SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P73241

- ATCS_SYNY3

UniProt

P73241 - ATCS_SYNY3

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable copper-transporting ATPase PacS

Gene
pacS, sll1920
Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at protein leveli

Functioni

May play a role in the osmotic adaptation By similarity.

Catalytic activityi

ATP + H2O = ADP + phosphate.
ATP + H2O + Cu+(Side 1) = ADP + phosphate + Cu+(Side 2).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi14 – 141 Reviewed prediction
Metal bindingi17 – 171 Reviewed prediction
Active sitei428 – 42814-aspartylphosphate intermediate Inferred
Metal bindingi633 – 6331Magnesium By similarity
Metal bindingi637 – 6371Magnesium By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. cation-transporting ATPase activity Source: InterPro
  3. copper ion binding Source: UniProtKB

GO - Biological processi

  1. copper ion import Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Copper transport, Ion transport, Transport

Keywords - Ligandi

ATP-binding, Copper, Magnesium, Metal-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable copper-transporting ATPase PacS (EC:3.6.3.54)
Gene namesi
Name:pacS
Ordered Locus Names:sll1920
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 9494Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei95 – 11521Helical; Reviewed predictionAdd
BLAST
Topological domaini116 – 12510Extracellular Reviewed prediction
Transmembranei126 – 14520Helical; Reviewed predictionAdd
BLAST
Topological domaini146 – 1527Cytoplasmic Reviewed prediction
Transmembranei153 – 17321Helical; Reviewed predictionAdd
BLAST
Topological domaini174 – 19320Extracellular Reviewed predictionAdd
BLAST
Transmembranei194 – 21421Helical; Reviewed predictionAdd
BLAST
Topological domaini215 – 342128Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei343 – 36523Helical; Reviewed predictionAdd
BLAST
Topological domaini366 – 3727Extracellular Reviewed prediction
Transmembranei373 – 39018Helical; Reviewed predictionAdd
BLAST
Topological domaini391 – 543153Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei544 – 56421Helical; Reviewed predictionAdd
BLAST
Topological domaini565 – 687123Extracellular Reviewed predictionAdd
BLAST
Transmembranei688 – 70720Helical; Reviewed predictionAdd
BLAST
Topological domaini708 – 71912Cytoplasmic Reviewed predictionAdd
BLAST
Transmembranei720 – 73819Helical; Reviewed predictionAdd
BLAST
Topological domaini739 – 7457Extracellular Reviewed prediction

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 745745Probable copper-transporting ATPase PacSPRO_0000046161Add
BLAST

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP73241.

Interactioni

Protein-protein interaction databases

IntActiP73241. 11 interactions.
MINTiMINT-223932.
STRINGi1148.sll1920.

Structurei

Secondary structure

1
745
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi3 – 119
Helixi15 – 2612
Beta strandi31 – 377
Turni38 – 414
Beta strandi42 – 476
Beta strandi49 – 513
Helixi53 – 6210
Beta strandi66 – 694

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2GCFNMR-A1-73[»]
2XMWX-ray1.80A1-71[»]
4A48X-ray1.40A/B2-70[»]
4A4JX-ray1.25A2-70[»]
ProteinModelPortaliP73241.
SMRiP73241. Positions 1-73.

Miscellaneous databases

EvolutionaryTraceiP73241.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 6966HMAAdd
BLAST

Sequence similaritiesi

Contains 1 HMA domain.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG2217.
HOGENOMiHOG000250397.
KOiK17686.
OMAiMDGVEAN.
OrthoDBiEOG6742RM.
PhylomeDBiP73241.

Family and domain databases

Gene3Di2.70.150.10. 1 hit.
3.40.1110.10. 1 hit.
3.40.50.1000. 2 hits.
InterProiIPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR027256. Cation_transp_P-typ_ATPase_IB.
IPR001757. Cation_transp_P_typ_ATPase.
IPR023214. HAD-like_dom.
IPR017969. Heavy-metal-associated_CS.
IPR006121. HeavyMe-assoc_HMA.
[Graphical view]
PfamiPF00122. E1-E2_ATPase. 1 hit.
PF00403. HMA. 1 hit.
PF00702. Hydrolase. 1 hit.
[Graphical view]
PRINTSiPR00119. CATATPASE.
SUPFAMiSSF55008. SSF55008. 1 hit.
SSF56784. SSF56784. 2 hits.
TIGRFAMsiTIGR01525. ATPase-IB_hvy. 1 hit.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
PS01047. HMA_1. 1 hit.
PS50846. HMA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P73241-1 [UniParc]FASTAAdd to Basket

« Hide

MAQTINLQLE GMRCAACASS IERAIAKVPG VQSCQVNFAL EQAVVSYHGE    50
TTPQILTDAV ERAGYHARVL KQQVLSSQQT EDRKPVFSAK LVTGLVISAV 100
LFFGSLPMML GVNIPHFPHI FHDPWLQWLL ATPVQFWSGA EFYRGAWKSV 150
RTRSATMDTL VALGTSAAYF YSVAITLFPQ WLTSQGLAAH VYFEAAAVVI 200
TLILLGRSLE QRARRETSAA IRKLMGLQPQ TALVKRGEHW ETVAIAELAI 250
NDVVRVRPGE KIPVDGVVVA GNSTVDESLV TGESFPVDKT VGTEVIGATL 300
NKSGSLDIQV SKLGQDSVLA QIIQLVQQAQ ASKAPIQHFV DRITHWFVPT 350
VIVVAIAAFC IWWLTTGNIT LAVLTLVEVL IIACPCALGL ATPTSVMVGT 400
GKGAEYGVLI KEASSLEMAE KLTAIVLDKT GTLTQGKPSV TNFFTLSPTS 450
TEESLQLIQW AASVEQYSEH PLAEAVVNYG QSQQVSLLEI DNFQAIAGCG 500
VAGQWQGQWI RLGTSNWLTD LGVTGTEHQP WQSQAQQWEK EQKTVIWLAV 550
DTEVKALLAI ADAIKPSSPQ VVQALKKLGL SVYMLTGDNQ ATAQAIADTV 600
GIRHVLAQVR PGDKAQQVEQ LQQKGNIVAM VGDGINDAPA LAQADVGIAI 650
GTGTDVAIAA SDITLIAGDL QGILTAIKLS RATMGNIRQN LFFAFIYNVI 700
GIPVAAGLFY PLFGLLLNPI LAGAAMAFSS VSVVTNALRL KKFCP 745
Length:745
Mass (Da):79,950
Last modified:February 1, 1997 - v1
Checksum:i40831F66621735FB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000022 Genomic DNA. Translation: BAA17268.1.
PIRiS75354.
RefSeqiNP_440588.1. NC_000911.1.
YP_005650646.1. NC_017277.1.
YP_007450471.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA17268; BAA17268; BAA17268.
GeneIDi953891.
KEGGisyn:sll1920.
syy:SYNGTS_0693.
syz:MYO_16990.
PATRICi23838366. VBISynSp132158_0750.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000022 Genomic DNA. Translation: BAA17268.1 .
PIRi S75354.
RefSeqi NP_440588.1. NC_000911.1.
YP_005650646.1. NC_017277.1.
YP_007450471.1. NC_020286.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2GCF NMR - A 1-73 [» ]
2XMW X-ray 1.80 A 1-71 [» ]
4A48 X-ray 1.40 A/B 2-70 [» ]
4A4J X-ray 1.25 A 2-70 [» ]
ProteinModelPortali P73241.
SMRi P73241. Positions 1-73.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P73241. 11 interactions.
MINTi MINT-223932.
STRINGi 1148.sll1920.

Proteomic databases

PaxDbi P73241.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA17268 ; BAA17268 ; BAA17268 .
GeneIDi 953891.
KEGGi syn:sll1920.
syy:SYNGTS_0693.
syz:MYO_16990.
PATRICi 23838366. VBISynSp132158_0750.

Phylogenomic databases

eggNOGi COG2217.
HOGENOMi HOG000250397.
KOi K17686.
OMAi MDGVEAN.
OrthoDBi EOG6742RM.
PhylomeDBi P73241.

Miscellaneous databases

EvolutionaryTracei P73241.

Family and domain databases

Gene3Di 2.70.150.10. 1 hit.
3.40.1110.10. 1 hit.
3.40.50.1000. 2 hits.
InterProi IPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR027256. Cation_transp_P-typ_ATPase_IB.
IPR001757. Cation_transp_P_typ_ATPase.
IPR023214. HAD-like_dom.
IPR017969. Heavy-metal-associated_CS.
IPR006121. HeavyMe-assoc_HMA.
[Graphical view ]
Pfami PF00122. E1-E2_ATPase. 1 hit.
PF00403. HMA. 1 hit.
PF00702. Hydrolase. 1 hit.
[Graphical view ]
PRINTSi PR00119. CATATPASE.
SUPFAMi SSF55008. SSF55008. 1 hit.
SSF56784. SSF56784. 2 hits.
TIGRFAMsi TIGR01525. ATPase-IB_hvy. 1 hit.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEi PS00154. ATPASE_E1_E2. 1 hit.
PS01047. HMA_1. 1 hit.
PS50846. HMA_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiATCS_SYNY3
AccessioniPrimary (citable) accession number: P73241
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: September 3, 2014
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3

Similar proteinsi