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Protein

UvrABC system protein C

Gene

uvrC

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

Miscellaneous

This bacterium is considerably more resistant to UV and gamma irradiation than E.coli; the E.coli-like SOS regulon model is not an appropriate model for DNA repair in this cyanobacterium.1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nuclease
Biological processDNA damage, DNA excision, DNA repair

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:sll0865
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesMerismopediaceaeSynechocystis
Proteomesi

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001383531 – 626UvrABC system protein CAdd BLAST626

Proteomic databases

PaxDbiP73580
PRIDEiP73580

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotation

Protein-protein interaction databases

IntActiP73580, 31 interactors
STRINGi1148.SYNGTS_1046

Structurei

3D structure databases

ProteinModelPortaliP73580
SMRiP73580
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 105GIY-YIGUniRule annotationAdd BLAST80
Domaini215 – 250UVRUniRule annotationAdd BLAST36

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000279960
InParanoidiP73580
KOiK03703
OMAiLFPIRQC
PhylomeDBiP73580

Family and domain databases

Gene3Di3.30.420.340, 1 hit
3.40.1440.10, 1 hit
HAMAPiMF_00203 UvrC, 1 hit
InterProiView protein in InterPro
IPR000305 GIY-YIG_endonuc
IPR035901 GIY-YIG_endonuc_sf
IPR003583 Hlx-hairpin-Hlx_DNA-bd_motif
IPR010994 RuvA_2-like
IPR001943 UVR_dom
IPR036876 UVR_dom_sf
IPR004791 UvrC
IPR001162 UvrC_homol_region
IPR038476 UvrC_homol_region_sf
PfamiView protein in Pfam
PF01541 GIY-YIG, 1 hit
PF02151 UVR, 1 hit
PF08459 UvrC_HhH_N, 1 hit
SMARTiView protein in SMART
SM00465 GIYc, 1 hit
SM00278 HhH1, 2 hits
SUPFAMiSSF46600 SSF46600, 1 hit
SSF47781 SSF47781, 1 hit
SSF82771 SSF82771, 1 hit
TIGRFAMsiTIGR00194 uvrC, 1 hit
PROSITEiView protein in PROSITE
PS50164 GIY_YIG, 1 hit
PS50151 UVR, 1 hit
PS50165 UVRC, 1 hit

Sequencei

Sequence statusi: Complete.

P73580-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVATVSSTSL LEQPELLERR LQEIPQEPGV YFMGDRQGEI LYIGKAKKLR
60 70 80 90 100
TRVRSYFRDS QPHTARIALM VQQVAEIEFI VTDTEAEALA LEANLIKQHQ
110 120 130 140 150
PHFNVLLKDD KKYPYVCITW SETYPRIFIT RKRRLNQAKD RYYGPYVDSF
160 170 180 190 200
SLRQTLRLIQ RIFPLRQRRQ PLFKHRPCLN YDIGRCPGVC QELITPEDYR
210 220 230 240 250
QTLQKVAMVF QGRTQELHQL LTQQMEKAAA DLKFEQAALI RDQINSLGKL
260 270 280 290 300
NADQKVSLPQ DTISRDAIAV ASDGQISAIQ LFQIRAGRLV GRLGFFADGV
310 320 330 340 350
ESELEKGEVL QRVLEQHYQQ VEAVEIPSEV ILPCALPDGE LLNDWLTSQR
360 370 380 390 400
GRKVTFNLPQ RQTKAELLEM VERNAQYELE RLQKQTAKNV TALEDLAEIL
410 420 430 440 450
NLETLPKRIE GYDISHIQGS NAVASQVVFI DGVPAQQYYR HYKIKNPSIK
460 470 480 490 500
VGHSDDFASL AEVIIRRFQS SVKGKKNQQD WPDLIMIDGG KGQLSAVVKV
510 520 530 540 550
LKKMDLLDKF TVVSLAKQRE EIFLPGESQP LPTHAEQPGV QLLRRLRDEA
560 570 580 590 600
HRFAVSFHRQ QRLSKSRRSR LDEIPGLGFS RQKQLLAHFR SLDYIREASV
610 620
KQLQEVPGIG PQLAQTIYDY FHPVNS
Length:626
Mass (Da):71,897
Last modified:February 1, 1997 - v1
Checksum:i9D7E9627F0A645DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA Translation: BAA17620.1
PIRiS77286

Genome annotation databases

EnsemblBacteriaiBAA17620; BAA17620; BAA17620
KEGGisyn:sll0865

Similar proteinsi

Entry informationi

Entry nameiUVRC_SYNY3
AccessioniPrimary (citable) accession number: P73580
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: May 23, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

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