ID   P73380_SYNY3            Unreviewed;       732 AA.
AC   P73380;
DT   01-FEB-1997, integrated into UniProtKB/TrEMBL.
DT   01-FEB-1997, sequence version 1.
DT   27-MAR-2024, entry version 122.
DE   SubName: Full=Slr2077 protein {ECO:0000313|EMBL:BAA17412.1};
GN   OrderedLocusNames=slr2077 {ECO:0000313|EMBL:BAA17412.1};
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Merismopediaceae;
OC   Synechocystis.
OX   NCBI_TaxID=1111708 {ECO:0000313|EMBL:BAA17412.1, ECO:0000313|Proteomes:UP000001425};
RN   [1] {ECO:0000313|EMBL:BAA17412.1, ECO:0000313|Proteomes:UP000001425}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa {ECO:0000313|Proteomes:UP000001425};
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
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DR   EMBL; BA000022; BAA17412.1; -; Genomic_DNA.
DR   PIR; S77565; S77565.
DR   AlphaFoldDB; P73380; -.
DR   SMR; P73380; -.
DR   IntAct; P73380; 8.
DR   STRING; 1148.gene:10498275; -.
DR   PaxDb; 1148-1652490; -.
DR   EnsemblBacteria; BAA17412; BAA17412; BAA17412.
DR   KEGG; syn:slr2077; -.
DR   eggNOG; COG0834; Bacteria.
DR   eggNOG; COG5001; Bacteria.
DR   InParanoid; P73380; -.
DR   PhylomeDB; P73380; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001638; Solute-binding_3/MltF_N.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   PANTHER; PTHR33121:SF85; CYCLIC DI-GMP PHOSPHODIESTERASE PDEK-RELATED; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF00497; SBP_bac_3; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00062; PBPb; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001425};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        263..284
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          335..468
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          477..732
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   732 AA;  83891 MW;  DB05712DBBF2568B CRC64;
     MNGIHRWLFR LSIIIQLLWG SAPVTGTQVV RIGVYENQPK IFLNDQNRPV GFWIDVIEAI
     AAAENWQIEY HLCEWQACLQ KLEAGKIDLM PDVAVNPERA KKFQFNQEVV LNSWSIIYAA
     NNANINSIID LEGKRIVVLK NSVQEKNLIK RLAELKIKAE IIQVDSFSEL FKKIDAGEAD
     AGAVNYFFGN RFSHQHRVRP TNMVVDTSQL FFAASRQTNP AILRNIDEQV NLLKADTDSI
     YYESQKRWLF NNPLLTIQNL RAIIHRLIII FIIVTVAIVI IWNYRLQKEI KLRKASQNQL
     SYQALHDTLT GLANRALLLQ RLEFAGHQIK NNPKSRFALL FIDLDHFKLI NDSWGHSVGD
     ALLIKIAEKL QINLRETDLA VRLGGDEFVI FLESITEIKQ AIDVAERILI HLRLPVQIQA
     KELFVKASIG IVIGSIHYYE PERLIRDADI AMYQAKNNGR NQYAVFDPSM HQTILERLSL
     EHDFRKALEQ ETLELYYQPI ISLVNDRLQG FEALIRWQHP EKGYINPEQL IAIAEETGLI
     IILGQWIMQQ ACQQIAQWRE ITNDDKIYVS INLSPNQICR PLFVEEIENI LQTTKLDGDA
     LVLEITEGVL IQHLEIVAEC LKKIKSHGIK ISIDDFGTGY SSLSYLYRLP VNYLKIDRSF
     INQITEDSPS QSIVKTIITL GDLLDIQTVA EGVETNDQLN LLKKMGCGLG QGYFWSEPMT
     VREIDCFLDC IV
//