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P73515

- SPKE_SYNY3

UniProt

P73515 - SPKE_SYNY3

Protein

Serine/threonine-protein kinase-like protein E

Gene

spkE

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 96 (01 Oct 2014)
      Sequence version 1 (01 Feb 1997)
      Previous versions | rss
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    • Comment

    Functioni

    Lacks protein kinase activity.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei44 – 441Defective ATP-bindingBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi21 – 299ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. protein kinase activity Source: InterPro

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Serine/threonine-protein kinase-like protein E
    Gene namesi
    Name:spkE
    Ordered Locus Names:slr1443
    OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
    Taxonomic identifieri1111708 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
    ProteomesiUP000001425: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 614614Serine/threonine-protein kinase-like protein EPRO_0000171243Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    IntActiP73515. 4 interactions.
    STRINGi1148.slr1443.

    Structurei

    3D structure databases

    ProteinModelPortaliP73515.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini15 – 404390Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0515.
    KOiK08884.
    OMAiIAFELEL.
    OrthoDBiEOG63C0P6.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P73515-1 [UniParc]FASTAAdd to Basket

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    MTPSLSLGQR LDDRYLIQLH LGQNSLGQQY LAQDTHRFDE PCTITVLTAP    50
    PGDKAGNLFK QQAEILYALD HPQIANFREF FALGSELYLV QDFIEGQSYF 100
    DLLKDRRLQG KAFTELEVRQ WCRQLLPVLH YLHIQKICHG QISPSSIMRR 150
    TVDGLPVLVD FTHSQYYSGT PGEDRRDLHG LGLGAIALLT GEVNPNPPWE 200
    NLLSSVALSQ EFRQLLLKLL AWPPLVDWPT LTDNLNNLPQ HFLPTVAEFN 250
    LTSTIPEQTD NGVGKSSTGE PPFPTVHQSP ESSSSAKVKN MVRVDGLKGL 300
    VKKSFILLGL MAIAMALGWG AGQLWLDNQQ RAALEKLAQE EPGDDVPEKT 350
    DLEIKNEIRA RRLNLGISPQ RFQTLMDDGL AFQLGIDPQQ RLEKNPNTNG 400
    APLSLGSPEQ QMAMTITVLD ALESLSREAT RDFAQNNSGD RRRWIPRVNQ 450
    LRLSSRSFYD LVNARFHHYL PMVSPALLGE PEFEQRPLAQ VWNAMAFDSL 500
    ASLEDESHYQ RLSFDDTNQL NLNGTLEPGE GYAYAVTIPP TEEFSLQLTA 550
    PPTARISFYP PTGPEVILQN SAMHRWSGPT DQAGYYELVI TSVAEEPIAF 600
    ELELSIIPAS AQPF 614
    Length:614
    Mass (Da):68,700
    Last modified:February 1, 1997 - v1
    Checksum:i19B4F1DB691E96DB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB046602 Genomic DNA. Translation: BAB17038.1.
    BA000022 Genomic DNA. Translation: BAA17555.1.
    PIRiS77221.
    RefSeqiNP_440875.1. NC_000911.1.
    YP_005650934.1. NC_017277.1.
    YP_007450758.1. NC_020286.1.

    Genome annotation databases

    EnsemblBacteriaiBAA17555; BAA17555; BAA17555.
    GeneIDi954178.
    KEGGisyn:slr1443.
    syy:SYNGTS_0981.
    syz:MYO_19880.
    PATRICi23839000. VBISynSp132158_1065.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB046602 Genomic DNA. Translation: BAB17038.1 .
    BA000022 Genomic DNA. Translation: BAA17555.1 .
    PIRi S77221.
    RefSeqi NP_440875.1. NC_000911.1.
    YP_005650934.1. NC_017277.1.
    YP_007450758.1. NC_020286.1.

    3D structure databases

    ProteinModelPortali P73515.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P73515. 4 interactions.
    STRINGi 1148.slr1443.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAA17555 ; BAA17555 ; BAA17555 .
    GeneIDi 954178.
    KEGGi syn:slr1443.
    syy:SYNGTS_0981.
    syz:MYO_19880.
    PATRICi 23839000. VBISynSp132158_1065.

    Phylogenomic databases

    eggNOGi COG0515.
    KOi K08884.
    OMAi IAFELEL.
    OrthoDBi EOG63C0P6.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Biochemical examination of the potential eukaryotic-type protein kinase genes in the complete genome of the unicellular Cyanobacterium synechocystis sp. PCC 6803."
      Kamei A., Yuasa T., Geng X., Ikeuchi M.
      DNA Res. 9:71-78(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], LACK OF KINASE ACTIVITY.
    2. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
      Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
      , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
      DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PCC 6803 / Kazusa.

    Entry informationi

    Entry nameiSPKE_SYNY3
    AccessioniPrimary (citable) accession number: P73515
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 14, 2001
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 96 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Synechocystis PCC 6803
      Synechocystis (strain PCC 6803): entries and gene names

    External Data

    Dasty 3