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Protein

DNA helicase

Gene

uvrD

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.SAAS annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. ATP-dependent DNA helicase activity Source: InterPro
  3. DNA binding Source: InterPro

GO - Biological processi

  1. DNA unwinding involved in DNA replication Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

HelicaseSAAS annotationImported, Hydrolase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA helicaseSAAS annotation (EC:3.6.4.12SAAS annotation)
Gene namesi
Name:uvrDImported
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)Imported
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiP73465.

Interactioni

Protein-protein interaction databases

IntActiP73465. 21 interactions.
STRINGi1148.sll1143.

Structurei

3D structure databases

ProteinModelPortaliP73465.
SMRiP73465. Positions 608-702.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0210.
HOGENOMiHOG000033016.
InParanoidiP73465.
KOiK03657.
OMAiVLMQNRI.
PhylomeDBiP73465.

Family and domain databases

Gene3Di1.10.10.160. 1 hit.
3.40.50.300. 4 hits.
InterProiIPR005751. ATP-dep_DNA_helicase_PcrA.
IPR013986. DExx_box_DNA_helicase_dom.
IPR014017. DNA_helicase_UvrD-like_C.
IPR000212. DNA_helicase_UvrD/REP.
IPR027417. P-loop_NTPase.
IPR014016. UvrD-like_ATP-bd.
[Graphical view]
PANTHERiPTHR11070. PTHR11070. 1 hit.
PfamiPF00580. UvrD-helicase. 1 hit.
PF13361. UvrD_C. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR01073. pcrA. 1 hit.
PROSITEiPS51198. UVRD_HELICASE_ATP_BIND. 1 hit.
PS51217. UVRD_HELICASE_CTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P73465-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPMTVVPDYL AHLNPSQRRA VEHFCGPLLV VAGAGSGKTR ALTYRIAHLI
60 70 80 90 100
RQHRINPENI LAVTFTNKAA KEMKERLEKI FAQAWAQQEF SQRWELLGKY
110 120 130 140 150
EQKQLLSRVY KTVTKPLWIG TFHSLCSRIL RYDIDKYQDS SGRRWTKQFS
160 170 180 190 200
IFDESDVQSL FKTIVTKDMD LDEKQFNPKS IRYQVSNAKN LGQSPETYLR
210 220 230 240 250
ENPSYKGRVI AEVYQAYQNQ LAANNALDFD DLILIPTRLF QQNESVLGYW
260 270 280 290 300
HRKFNHILVD EYQDTNRIQY DLIRLLSTNG EERQSEWDWR GRSTFVVGDA
310 320 330 340 350
DQSIYSFRMA DFTILLNFQE DFGDRLLDGE TTTMVKLEEN YRSRENILQA
360 370 380 390 400
ANHLIEHNSQ RIDKILKATR SGGDDIILYQ ADDERDESRF VINKILSLRK
410 420 430 440 450
NNPELNFGDF AILYRTNAQS RAFEEQLLNN NIRYNIVGGF RFYDRQEIKD
460 470 480 490 500
AIAYLRVLVN PADTVSLLRI INTPRRGIGK STIEGFVNAS KELDIPLWEI
510 520 530 540 550
ITDETSVNTL AGRSGKKTLQ FARMLQEIQS QIGELSASEA LSLVLEKSNY
560 570 580 590 600
VDDLKQKGTE EADNRLANLG ELDNAVRQFE AESEDPSLVD FLASASLTSD
610 620 630 640 650
LDDLEESGDE VSLMTLHSAK GLEFPVVFLV GLEQGTCPHA RSLNDPLDLE
660 670 680 690 700
EERRLCYVGI TRAQENLFLT HARMRYIWGS LETKIPSQFL QELPPDLLAD
710 720 730 740 750
GSTGRRTGRN APAADPKGPS IAQKQARKKT GSQSTQPAKD LIWNVGDRVM
760 770 780 790
HNNFGEGTVT HILGKGHKAN LAIKFPGIGV KIIDPSFAPL RRL
Length:793
Mass (Da):90,395
Last modified:February 1, 1997 - v1
Checksum:iE537154A73EA624B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA17505.1.
PIRiS77402.
RefSeqiNP_440825.1. NC_000911.1.
YP_005650884.1. NC_017277.1.
YP_007450708.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA17505; BAA17505; BAA17505.
GeneIDi954128.
KEGGisyn:sll1143.
PATRICi23838888. VBISynSp132158_1009.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA17505.1.
PIRiS77402.
RefSeqiNP_440825.1. NC_000911.1.
YP_005650884.1. NC_017277.1.
YP_007450708.1. NC_020286.1.

3D structure databases

ProteinModelPortaliP73465.
SMRiP73465. Positions 608-702.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP73465. 21 interactions.
STRINGi1148.sll1143.

Proteomic databases

PaxDbiP73465.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA17505; BAA17505; BAA17505.
GeneIDi954128.
KEGGisyn:sll1143.
PATRICi23838888. VBISynSp132158_1009.

Phylogenomic databases

eggNOGiCOG0210.
HOGENOMiHOG000033016.
InParanoidiP73465.
KOiK03657.
OMAiVLMQNRI.
PhylomeDBiP73465.

Family and domain databases

Gene3Di1.10.10.160. 1 hit.
3.40.50.300. 4 hits.
InterProiIPR005751. ATP-dep_DNA_helicase_PcrA.
IPR013986. DExx_box_DNA_helicase_dom.
IPR014017. DNA_helicase_UvrD-like_C.
IPR000212. DNA_helicase_UvrD/REP.
IPR027417. P-loop_NTPase.
IPR014016. UvrD-like_ATP-bd.
[Graphical view]
PANTHERiPTHR11070. PTHR11070. 1 hit.
PfamiPF00580. UvrD-helicase. 1 hit.
PF13361. UvrD_C. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR01073. pcrA. 1 hit.
PROSITEiPS51198. UVRD_HELICASE_ATP_BIND. 1 hit.
PS51217. UVRD_HELICASE_CTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / KazusaImported.

Entry informationi

Entry nameiP73465_SYNY3
AccessioniPrimary (citable) accession number: P73465
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: February 4, 2015
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.