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P73574

- FABG1_SYNY3

UniProt

P73574 - FABG1_SYNY3

Protein

3-oxoacyl-[acyl-carrier-protein] reductase 1

Gene

fabG1

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 95 (01 Oct 2014)
      Sequence version 1 (01 Feb 1997)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    (3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP+ = 3-oxoacyl-[acyl-carrier-protein] + NADPH.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei143 – 1431SubstrateBy similarity
    Active sitei156 – 1561Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi11 – 3525NADPBy similarityAdd
    BLAST

    GO - Molecular functioni

    1. 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity Source: UniProtKB-EC
    2. NAD binding Source: InterPro

    GO - Biological processi

    1. fatty acid biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

    Keywords - Ligandi

    NADP

    Enzyme and pathway databases

    UniPathwayiUPA00094.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    3-oxoacyl-[acyl-carrier-protein] reductase 1 (EC:1.1.1.100)
    Alternative name(s):
    3-ketoacyl-acyl carrier protein reductase 1
    Gene namesi
    Name:fabG1
    Ordered Locus Names:slr0886
    OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
    Taxonomic identifieri1111708 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
    ProteomesiUP000001425: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 2472473-oxoacyl-[acyl-carrier-protein] reductase 1PRO_0000054691Add
    BLAST

    Proteomic databases

    PaxDbiP73574.

    Interactioni

    Protein-protein interaction databases

    IntActiP73574. 1 interaction.
    STRINGi1148.slr0886.

    Structurei

    3D structure databases

    ProteinModelPortaliP73574.
    SMRiP73574. Positions 4-246.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG1028.
    KOiK00059.
    OMAiEGTTANC.
    OrthoDBiEOG6N3CR8.
    PhylomeDBiP73574.

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    InterProiIPR011284. 3oxo_ACP_reduc.
    IPR002198. DH_sc/Rdtase_SDR.
    IPR002347. Glc/ribitol_DH.
    IPR016040. NAD(P)-bd_dom.
    IPR020904. Sc_DH/Rdtase_CS.
    [Graphical view]
    PfamiPF00106. adh_short. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000126. 11-beta-HSD1. 1 hit.
    PRINTSiPR00081. GDHRDH.
    PR00080. SDRFAMILY.
    TIGRFAMsiTIGR01830. 3oxo_ACP_reduc. 1 hit.
    PROSITEiPS00061. ADH_SHORT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P73574-1 [UniParc]FASTAAdd to Basket

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    MTALTAQVAL VTGASRGIGK ATALALAATG MKVVVNYAQS STAADAVVAE    50
    IIANGGEAIA VQANVANADE VDQLIKTTLD KFSRIDVLVN NAGITRDTLL 100
    LRMKLEDWQA VIDLNLTGVF LCTKAVSKLM LKQKSGRIIN ITSVAGMMGN 150
    PGQANYSAAK AGVIGFTKTV AKELASRGVT VNAVAPGFIA TDMTENLNAE 200
    PILQFIPLAR YGQPEEVAGT IRFLATDPAA AYITGQTFNV DGGMVMF 247
    Length:247
    Mass (Da):25,724
    Last modified:February 1, 1997 - v1
    Checksum:i91EBF9409C777F20
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000022 Genomic DNA. Translation: BAA17614.1.
    PIRiS77280.
    RefSeqiNP_440934.1. NC_000911.1.
    YP_005650993.1. NC_017277.1.
    YP_007450817.1. NC_020286.1.

    Genome annotation databases

    EnsemblBacteriaiBAA17614; BAA17614; BAA17614.
    GeneIDi954241.
    KEGGisyn:slr0886.
    syy:SYNGTS_1040.
    syz:MYO_110490.
    PATRICi23839140. VBISynSp132158_1134.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000022 Genomic DNA. Translation: BAA17614.1 .
    PIRi S77280.
    RefSeqi NP_440934.1. NC_000911.1.
    YP_005650993.1. NC_017277.1.
    YP_007450817.1. NC_020286.1.

    3D structure databases

    ProteinModelPortali P73574.
    SMRi P73574. Positions 4-246.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P73574. 1 interaction.
    STRINGi 1148.slr0886.

    Proteomic databases

    PaxDbi P73574.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAA17614 ; BAA17614 ; BAA17614 .
    GeneIDi 954241.
    KEGGi syn:slr0886.
    syy:SYNGTS_1040.
    syz:MYO_110490.
    PATRICi 23839140. VBISynSp132158_1134.

    Phylogenomic databases

    eggNOGi COG1028.
    KOi K00059.
    OMAi EGTTANC.
    OrthoDBi EOG6N3CR8.
    PhylomeDBi P73574.

    Enzyme and pathway databases

    UniPathwayi UPA00094 .

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    InterProi IPR011284. 3oxo_ACP_reduc.
    IPR002198. DH_sc/Rdtase_SDR.
    IPR002347. Glc/ribitol_DH.
    IPR016040. NAD(P)-bd_dom.
    IPR020904. Sc_DH/Rdtase_CS.
    [Graphical view ]
    Pfami PF00106. adh_short. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000126. 11-beta-HSD1. 1 hit.
    PRINTSi PR00081. GDHRDH.
    PR00080. SDRFAMILY.
    TIGRFAMsi TIGR01830. 3oxo_ACP_reduc. 1 hit.
    PROSITEi PS00061. ADH_SHORT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
      Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
      , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
      DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PCC 6803 / Kazusa.

    Entry informationi

    Entry nameiFABG1_SYNY3
    AccessioniPrimary (citable) accession number: P73574
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 15, 1998
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 95 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families
    3. Synechocystis PCC 6803
      Synechocystis (strain PCC 6803): entries and gene names

    External Data

    Dasty 3