases

Gene3Di1.10.1020.10. 1 hit.
3.40.50.150. 2 hits.
InterProiIPR023095. Ade_MeTrfase_dom_2.
IPR002052. DNA_methylase_N6_adenine_CS.
IPR012263. M_m6A_EcoRV.
IPR012327. MeTrfase_D12.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF02086. MethyltransfD12. 1 hit.
[Graphical view]
PIRSFiPIRSF000398. M_m6A_EcoRV. 1 hit.
PRINTSiPR00505. D12N6MTFRASE.
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00571. dam. 1 hit.
PROSITEiPS00092. N6_MTASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / KazusaImported.

Entry informationi

Entry nameiP73682_SYNY3
AccessioniPrimary (citable) accession number: P73682
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: March 16, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.