P73662 (PTA_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphate acetyltransferase
EC=2.3.1.8

Alternative name(s):
Phosphotransacetylase

Gene names

Name:	pta
Ordered Locus Names:	slr2132

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa)

Taxonomic identifier

1111708 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechocystis

Protein attributes

Sequence length	697 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in acetate metabolism By similarity.
Catalytic activity	Acetyl-CoA + phosphate = CoA + acetyl phosphate.
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.
Subcellular location	Cytoplasm Potential.
Domain	The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site By similarity.
Sequence similarities	In the N-terminal section; belongs to the CobB/CobQ family. In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	phosphate acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 697	697	Phosphate acetyltransferase		PRO_0000179148
Regions
	Region	374 – 697	324	Phosphate acetyltransferase

Sequences

	Sequence		Length	Mass (Da)
	P73662 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: F77B4439F5DB671A	FASTA	697	76,477
	10 20 30 40 50 60 MTSSLYLSTT EARSGKSLVV LGILDLILKK TTRIAYFRPI IQDPVNGKHD NNIILVLENF 70 80 90 100 110 120 RLQQTYTDSF GLYFHEAVSL ASDGAIDQVL DRILAKYRHL ADQVDFILCE GSDYLGEESA 130 140 150 160 170 180 FEFDLNTTIA KMLNCPILLL GNAMGNTIAD SLQPIDMALN SYDQESCQVV GVIINRVQPE 190 200 210 220 230 240 LATEIQAQLE QRYGDRPMVL GTIPQDIMLK SLRLREIVSG LNAQVLSGAD LLDNLVYHHL 250 260 270 280 290 300 VVAMHIAHAL HWLHEKNTLI ITPGDRGDII LGVMQAHRSL NYPSIAGILL TADYHPEPAI 310 320 330 340 350 360 MKLIEGLPDA PPLLLTSTHT HETSARLETL HPALSPTDNY KIRHSIALFQ QQIDGEKLLN 370 380 390 400 410 420 YLKTIRSKGI TPKLFLYNLV QAATAAQRHI VLPEGEEIRI LKAAASLINH GIVRLTLLGN 430 440 450 460 470 480 IEAIEQTVKI NHIDLDLSKV RLINPKTSPD RERYAETYYQ LRKHKGVTLA MARDILTDIS 490 500 510 520 530 540 YFGTMMVHLG EADGMVSGSV NTTQHTVRPA LQIIKTQPGF SLVSSVFFMC LEDRVLVYGD 550 560 570 580 590 600 CAVNPDPNAE QLAEIALTSA ATAKNFGIEP RVALLSYSSG SSGQGADVEK VRQATAIAKE 610 620 630 640 650 660 REPDLALEGP IQYDAAVDST VAAQKMPGSA VAGKATVFIF PDLNTGNNTY KAVQRETKAI 670 680 690 AIGPILQGLN KPVNDLSRGC LVEDIINTVV ITALQVK

References

[1]

"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27184 / PCC 6803 / N-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000022 Genomic DNA. Translation: BAA17707.1.
PIR	S77149.
RefSeq	NP_441027.1. NC_000911.1.
3D structure databases
ProteinModelPortal	P73662.
ModBase	Search...
Protein-protein interaction databases
STRING	P73662.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	954340.
GenomeReviews	Gene locus slr2132 in contig BA000022_GR.
KEGG	syn:slr2132.
NMPDR	fig|1148.1.peg.1128.
PATRIC	23839344. VBISynSp132158_1236.
Phylogenomic databases
eggNOG	COG0857.
HOGENOM	HBG576804.
OMA	VTPLMFE.
PhylomeDB	P73662.
ProtClustDB	PRK05632.
Enzyme and pathway databases
BioCyc	SSP1148:SLR2132-MONOMER.
Family and domain databases
InterPro	IPR002586. CbiA_P_synth. IPR010766. DRTGG. IPR016475. P-Actrans_bac. IPR004614. P_AcTrfase. IPR002505. PTA_PTB. [Graphical view]
KO	K13788.
Pfam	PF01656. CbiA. 1 hit. PF07085. DRTGG. 1 hit. PF01515. PTA_PTB. 1 hit. [Graphical view]
PIRSF	PIRSF006107. PhpActrans_proteobac. 1 hit.
TIGRFAMs	TIGR00651. Pta. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PTA_SYNY3

Accession

Primary (citable) accession number: P73662

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	February 1, 1997
Last modified:	January 25, 2012
This is version 76 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program