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P73460 (RSMH_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribosomal RNA small subunit methyltransferase H

EC=2.1.1.199
Alternative name(s):
16S rRNA m(4)C1402 methyltransferase
rRNA (cytosine-N(4)-)-methyltransferase RsmH
Gene names
Name:rsmH
Synonyms:mraW
Ordered Locus Names:sll1144
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length305 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA By similarity. HAMAP-Rule MF_01007

Catalytic activity

S-adenosyl-L-methionine + cytosine(1402) in 16S rRNA = S-adenosyl-L-homocysteine + N(4)-methylcytosine(1402) in 16S rRNA. HAMAP-Rule MF_01007

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01007.

Sequence similarities

Belongs to the methyltransferase superfamily. RsmH family.

Ontologies

Keywords
   Biological processrRNA processing
   Cellular componentCytoplasm
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processrRNA base methylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionrRNA (cytosine-N4-)-methyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 305305Ribosomal RNA small subunit methyltransferase H HAMAP-Rule MF_01007
PRO_0000108731

Regions

Region49 – 513S-adenosyl-L-methionine binding By similarity

Sites

Binding site681S-adenosyl-L-methionine By similarity
Binding site1001S-adenosyl-L-methionine; via amide nitrogen By similarity
Binding site1161S-adenosyl-L-methionine By similarity
Binding site1231S-adenosyl-L-methionine By similarity

Sequences

Sequence LengthMass (Da)Tools
P73460 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 758F9F567247129F

FASTA30534,386
        10         20         30         40         50         60 
MGAKSMEGMN LKQTAIADFH HVSVLPTALV EGLEPKPGGY YLDATVGAGG HSERLLKLGI 

        70         80         90        100        110        120 
PLALTMIDRD VQAIAAAMER LQPLVADRKD ISINTWQGNF ADFPGQLEQF DGIIADLGVS 

       130        140        150        160        170        180 
SPQLDQGDRG FSFRHTAPLD MRMDQSQDLT AAEIINHWSE KDLARIFYEY GEERLSRRIA 

       190        200        210        220        230        240 
RQIVEQRPFQ TTTDLAEAIT KWVPGKYRHG RIHPATRTFQ GLRIAVNDEL GSLEKFIAQA 

       250        260        270        280        290        300 
PHWLKSGGKF GIISFHSLED RIVKHRFRET ENLRVLTKKP IIAGEEEQRQ NPRARSAKLR 


WAEKI 

« Hide

References

[1]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000022 Genomic DNA. Translation: BAA17500.1.
PIRS77397.
RefSeqYP_007450703.1. NC_020286.1.

3D structure databases

ProteinModelPortalP73460.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING1148.sll1144.

Proteomic databases

PaxDbP73460.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA17500; BAA17500; BAA17500.
GeneID14616355.
KEGGsyz:MYO_19330.

Phylogenomic databases

eggNOGCOG0275.
KOK03438.
OMAGCYLDGT.
PhylomeDBP73460.
ProtClustDBPRK00050.

Family and domain databases

Gene3D1.10.150.170. 1 hit.
HAMAPMF_01007. 16SrRNA_methyltr_H.
InterProIPR002903. RsmH.
IPR023397. SAM-dep_MeTrfase_MraW_recog.
[Graphical view]
PANTHERPTHR11265. PTHR11265. 1 hit.
PfamPF01795. Methyltransf_5. 1 hit.
[Graphical view]
PIRSFPIRSF004486. MraW. 1 hit.
SUPFAMSSF81799. SSF81799. 1 hit.
TIGRFAMsTIGR00006. TIGR00006. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRSMH_SYNY3
AccessionPrimary (citable) accession number: P73460
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: February 1, 1997
Last modified: April 16, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families