Reviewed, UniProtKB/Swiss-Prot P73511 (PHSG_SYNY3)

Names and origin

Protein names

Recommended name:
    Glycogen phosphorylase
    EC=2.4.1.1

Gene names

Name:	glgP
Ordered Locus Names:	sll1356

Organism

Synechocystis sp. (strain PCC 6803) [Complete proteome] [HAMAP]

Taxonomic identifier

1148 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechocystis

Protein attributes

Sequence length	849 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties By similarity.
Catalytic activity	(1,4-alpha-D-glucosyl)(n) + phosphate = (1,4-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate.
Cofactor	Pyridoxal phosphate By similarity.
Sequence similarities	Belongs to the glycogen phosphorylase family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glycogen metabolism
Ligand	Pyridoxal phosphate
Molecular function	Glycosyltransferase Transferase
Technical term	Allosteric enzyme Complete proteome
Gene Ontology (GO)
Biological process	glycogen metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	phosphorylase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 849	849	Glycogen phosphorylase		PRO_0000188559
Amino acid modifications
	Modified residue	679	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	P73511-1 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 657D2C5E83C23A3D	FASTA	849	96,649
	10 20 30 40 50 60 MEHLPMAFNT TNPLIQVEDD RTGLSVETLK RALADNLFYL QGKFPAIATK NDCYMALAYT 70 80 90 100 110 120 IRDRLLQRWL NTFQTYLNCD NRVVCYLSAE YLLGPHLGNN LINLGLWEPV QQAVEESGLS 130 140 150 160 170 180 LDELIDIEEE PGLGNGGLGR LAACFMDSLA TLEIPAIGYG IRYEFGIFDQ EIKDGWQVEI 190 200 210 220 230 240 TDKWLQLGNP WEIARPESAV LVKLGGHTEP YTDDQGNYRV RWIAGSLVKG IPYDTPILGY 250 260 270 280 290 300 KVSTANNLRL WKSEAAESFD FQRFNVGDYY GAVQDKMSSE NLTKVLYPND EQIQGKELRL 310 320 330 340 350 360 AQQYFFVSCS LQDMIRIHLS DNPTLENFHE HFAVQMNDTH PSIAVAELMR LLVDEHHYEW 370 380 390 400 410 420 QRAWAITEAT FGFTNHTLLP EALEKWSLPL FGEMLPRHLE IIYEINQRFL DQVRMKYPND 430 440 450 460 470 480 GDRLARLSII DEAGEKSVRM AYLATVGSHA INGVAALHSQ LVKETILKDF YELWPEKFSN 490 500 510 520 530 540 KTNGVTPRRW MVLSNPRLSN LISSRIGDGW IKNLDELKQL EPFADLAGFR QDWCKVKREV 550 560 570 580 590 600 KQDLARYIHT RTDLVVNPDS LFDVQVKRIH EYKRQHLNIL HVIHLYLQIK NNPNLDVTPR 610 620 630 640 650 660 TFIYGGKAAP GYFTAKLIIK LINSVADVVN NDPTIGDRLK VIFLPDYNVK FGQRVYPAAD 670 680 690 700 710 720 LSEQISTAGK EASGTGNMKF SMNGALTIGT LDGANIEIRE EVGAENFFLF GLTTPEVEKT 730 740 750 760 770 780 LAEGYQPWEY YNNNANLKAV VDLINSGFFS HGDTALFRPL MDSLLGQDPY LVFADFQAYV 790 800 810 820 830 840 DCQNQVGEAY KDQENWARMA ILNVARMGKF SSDRTIREYA EDIWAIKPVV IELEDLCPDG QCLLISPNK

References

[1]

"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000022 Genomic DNA. Translation: BAA17551.1.
PIR	S77217.
RefSeq	NP_440871.1.
3D structure databases
HSSP	HSSP built from PDB template 1EM6 based on UniProtKB P06737.
ModBase	Search...
Protein-protein interaction databases
IntAct	P73511. 8 interactions.
STRING	P73511.
Protein family/group databases
CAZy	GT35. Glycosyltransferase Family 35.
Genome annotation databases
GeneID	954174.
GenomeReviews	Gene locus sll1356 in contig BA000022_GR.
KEGG	syn:sll1356.
NMPDR	fig|1148.1.peg.972.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P73511.
OMA	CYLSAEY.
Enzyme and pathway databases
BioCyc	SSP1148:SLL1356-MON.
Family and domain databases
InterPro	IPR011833. Glycg_phsphrylas. IPR000811. Glyco_trans_35. [Graphical view]
PANTHER	PTHR11468. Glyco_trans_35. 1 hit.
Pfam	PF00343. Phosphorylase. 1 hit. [Graphical view]
PIRSF	PIRSF000460. Pprylas_GlgP. 1 hit.
TIGRFAMs	TIGR02093. P_ylase. 1 hit.
PROSITE	PS00102. PHOSPHORYLASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PHSG_SYNY3

Accession

Primary (citable) accession number: P73511

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	February 1, 1997
Last modified:	November 3, 2009
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)