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P73662 (PTA_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 92. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphate acetyltransferase

EC=2.3.1.8
Alternative name(s):
Phosphotransacetylase
Gene names
Name:pta
Ordered Locus Names:slr2132
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length697 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in acetate metabolism By similarity.

Catalytic activity

Acetyl-CoA + phosphate = CoA + acetyl phosphate.

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.

Subcellular location

Cytoplasm Potential.

Domain

The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site By similarity.

Sequence similarities

In the N-terminal section; belongs to the CobB/CobQ family.

In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processacetyl-CoA biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionphosphate acetyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 697697Phosphate acetyltransferase
PRO_0000179148

Regions

Region374 – 697324Phosphate acetyltransferase

Sequences

Sequence LengthMass (Da)Tools
P73662 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: F77B4439F5DB671A

FASTA69776,477
        10         20         30         40         50         60 
MTSSLYLSTT EARSGKSLVV LGILDLILKK TTRIAYFRPI IQDPVNGKHD NNIILVLENF 

        70         80         90        100        110        120 
RLQQTYTDSF GLYFHEAVSL ASDGAIDQVL DRILAKYRHL ADQVDFILCE GSDYLGEESA 

       130        140        150        160        170        180 
FEFDLNTTIA KMLNCPILLL GNAMGNTIAD SLQPIDMALN SYDQESCQVV GVIINRVQPE 

       190        200        210        220        230        240 
LATEIQAQLE QRYGDRPMVL GTIPQDIMLK SLRLREIVSG LNAQVLSGAD LLDNLVYHHL 

       250        260        270        280        290        300 
VVAMHIAHAL HWLHEKNTLI ITPGDRGDII LGVMQAHRSL NYPSIAGILL TADYHPEPAI 

       310        320        330        340        350        360 
MKLIEGLPDA PPLLLTSTHT HETSARLETL HPALSPTDNY KIRHSIALFQ QQIDGEKLLN 

       370        380        390        400        410        420 
YLKTIRSKGI TPKLFLYNLV QAATAAQRHI VLPEGEEIRI LKAAASLINH GIVRLTLLGN 

       430        440        450        460        470        480 
IEAIEQTVKI NHIDLDLSKV RLINPKTSPD RERYAETYYQ LRKHKGVTLA MARDILTDIS 

       490        500        510        520        530        540 
YFGTMMVHLG EADGMVSGSV NTTQHTVRPA LQIIKTQPGF SLVSSVFFMC LEDRVLVYGD 

       550        560        570        580        590        600 
CAVNPDPNAE QLAEIALTSA ATAKNFGIEP RVALLSYSSG SSGQGADVEK VRQATAIAKE 

       610        620        630        640        650        660 
REPDLALEGP IQYDAAVDST VAAQKMPGSA VAGKATVFIF PDLNTGNNTY KAVQRETKAI 

       670        680        690 
AIGPILQGLN KPVNDLSRGC LVEDIINTVV ITALQVK 

« Hide

References

[1]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000022 Genomic DNA. Translation: BAA17707.1.
PIRS77149.
RefSeqNP_441027.1. NC_000911.1.
YP_005651084.1. NC_017277.1.
YP_007450909.1. NC_020286.1.

3D structure databases

ProteinModelPortalP73662.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING1148.slr2132.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA17707; BAA17707; BAA17707.
GeneID12255330.
14616563.
954340.
KEGGsyn:slr2132.
syy:SYNGTS_1131.
syz:MYO_111410.
PATRIC23839344. VBISynSp132158_1236.

Phylogenomic databases

eggNOGCOG0280.
HOGENOMHOG000053797.
KOK13788.
OMAVTPLMFE.
OrthoDBEOG6BKJ5W.
PhylomeDBP73662.
ProtClustDBPRK05632.

Enzyme and pathway databases

UniPathwayUPA00340; UER00459.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
InterProIPR010766. DRTGG.
IPR016475. P-Actrans_bac.
IPR027417. P-loop_NTPase.
IPR004614. P_AcTrfase.
IPR002505. PTA_PTB.
[Graphical view]
PfamPF07085. DRTGG. 1 hit.
PF01515. PTA_PTB. 1 hit.
[Graphical view]
PIRSFPIRSF006107. PhpActrans_proteobac. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00651. pta. 1 hit.
ProtoNetSearch...

Entry information

Entry namePTA_SYNY3
AccessionPrimary (citable) accession number: P73662
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: February 1, 1997
Last modified: April 16, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways