Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P73367 (AROQ_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 96. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
3-dehydroquinate dehydratase

Short name=3-dehydroquinase
EC=4.2.1.10
Alternative name(s):
Type II DHQase
Gene names
Name:aroQ
Ordered Locus Names:sll1112
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length152 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes a trans-dehydration via an enolate intermediate By similarity. HAMAP-Rule MF_00169

Catalytic activity

3-dehydroquinate = 3-dehydroshikimate + H2O. HAMAP-Rule MF_00169

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7. HAMAP-Rule MF_00169

Subunit structure

Homododecamer By similarity. HAMAP-Rule MF_00169

Sequence similarities

Belongs to the type-II 3-dehydroquinase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 1521523-dehydroquinate dehydratase HAMAP-Rule MF_00169
PRO_0000159933

Regions

Region104 – 1052Substrate binding By similarity

Sites

Active site261Proton acceptor By similarity
Active site1031Proton donor By similarity
Binding site771Substrate By similarity
Binding site831Substrate By similarity
Binding site901Substrate By similarity
Binding site1141Substrate By similarity
Site211Transition state stabilizer By similarity

Sequences

Sequence LengthMass (Da)Tools
P73367 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 360092AEF938A2C6

FASTA15216,375
        10         20         30         40         50         60 
MTTVWKVLVL HGPNLNLLGQ REPGIYGSLT LGEIDACLRE DGVDLEAEVS TFQSNSEGQL 

        70         80         90        100        110        120 
VTAIHGALGN YHGIVFNAAA YTHTSIALRD ALAAVQLPCV EVHLSNIHKR ESFRHISHIA 

       130        140        150 
PVAIGQICGF GLNSYRLGLR ALVDYLNGQA DS 

« Hide

References

[1]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000022 Genomic DNA. Translation: BAA17398.1.
PIRS77551.
RefSeqNP_440718.1. NC_000911.1.
YP_005650777.1. NC_017277.1.
YP_007450601.1. NC_020286.1.

3D structure databases

ProteinModelPortalP73367.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP73367. 1 interaction.
STRING1148.sll1112.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA17398; BAA17398; BAA17398.
GeneID954021.
KEGGsyn:sll1112.
syy:SYNGTS_0824.
syz:MYO_18290.
PATRIC23838646. VBISynSp132158_0890.

Phylogenomic databases

eggNOGCOG0757.
HOGENOMHOG000217278.
KOK03786.
OMADFRHHSF.
OrthoDBEOG66MQVT.
PhylomeDBP73367.

Enzyme and pathway databases

UniPathwayUPA00053; UER00086.

Family and domain databases

Gene3D3.40.50.9100. 1 hit.
HAMAPMF_00169. AroQ.
InterProIPR001874. DHquinase_II.
IPR018509. DHquinase_II_CS.
[Graphical view]
PANTHERPTHR21272. PTHR21272. 1 hit.
PfamPF01220. DHquinase_II. 1 hit.
[Graphical view]
PIRSFPIRSF001399. DHquinase_II. 1 hit.
ProDomPD004527. DHquinase_II. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF52304. SSF52304. 1 hit.
TIGRFAMsTIGR01088. aroQ. 1 hit.
PROSITEPS01029. DEHYDROQUINASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROQ_SYNY3
AccessionPrimary (citable) accession number: P73367
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: February 1, 1997
Last modified: July 9, 2014
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways