Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P73441

- DEF_SYNY3

UniProt

P73441 - DEF_SYNY3

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Peptide deformylase

Gene

def

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).By similarity

Catalytic activityi

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide.

Cofactori

Fe2+By similarityNote: Binds 1 Fe(2+) ion.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi107 – 1071IronBy similarity
Metal bindingi149 – 1491IronBy similarity
Active sitei150 – 1501By similarity
Metal bindingi153 – 1531IronBy similarity

GO - Molecular functioni

  1. iron ion binding Source: InterPro
  2. peptide deformylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide deformylase (EC:3.5.1.88)
Short name:
PDF
Alternative name(s):
Polypeptide deformylase
Gene namesi
Name:def
Ordered Locus Names:slr1549
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 187187Peptide deformylasePRO_0000082865Add
BLAST

Proteomic databases

PaxDbiP73441.

Interactioni

Protein-protein interaction databases

IntActiP73441. 2 interactions.
STRINGi1148.slr1549.

Structurei

3D structure databases

ProteinModelPortaliP73441.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the polypeptide deformylase family.Curated

Phylogenomic databases

eggNOGiCOG0242.
HOGENOMiHOG000243509.
InParanoidiP73441.
KOiK01462.
OMAiEETGEEW.
OrthoDBiEOG664CMF.
PhylomeDBiP73441.

Family and domain databases

Gene3Di3.90.45.10. 1 hit.
HAMAPiMF_00163. Pep_deformylase.
InterProiIPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view]
PANTHERiPTHR10458. PTHR10458. 1 hit.
PfamiPF01327. Pep_deformylase. 1 hit.
[Graphical view]
PIRSFiPIRSF004749. Pep_def. 1 hit.
PRINTSiPR01576. PDEFORMYLASE.
SUPFAMiSSF56420. SSF56420. 1 hit.
TIGRFAMsiTIGR00079. pept_deformyl. 1 hit.

Sequencei

Sequence statusi: Complete.

P73441-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTATILVEKQ KVDRPPLELH YLGDKVLRQP AKRIAKVDDS IRKLAKEMLQ
60 70 80 90 100
TMYSANGIGL AAPQVGINKQ LLVVDCEQDK PDEPPLIMIN PQITRTSEEL
110 120 130 140 150
CVVEEGCLSV PNVYMDVTRP RAIEVTYKDE HGRPQKRLFA ELTARVIQHE
160 170 180
MDHLNGVMFV DRVDNPLALA ESLKKEGFSM QAVKPVA
Length:187
Mass (Da):21,026
Last modified:February 1, 1997 - v1
Checksum:i0426D753D31C9891
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA17481.1.
PIRiS77378.
RefSeqiNP_440801.1. NC_000911.1.
YP_005650860.1. NC_017277.1.
YP_007450684.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA17481; BAA17481; BAA17481.
GeneIDi954104.
KEGGisyn:slr1549.
PATRICi23838834. VBISynSp132158_0982.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA17481.1 .
PIRi S77378.
RefSeqi NP_440801.1. NC_000911.1.
YP_005650860.1. NC_017277.1.
YP_007450684.1. NC_020286.1.

3D structure databases

ProteinModelPortali P73441.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P73441. 2 interactions.
STRINGi 1148.slr1549.

Proteomic databases

PaxDbi P73441.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA17481 ; BAA17481 ; BAA17481 .
GeneIDi 954104.
KEGGi syn:slr1549.
PATRICi 23838834. VBISynSp132158_0982.

Phylogenomic databases

eggNOGi COG0242.
HOGENOMi HOG000243509.
InParanoidi P73441.
KOi K01462.
OMAi EETGEEW.
OrthoDBi EOG664CMF.
PhylomeDBi P73441.

Family and domain databases

Gene3Di 3.90.45.10. 1 hit.
HAMAPi MF_00163. Pep_deformylase.
InterProi IPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view ]
PANTHERi PTHR10458. PTHR10458. 1 hit.
Pfami PF01327. Pep_deformylase. 1 hit.
[Graphical view ]
PIRSFi PIRSF004749. Pep_def. 1 hit.
PRINTSi PR01576. PDEFORMYLASE.
SUPFAMi SSF56420. SSF56420. 1 hit.
TIGRFAMsi TIGR00079. pept_deformyl. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiDEF_SYNY3
AccessioniPrimary (citable) accession number: P73441
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: November 26, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3