Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P73411

- G6PD_SYNY3

UniProt

P73411 - G6PD_SYNY3

Protein

Glucose-6-phosphate 1-dehydrogenase

Gene

zwf

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 96 (01 Oct 2014)
      Sequence version 1 (01 Feb 1997)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.UniRule annotation

    Catalytic activityi

    D-glucose 6-phosphate + NADP+ = 6-phospho-D-glucono-1,5-lactone + NADPH.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei62 – 621NADPUniRule annotation
    Binding sitei167 – 1671NADPUniRule annotation
    Binding sitei197 – 1971SubstrateUniRule annotation
    Binding sitei201 – 2011SubstrateUniRule annotation
    Binding sitei235 – 2351SubstrateUniRule annotation
    Binding sitei254 – 2541SubstrateUniRule annotation
    Active sitei259 – 2591Proton acceptorUniRule annotation
    Binding sitei359 – 3591SubstrateUniRule annotation
    Binding sitei364 – 3641SubstrateUniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate dehydrogenase activity Source: UniProtKB-HAMAP
    2. NADP binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. pentose-phosphate shunt Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Carbohydrate metabolism, Glucose metabolism

    Keywords - Ligandi

    NADP

    Enzyme and pathway databases

    UniPathwayiUPA00115; UER00408.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate 1-dehydrogenaseUniRule annotation (EC:1.1.1.49UniRule annotation)
    Short name:
    G6PDUniRule annotation
    Gene namesi
    Name:zwfUniRule annotation
    Ordered Locus Names:slr1843
    OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
    Taxonomic identifieri1111708 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
    ProteomesiUP000001425: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 509509Glucose-6-phosphate 1-dehydrogenasePRO_0000068135Add
    BLAST

    Proteomic databases

    PaxDbiP73411.
    PRIDEiP73411.

    Interactioni

    Protein-protein interaction databases

    IntActiP73411. 1 interaction.
    STRINGi1148.slr1843.

    Structurei

    3D structure databases

    ProteinModelPortaliP73411.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glucose-6-phosphate dehydrogenase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0364.
    HOGENOMiHOG000046191.
    KOiK00036.
    OMAiWRWVEPL.
    OrthoDBiEOG61308Z.
    PhylomeDBiP73411.

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    HAMAPiMF_00966. G6PD.
    InterProiIPR001282. G6P_DH.
    IPR019796. G6P_DH_AS.
    IPR022675. G6P_DH_C.
    IPR022674. G6P_DH_NAD-bd.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PANTHERiPTHR23429. PTHR23429. 1 hit.
    PfamiPF02781. G6PD_C. 1 hit.
    PF00479. G6PD_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000110. G6PD. 1 hit.
    PRINTSiPR00079. G6PDHDRGNASE.
    TIGRFAMsiTIGR00871. zwf. 1 hit.
    PROSITEiPS00069. G6P_DEHYDROGENASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P73411-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVTLLENPFR TGLRQERTPE PLILTIFGAS GDLTQRKLVP AIYQMKRERR    50
    LPPELTVVGF ARRDWSHDHF REQMRKGIEE FSTGIGSEDL WNEFAQGLFY 100
    CSGNMDDPES YLKLKNFLGE LDEKRNTRGN RVFYLAVSPN FFPPGIKQLG 150
    AAGMLSDPVK SRIVIEKPFG RDLSSAQSLN RVVQSVCKEN QVYRIDHYLG 200
    KETVQNLMVF RFANAIFEPL WNRQFVDHVQ ITVAETVGVE ERAGYYESAG 250
    ALRDMVQNHL MQLFCLTAMD PPNAIDADSI RNEKVKVLQA TRLADINNLE 300
    NAGIRGQYKA GWMGGKPVPG YREEPGVDPS STTPTFAALK LMVDNWRWQG 350
    VPFYLRTGKR MPKKVSEIAI QFRQVPLLIF QSVAHQANPN VLSLRIQPNE 400
    GISLRFEAKM PGSELRTRTV DMDFSYGSSF GVAAADAYHR LLLDCMLGDQ 450
    TLFTRADEVE EAWRVVTPVL SAWDAPSDPL SMPLYEAGTW EPAEAEWLIN 500
    KDGRRWRRL 509
    Length:509
    Mass (Da):57,886
    Last modified:February 1, 1997 - v1
    Checksum:iEC24FE8D1AFFC238
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000022 Genomic DNA. Translation: BAA17451.1.
    PIRiS77348.
    RefSeqiNP_440771.1. NC_000911.1.
    YP_005650830.1. NC_017277.1.
    YP_007450654.1. NC_020286.1.

    Genome annotation databases

    EnsemblBacteriaiBAA17451; BAA17451; BAA17451.
    GeneIDi954074.
    KEGGisyn:slr1843.
    syy:SYNGTS_0877.
    syz:MYO_18830.
    PATRICi23838768. VBISynSp132158_0950.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000022 Genomic DNA. Translation: BAA17451.1 .
    PIRi S77348.
    RefSeqi NP_440771.1. NC_000911.1.
    YP_005650830.1. NC_017277.1.
    YP_007450654.1. NC_020286.1.

    3D structure databases

    ProteinModelPortali P73411.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P73411. 1 interaction.
    STRINGi 1148.slr1843.

    Proteomic databases

    PaxDbi P73411.
    PRIDEi P73411.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAA17451 ; BAA17451 ; BAA17451 .
    GeneIDi 954074.
    KEGGi syn:slr1843.
    syy:SYNGTS_0877.
    syz:MYO_18830.
    PATRICi 23838768. VBISynSp132158_0950.

    Phylogenomic databases

    eggNOGi COG0364.
    HOGENOMi HOG000046191.
    KOi K00036.
    OMAi WRWVEPL.
    OrthoDBi EOG61308Z.
    PhylomeDBi P73411.

    Enzyme and pathway databases

    UniPathwayi UPA00115 ; UER00408 .

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    HAMAPi MF_00966. G6PD.
    InterProi IPR001282. G6P_DH.
    IPR019796. G6P_DH_AS.
    IPR022675. G6P_DH_C.
    IPR022674. G6P_DH_NAD-bd.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    PANTHERi PTHR23429. PTHR23429. 1 hit.
    Pfami PF02781. G6PD_C. 1 hit.
    PF00479. G6PD_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000110. G6PD. 1 hit.
    PRINTSi PR00079. G6PDHDRGNASE.
    TIGRFAMsi TIGR00871. zwf. 1 hit.
    PROSITEi PS00069. G6P_DEHYDROGENASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
      Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
      , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
      DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PCC 6803 / Kazusa.

    Entry informationi

    Entry nameiG6PD_SYNY3
    AccessioniPrimary (citable) accession number: P73411
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 96 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families
    3. Synechocystis PCC 6803
      Synechocystis (strain PCC 6803): entries and gene names

    External Data

    Dasty 3