ID   FABI_SYNY3              Reviewed;         258 AA.
AC   P73016;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2000, sequence version 2.
DT   16-JUN-2009, entry version 58.
DE   RecName: Full=Enoyl-[acyl-carrier-protein] reductase [NADH];
DE            EC=1.3.1.9;
DE   AltName: Full=NADH-dependent enoyl-ACP reductase;
GN   Name=fabI; Synonyms=envM; OrderedLocusNames=slr1051;
OS   Synechocystis sp. (strain PCC 6803).
OC   Bacteria; Cyanobacteria; Chroococcales; Synechocystis.
OX   NCBI_TaxID=1148;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   MEDLINE=97061201; PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T.,
RA   Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S.,
RA   Shimpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M.,
RA   Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the
RT   entire genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
CC   -!- CATALYTIC ACTIVITY: Acyl-[acyl-carrier-protein] + NAD(+) = trans-
CC       2,3-dehydroacyl-[acyl-carrier-protein] + NADH.
CC   -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases
CC       (SDR) family. FabI subfamily.
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DR   EMBL; BA000022; BAA17036.1; ALT_INIT; Genomic_DNA.
DR   PIR; S74996; S74996.
DR   RefSeq; NP_440356.1; -.
DR   HSSP; P29132; 1DFI.
DR   GeneID; 953656; -.
DR   GenomeReviews; BA000022_GR; slr1051.
DR   KEGG; syn:slr1051; -.
DR   NMPDR; fig|1148.1.peg.457; -.
DR   HOGENOM; P73016; -.
DR   BioCyc; SSP1148:SLR1051-MON; -.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   GO; GO:0004318; F:enoyl-[acyl-carrier-protein] reductase (NAD...; IEA:EC.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR002198; DH_sc/Rdtase_SDR.
DR   InterPro; IPR014358; Enoyl-ACP_Rdtase_NADH.
DR   InterPro; IPR002347; Glc/ribitol_DH.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   PANTHER; PTHR19410; ADH_short_C2; 1.
DR   PANTHER; PTHR19410:SF12; Enoyl-ACP_rdct; 1.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
PE   3: Inferred from homology;
KW   Complete proteome; Fatty acid biosynthesis; Lipid synthesis; NAD;
KW   Oxidoreductase.
FT   CHAIN         1    258       Enoyl-[acyl-carrier-protein] reductase
FT                                [NADH].
FT                                /FTId=PRO_0000054912.
FT   NP_BIND      10     36       NAD (By similarity).
FT   ACT_SITE    158    158       Proton acceptor (By similarity).
SQ   SEQUENCE   258 AA;  27626 MW;  E912F0DF124FAE49 CRC64;
     MLDLSGKHAF VTGIANNRSI AWGIAQQLHQ AGAEIGVSYL PDEKGRFEKK VRELTEPLHP
     TLVLPGDVQD DAQVDALFHS VKEKWGKLDI LIHCLAFADK SGLTGNYTDI PKEAFSQAME
     ISTYSLGRLA RGAKPLMTNG GSIITLTYFG GVKVIPNYNL MGVAKAGLEM TVRYLAAELG
     PQNIRVNGIS AGPIRTLASS AVGGILDMIH HVEEVAPLKR TVTQTEVGNT AAFLASDLSS
     GITGQIIYVD SGYEIMGM
//