Reviewed, UniProtKB/Swiss-Prot P73270 (SPEB2_SYNY3)

Names and origin

Protein names

Recommended name:
    Probable agmatinase 2
    EC=3.5.3.11
Alternative name(s):
    Agmatine ureohydrolase 2
      Short name=AUH 2

Gene names

Name:	speB2
Ordered Locus Names:	sll1077

Organism

Synechocystis sp. (strain PCC 6803) [Complete proteome] [HAMAP]

Taxonomic identifier

1148 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechocystis

Protein attributes

Sequence length	390 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Agmatine + H2O = putrescine + urea.
Cofactor	Manganese Potential.
Sequence similarities	Belongs to the arginase family. Agmatinase subfamily.

Ontologies

Keywords
Biological process	Putrescine biosynthesis
Ligand	Manganese Metal-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	putrescine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	agmatinase activity Inferred from electronic annotation. Source: EC manganese ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 390	390	Probable agmatinase 2		PRO_0000173745
Sites
	Metal binding	174	1	Manganese By similarity
	Metal binding	199	1	Manganese By similarity
	Metal binding	201	1	Manganese By similarity
	Metal binding	203	1	Manganese By similarity
	Metal binding	291	1	Manganese By similarity
	Metal binding	293	1	Manganese By similarity

Sequences

	Sequence		Length	Mass (Da)
	P73270-1 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 7612DBDD6C29A133	FASTA	390	42,964
	10 20 30 40 50 60 MSDATPFRPP SEAEEALIKE TRLPLTGWQQ EVDQGLTYGL EAAASIKDRS IPTFSRGELP 70 80 90 100 110 120 HYAGINTFMK APYLEDVREV GKYDVAIVGV PHDSGTTYRP GTRFGPQGIR RISALYTPYN 130 140 150 160 170 180 FEMGVDLREQ ISLCDVGDIF TIPANNEKSF DQISKGIAHI FSSGAFPIIL GGDHSIGFPT 190 200 210 220 230 240 VRGICRHLGD KKVGIIHFDR HVDTQETDLD ERMHTCPWFH ATNMANAPAK NLVQLGIGGW 250 260 270 280 290 300 QVPRQGVKVC RERATNILTV TDITEMSLDA AADFAIARAT DGTDCVWISF DIDCIDAGFV 310 320 330 340 350 360 PGTGWPEPGG LLPREALYLL KRIIRETNVC GMEVVEVSPP YDISDMTSLM ATRVICDTMA 370 380 390 HLVVSGQLPR TEKPAYIHAE ANMAVDEPWQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"Arginine catabolism in the cyanobacterium Synechocystis sp. strain PCC 6803 involves the urea cycle and arginase pathway." Quintero M.J., Muro-Pastor A.M., Herrero A., Flores E. J. Bacteriol. 182:1008-1015(2000) [PubMed: 10648527] [Abstract] Cited for: FUNCTION.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000022 Genomic DNA. Translation: BAA17298.1.
PIR	S77451.
RefSeq	NP_440618.1.
3D structure databases
HSSP	HSSP built from PDB template 1GQ6 based on UniProtKB P37819.
ModBase	Search...
Protein-protein interaction databases
IntAct	P73270. 1 interaction.
STRING	P73270.
Genome annotation databases
GeneID	953921.
GenomeReviews	Gene locus sll1077 in contig BA000022_GR.
KEGG	syn:sll1077.
NMPDR	fig|1148.1.peg.719.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P73270.
OMA	QGIRRIS.
Enzyme and pathway databases
BioCyc	SSP1148:SLL1077-MON.
Family and domain databases
InterPro	IPR005924. Arginase. IPR006035. Ureohydrolase. [Graphical view]
Gene3D	G3DSA:3.40.800.10. Ureohydrolase. 1 hit.
PANTHER	PTHR11358. Ureohydrolase. 1 hit.
Pfam	PF00491. Arginase. 1 hit. [Graphical view]
PRINTS	PR00116. ARGINASE.
PROSITE	PS01053. ARGINASE_1. 1 hit. PS51409. ARGINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SPEB2_SYNY3

Accession

Primary (citable) accession number: P73270

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 29, 2004
Last sequence update:	February 1, 1997
Last modified:	November 3, 2009
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)