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P73460

- RSMH_SYNY3

UniProt

P73460 - RSMH_SYNY3

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Protein
Ribosomal RNA small subunit methyltransferase H
Gene
rsmH, mraW, sll1144
Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(1402) in 16S rRNA = S-adenosyl-L-homocysteine + N(4)-methylcytosine(1402) in 16S rRNA.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei68 – 681S-adenosyl-L-methionine By similarity
Binding sitei100 – 1001S-adenosyl-L-methionine; via amide nitrogen By similarity
Binding sitei116 – 1161S-adenosyl-L-methionine By similarity
Binding sitei123 – 1231S-adenosyl-L-methionine By similarity

GO - Molecular functioni

  1. rRNA (cytosine-N4-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. rRNA base methylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA small subunit methyltransferase H (EC:2.1.1.199)
Alternative name(s):
16S rRNA m(4)C1402 methyltransferase
rRNA (cytosine-N(4)-)-methyltransferase RsmH
Gene namesi
Name:rsmH
Synonyms:mraW
Ordered Locus Names:sll1144
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 305305Ribosomal RNA small subunit methyltransferase HUniRule annotation
PRO_0000108731Add
BLAST

Proteomic databases

PaxDbiP73460.

Interactioni

Protein-protein interaction databases

STRINGi1148.sll1144.

Structurei

3D structure databases

ProteinModelPortaliP73460.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni49 – 513S-adenosyl-L-methionine binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0275.
KOiK03438.
OMAiINTYDEA.
PhylomeDBiP73460.

Family and domain databases

Gene3Di1.10.150.170. 1 hit.
3.40.50.150. 2 hits.
HAMAPiMF_01007. 16SrRNA_methyltr_H.
InterProiIPR002903. RsmH.
IPR023397. SAM-dep_MeTrfase_MraW_recog.
IPR029063. SAM-dependent_MTases-like.
[Graphical view]
PANTHERiPTHR11265. PTHR11265. 1 hit.
PfamiPF01795. Methyltransf_5. 1 hit.
[Graphical view]
PIRSFiPIRSF004486. MraW. 1 hit.
SUPFAMiSSF53335. SSF53335. 2 hits.
SSF81799. SSF81799. 1 hit.
TIGRFAMsiTIGR00006. TIGR00006. 1 hit.

Sequencei

Sequence statusi: Complete.

P73460-1 [UniParc]FASTAAdd to Basket

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MGAKSMEGMN LKQTAIADFH HVSVLPTALV EGLEPKPGGY YLDATVGAGG    50
HSERLLKLGI PLALTMIDRD VQAIAAAMER LQPLVADRKD ISINTWQGNF 100
ADFPGQLEQF DGIIADLGVS SPQLDQGDRG FSFRHTAPLD MRMDQSQDLT 150
AAEIINHWSE KDLARIFYEY GEERLSRRIA RQIVEQRPFQ TTTDLAEAIT 200
KWVPGKYRHG RIHPATRTFQ GLRIAVNDEL GSLEKFIAQA PHWLKSGGKF 250
GIISFHSLED RIVKHRFRET ENLRVLTKKP IIAGEEEQRQ NPRARSAKLR 300
WAEKI 305
Length:305
Mass (Da):34,386
Last modified:February 1, 1997 - v1
Checksum:i758F9F567247129F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000022 Genomic DNA. Translation: BAA17500.1.
PIRiS77397.
RefSeqiYP_007450703.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA17500; BAA17500; BAA17500.
KEGGisyz:MYO_19330.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000022 Genomic DNA. Translation: BAA17500.1 .
PIRi S77397.
RefSeqi YP_007450703.1. NC_020286.1.

3D structure databases

ProteinModelPortali P73460.
ModBasei Search...

Protein-protein interaction databases

STRINGi 1148.sll1144.

Proteomic databases

PaxDbi P73460.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA17500 ; BAA17500 ; BAA17500 .
KEGGi syz:MYO_19330.

Phylogenomic databases

eggNOGi COG0275.
KOi K03438.
OMAi INTYDEA.
PhylomeDBi P73460.

Family and domain databases

Gene3Di 1.10.150.170. 1 hit.
3.40.50.150. 2 hits.
HAMAPi MF_01007. 16SrRNA_methyltr_H.
InterProi IPR002903. RsmH.
IPR023397. SAM-dep_MeTrfase_MraW_recog.
IPR029063. SAM-dependent_MTases-like.
[Graphical view ]
PANTHERi PTHR11265. PTHR11265. 1 hit.
Pfami PF01795. Methyltransf_5. 1 hit.
[Graphical view ]
PIRSFi PIRSF004486. MraW. 1 hit.
SUPFAMi SSF53335. SSF53335. 2 hits.
SSF81799. SSF81799. 1 hit.
TIGRFAMsi TIGR00006. TIGR00006. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiRSMH_SYNY3
AccessioniPrimary (citable) accession number: P73460
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: February 1, 1997
Last modified: July 9, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3

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