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P73574

- FABG1_SYNY3

UniProt

P73574 - FABG1_SYNY3

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Protein
3-oxoacyl-[acyl-carrier-protein] reductase 1
Gene
fabG1, slr0886
Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP+ = 3-oxoacyl-[acyl-carrier-protein] + NADPH.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei143 – 1431Substrate By similarity
Active sitei156 – 1561Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi11 – 3525NADP By similarity
Add
BLAST

GO - Molecular functioni

  1. 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity Source: UniProtKB-EC
  2. NAD binding Source: InterPro

GO - Biological processi

  1. fatty acid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Keywords - Ligandi

NADP

Enzyme and pathway databases

UniPathwayiUPA00094.

Names & Taxonomyi

Protein namesi
Recommended name:
3-oxoacyl-[acyl-carrier-protein] reductase 1 (EC:1.1.1.100)
Alternative name(s):
3-ketoacyl-acyl carrier protein reductase 1
Gene namesi
Name:fabG1
Ordered Locus Names:slr0886
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2472473-oxoacyl-[acyl-carrier-protein] reductase 1
PRO_0000054691Add
BLAST

Proteomic databases

PaxDbiP73574.

Interactioni

Protein-protein interaction databases

IntActiP73574. 1 interaction.
STRINGi1148.slr0886.

Structurei

3D structure databases

ProteinModelPortaliP73574.
SMRiP73574. Positions 4-246.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1028.
KOiK00059.
OMAiEGTTANC.
OrthoDBiEOG6N3CR8.
PhylomeDBiP73574.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR011284. 3oxo_ACP_reduc.
IPR002198. DH_sc/Rdtase_SDR.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
[Graphical view]
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PIRSFiPIRSF000126. 11-beta-HSD1. 1 hit.
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
TIGRFAMsiTIGR01830. 3oxo_ACP_reduc. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P73574-1 [UniParc]FASTAAdd to Basket

« Hide

MTALTAQVAL VTGASRGIGK ATALALAATG MKVVVNYAQS STAADAVVAE    50
IIANGGEAIA VQANVANADE VDQLIKTTLD KFSRIDVLVN NAGITRDTLL 100
LRMKLEDWQA VIDLNLTGVF LCTKAVSKLM LKQKSGRIIN ITSVAGMMGN 150
PGQANYSAAK AGVIGFTKTV AKELASRGVT VNAVAPGFIA TDMTENLNAE 200
PILQFIPLAR YGQPEEVAGT IRFLATDPAA AYITGQTFNV DGGMVMF 247
Length:247
Mass (Da):25,724
Last modified:February 1, 1997 - v1
Checksum:i91EBF9409C777F20
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000022 Genomic DNA. Translation: BAA17614.1.
PIRiS77280.
RefSeqiNP_440934.1. NC_000911.1.
YP_005650993.1. NC_017277.1.
YP_007450817.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA17614; BAA17614; BAA17614.
GeneIDi954241.
KEGGisyn:slr0886.
syy:SYNGTS_1040.
syz:MYO_110490.
PATRICi23839140. VBISynSp132158_1134.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000022 Genomic DNA. Translation: BAA17614.1 .
PIRi S77280.
RefSeqi NP_440934.1. NC_000911.1.
YP_005650993.1. NC_017277.1.
YP_007450817.1. NC_020286.1.

3D structure databases

ProteinModelPortali P73574.
SMRi P73574. Positions 4-246.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P73574. 1 interaction.
STRINGi 1148.slr0886.

Proteomic databases

PaxDbi P73574.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA17614 ; BAA17614 ; BAA17614 .
GeneIDi 954241.
KEGGi syn:slr0886.
syy:SYNGTS_1040.
syz:MYO_110490.
PATRICi 23839140. VBISynSp132158_1134.

Phylogenomic databases

eggNOGi COG1028.
KOi K00059.
OMAi EGTTANC.
OrthoDBi EOG6N3CR8.
PhylomeDBi P73574.

Enzyme and pathway databases

UniPathwayi UPA00094 .

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
InterProi IPR011284. 3oxo_ACP_reduc.
IPR002198. DH_sc/Rdtase_SDR.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
[Graphical view ]
Pfami PF00106. adh_short. 1 hit.
[Graphical view ]
PIRSFi PIRSF000126. 11-beta-HSD1. 1 hit.
PRINTSi PR00081. GDHRDH.
PR00080. SDRFAMILY.
TIGRFAMsi TIGR01830. 3oxo_ACP_reduc. 1 hit.
PROSITEi PS00061. ADH_SHORT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiFABG1_SYNY3
AccessioniPrimary (citable) accession number: P73574
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: February 1, 1997
Last modified: July 9, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
  3. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3

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