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P73548

- CDSA_SYNY3

UniProt

P73548 - CDSA_SYNY3

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Protein

Phosphatidate cytidylyltransferase

Gene

cdsA

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

CTP + phosphatidate = diphosphate + CDP-diacylglycerol.

Pathwayi

GO - Molecular functioni

  1. phosphatidate cytidylyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Enzyme and pathway databases

UniPathwayiUPA00557; UER00614.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphatidate cytidylyltransferase (EC:2.7.7.41)
Alternative name(s):
CDP-DAG synthase
CDP-DG synthase
CDP-diacylglycerol synthase
Short name:
CDS
CDP-diglyceride pyrophosphorylase
CDP-diglyceride synthase
CTP:phosphatidate cytidylyltransferase
Gene namesi
Name:cdsA
Ordered Locus Names:slr1369
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425: Chromosome

Subcellular locationi

Cell membrane By similarity; Multi-pass membrane protein By similarity

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 293293Phosphatidate cytidylyltransferasePRO_0000090757Add
BLAST

Interactioni

Protein-protein interaction databases

IntActiP73548. 4 interactions.
STRINGi1148.slr1369.

Structurei

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei6 – 2621HelicalSequence AnalysisAdd
BLAST
Transmembranei51 – 7121HelicalSequence AnalysisAdd
BLAST
Transmembranei73 – 9321HelicalSequence AnalysisAdd
BLAST
Transmembranei97 – 11721HelicalSequence AnalysisAdd
BLAST
Transmembranei157 – 17721HelicalSequence AnalysisAdd
BLAST
Transmembranei195 – 21521HelicalSequence AnalysisAdd
BLAST
Transmembranei218 – 23821HelicalSequence AnalysisAdd
BLAST
Transmembranei273 – 29321HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the CDS family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0575.
HOGENOMiHOG000006169.
InParanoidiP73548.
KOiK00981.
OMAiLCIWAAD.
OrthoDBiEOG6TBHJT.
PhylomeDBiP73548.

Family and domain databases

InterProiIPR000374. PC_trans.
[Graphical view]
PfamiPF01148. CTP_transf_1. 1 hit.
[Graphical view]
PROSITEiPS01315. CDS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P73548 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPTQRIISAV IGIALAFSLL ILGGWYFSAA IALVIYLGLR EYFQMVRAKG
60 70 80 90 100
IAPAAKTTMV LSLMLLLSAT VTPHLTDAFF PLTGALICFY LLFQPKMATI
110 120 130 140 150
ADISTSLLGL FYGGYLPSYW VRLRLGDGAV NPMGLHLPLN GFWPESWAHP
160 170 180 190 200
ENFPTGLLVT ILAFACIWAA DIGAYIMGKW LGRTRLSDIS PKKTVEGSLW
210 220 230 240 250
GVGGSLLVGV LGAWYLQWPY WEITGALLGL LIGIVSLLGD LTESMMKRDA
260 270 280 290
GVKDSGQLIP GHGGILDRTD SYVFTAPLVY YFVVLLLPVL NNL
Length:293
Mass (Da):31,876
Last modified:February 1, 1997 - v1
Checksum:iA7E3ABC9C17475D0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000022 Genomic DNA. Translation: BAA17588.1.
PIRiS77254.
RefSeqiNP_440908.1. NC_000911.1.
YP_005650967.1. NC_017277.1.
YP_007450791.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA17588; BAA17588; BAA17588.
GeneIDi954211.
KEGGisyn:slr1369.
syy:SYNGTS_1014.
syz:MYO_110230.
PATRICi23839080. VBISynSp132158_1104.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000022 Genomic DNA. Translation: BAA17588.1 .
PIRi S77254.
RefSeqi NP_440908.1. NC_000911.1.
YP_005650967.1. NC_017277.1.
YP_007450791.1. NC_020286.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P73548. 4 interactions.
STRINGi 1148.slr1369.

Protocols and materials databases

DNASUi 954211.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA17588 ; BAA17588 ; BAA17588 .
GeneIDi 954211.
KEGGi syn:slr1369.
syy:SYNGTS_1014.
syz:MYO_110230.
PATRICi 23839080. VBISynSp132158_1104.

Phylogenomic databases

eggNOGi COG0575.
HOGENOMi HOG000006169.
InParanoidi P73548.
KOi K00981.
OMAi LCIWAAD.
OrthoDBi EOG6TBHJT.
PhylomeDBi P73548.

Enzyme and pathway databases

UniPathwayi UPA00557 ; UER00614 .

Family and domain databases

InterProi IPR000374. PC_trans.
[Graphical view ]
Pfami PF01148. CTP_transf_1. 1 hit.
[Graphical view ]
PROSITEi PS01315. CDS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiCDSA_SYNY3
AccessioniPrimary (citable) accession number: P73548
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: October 29, 2014
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
  3. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3