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P73560 (GCSH_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycine cleavage system H protein
Gene names
Name:gcvH
Ordered Locus Names:slr0879
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length132 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein By similarity. HAMAP-Rule MF_00272

Cofactor

Binds 1 lipoyl cofactor covalently By similarity. HAMAP-Rule MF_00272

Subunit structure

The glycine cleavage system is composed of four proteins: P, T, L and H By similarity.

Sequence similarities

Belongs to the GcvH family.

Contains 1 lipoyl-binding domain.

Ontologies

Keywords
   DomainLipoyl
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processglycine decarboxylation via glycine cleavage system

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentglycine cleavage complex

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 132132Glycine cleavage system H protein HAMAP-Rule MF_00272
PRO_0000166257

Amino acid modifications

Modified residue651N6-lipoyllysine By similarity

Sequences

Sequence LengthMass (Da)Tools
P73560 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 21F530DA4BB53DED

FASTA13214,580
        10         20         30         40         50         60 
MELEHPDDLY YLDSHEYVRF DGETATIGLS AFAVDELGDI VFVELPEEGD KVEFEQSMGA 

        70         80         90        100        110        120 
VESVKAASDL YSPVTGTVIE KNSALEDQPE LLNQDPYGEE GWLIKVRLDD VEDAKEGLMA 

       130 
AGDYRATLET GD 

« Hide

References

[1]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000022 Genomic DNA. Translation: BAA17600.1.
PIRS77266.
RefSeqNP_440920.1. NC_000911.1.
YP_005650979.1. NC_017277.1.
YP_007450803.1. NC_020286.1.

3D structure databases

ProteinModelPortalP73560.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING1148.slr0879.

Proteomic databases

PaxDbP73560.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA17600; BAA17600; BAA17600.
GeneID12255065.
14616457.
954225.
KEGGsyn:slr0879.
syy:SYNGTS_1026.
syz:MYO_110350.
PATRIC23839106. VBISynSp132158_1117.

Phylogenomic databases

eggNOGCOG0509.
HOGENOMHOG000239392.
KOK02437.
OMAMDESAYK.
OrthoDBEOG60CWTC.
PhylomeDBP73560.

Family and domain databases

HAMAPMF_00272. GcvH.
InterProIPR003016. 2-oxoA_DH_lipoyl-BS.
IPR002930. GCV_H.
IPR017453. GCV_H_sub.
IPR011053. Single_hybrid_motif.
[Graphical view]
PANTHERPTHR11715. PTHR11715. 1 hit.
PfamPF01597. GCV_H. 1 hit.
[Graphical view]
SUPFAMSSF51230. SSF51230. 1 hit.
TIGRFAMsTIGR00527. gcvH. 1 hit.
PROSITEPS00189. LIPOYL. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGCSH_SYNY3
AccessionPrimary (citable) accession number: P73560
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: February 1, 1997
Last modified: April 16, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families