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Protein

Phosphate acetyltransferase

Gene

pta

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Involved in acetate metabolism.By similarity

Catalytic activityi

Acetyl-CoA + phosphate = CoA + acetyl phosphate.

Pathwayi: acetyl-CoA biosynthesis

This protein is involved in step 2 of the subpathway that synthesizes acetyl-CoA from acetate.
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. Acetate kinase (ackA)
  2. Phosphate acetyltransferase (pta)
This subpathway is part of the pathway acetyl-CoA biosynthesis, which is itself part of Metabolic intermediate biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes acetyl-CoA from acetate, the pathway acetyl-CoA biosynthesis and in Metabolic intermediate biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

UniPathwayiUPA00340; UER00459

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphate acetyltransferase (EC:2.3.1.8)
Alternative name(s):
Phosphotransacetylase
Gene namesi
Name:pta
Ordered Locus Names:slr2132
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesMerismopediaceaeSynechocystis
Proteomesi
  • UP000001425 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001791481 – 697Phosphate acetyltransferaseAdd BLAST697

Proteomic databases

PaxDbiP73662
PRIDEiP73662

Interactioni

Protein-protein interaction databases

STRINGi1148.SYNGTS_1131

Structurei

3D structure databases

ProteinModelPortaliP73662
SMRiP73662
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni374 – 697Phosphate acetyltransferaseAdd BLAST324

Domaini

The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site (By similarity).By similarity

Sequence similaritiesi

In the N-terminal section; belongs to the CobB/CobQ family.Curated
In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.Curated

Phylogenomic databases

HOGENOMiHOG000053797
InParanoidiP73662
KOiK13788
OMAiTPLMFEY
PhylomeDBiP73662

Family and domain databases

Gene3Di3.40.1390.20, 1 hit
InterProiView protein in InterPro
IPR010766 DRTGG
IPR016475 P-Actrans_bac
IPR027417 P-loop_NTPase
IPR004614 P_AcTrfase
IPR002505 PTA_PTB
IPR028979 Ser_kin/Pase_Hpr-like_N_sf
PfamiView protein in Pfam
PF07085 DRTGG, 1 hit
PF01515 PTA_PTB, 1 hit
PIRSFiPIRSF006107 PhpActrans_proteobac, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF75138 SSF75138, 1 hit
TIGRFAMsiTIGR00651 pta, 1 hit

Sequencei

Sequence statusi: Complete.

P73662-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSSLYLSTT EARSGKSLVV LGILDLILKK TTRIAYFRPI IQDPVNGKHD
60 70 80 90 100
NNIILVLENF RLQQTYTDSF GLYFHEAVSL ASDGAIDQVL DRILAKYRHL
110 120 130 140 150
ADQVDFILCE GSDYLGEESA FEFDLNTTIA KMLNCPILLL GNAMGNTIAD
160 170 180 190 200
SLQPIDMALN SYDQESCQVV GVIINRVQPE LATEIQAQLE QRYGDRPMVL
210 220 230 240 250
GTIPQDIMLK SLRLREIVSG LNAQVLSGAD LLDNLVYHHL VVAMHIAHAL
260 270 280 290 300
HWLHEKNTLI ITPGDRGDII LGVMQAHRSL NYPSIAGILL TADYHPEPAI
310 320 330 340 350
MKLIEGLPDA PPLLLTSTHT HETSARLETL HPALSPTDNY KIRHSIALFQ
360 370 380 390 400
QQIDGEKLLN YLKTIRSKGI TPKLFLYNLV QAATAAQRHI VLPEGEEIRI
410 420 430 440 450
LKAAASLINH GIVRLTLLGN IEAIEQTVKI NHIDLDLSKV RLINPKTSPD
460 470 480 490 500
RERYAETYYQ LRKHKGVTLA MARDILTDIS YFGTMMVHLG EADGMVSGSV
510 520 530 540 550
NTTQHTVRPA LQIIKTQPGF SLVSSVFFMC LEDRVLVYGD CAVNPDPNAE
560 570 580 590 600
QLAEIALTSA ATAKNFGIEP RVALLSYSSG SSGQGADVEK VRQATAIAKE
610 620 630 640 650
REPDLALEGP IQYDAAVDST VAAQKMPGSA VAGKATVFIF PDLNTGNNTY
660 670 680 690
KAVQRETKAI AIGPILQGLN KPVNDLSRGC LVEDIINTVV ITALQVK
Length:697
Mass (Da):76,477
Last modified:February 1, 1997 - v1
Checksum:iF77B4439F5DB671A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA Translation: BAA17707.1
PIRiS77149

Genome annotation databases

EnsemblBacteriaiBAA17707; BAA17707; BAA17707
KEGGisyn:slr2132

Similar proteinsi

Entry informationi

Entry nameiPTA_SYNY3
AccessioniPrimary (citable) accession number: P73662
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: February 1, 1997
Last modified: March 28, 2018
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health