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Protein

Uncharacterized RNA pseudouridine synthase slr1592

Gene

slr1592

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

RNA uridine = RNA pseudouridine.

GO - Molecular functioni

  1. pseudouridine synthase activity Source: InterPro
  2. RNA binding Source: InterPro

GO - Biological processi

  1. pseudouridine synthesis Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized RNA pseudouridine synthase slr1592 (EC:5.4.99.-)
Alternative name(s):
RNA pseudouridylate synthase
RNA-uridine isomerase
Gene namesi
Ordered Locus Names:slr1592
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 291291Uncharacterized RNA pseudouridine synthase slr1592PRO_0000162746Add
BLAST

Interactioni

Protein-protein interaction databases

IntActiP72970. 2 interactions.
STRINGi1148.slr1592.

Structurei

3D structure databases

ProteinModelPortaliP72970.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase RluA family.Curated

Phylogenomic databases

eggNOGiCOG0564.
InParanoidiP72970.
KOiK06180.
OMAiFTGRPHQ.
OrthoDBiEOG6P070X.
PhylomeDBiP72970.

Family and domain databases

InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR006225. PsdUridine_synth_RluC/D.
IPR006224. PsdUridine_synth_RluC/D_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
IPR002942. S4_RNA-bd.
[Graphical view]
PfamiPF00849. PseudoU_synth_2. 1 hit.
[Graphical view]
SMARTiSM00363. S4. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00005. rluA_subfam. 1 hit.
PROSITEiPS01129. PSI_RLU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P72970-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLDFYSQRYL HSERQAWQER IEQGQIEVDG KTVDPTYPLQ AGQTLTYWRS
60 70 80 90 100
PWVEPEVPLQ LSVLHRDEDL WAIDKPSGLP VLPGGDFVYH TVLEQLKIQY
110 120 130 140 150
PQESLFPLHR LGTGTSGLLL LGRSTLGRRE LSRQFREHIC RKIYRTVIGP
160 170 180 190 200
CDLPEKFECH QAIGKIPYPQ LGYIYAASSH GKPAQSYGRI LARSPEKTWL
210 220 230 240 250
EVEIRTGRPH QIRIHLASLG YPLLGDRLYG PGGVPINCRT ARPSDGGYTL
260 270 280 290
HSYQLGFLHL HTQQAIKLTA PLPPELITPE VKTIALETEK H
Length:291
Mass (Da):33,096
Last modified:February 1, 1997 - v1
Checksum:iD93D79A569920AE8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA16988.1.
PIRiS74948.
RefSeqiNP_440308.1. NC_000911.1.
YP_005650365.1. NC_017277.1.
YP_007450191.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA16988; BAA16988; BAA16988.
GeneIDi953607.
KEGGisyn:slr1592.
PATRICi23837754. VBISynSp132158_0446.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA16988.1.
PIRiS74948.
RefSeqiNP_440308.1. NC_000911.1.
YP_005650365.1. NC_017277.1.
YP_007450191.1. NC_020286.1.

3D structure databases

ProteinModelPortaliP72970.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP72970. 2 interactions.
STRINGi1148.slr1592.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA16988; BAA16988; BAA16988.
GeneIDi953607.
KEGGisyn:slr1592.
PATRICi23837754. VBISynSp132158_0446.

Phylogenomic databases

eggNOGiCOG0564.
InParanoidiP72970.
KOiK06180.
OMAiFTGRPHQ.
OrthoDBiEOG6P070X.
PhylomeDBiP72970.

Family and domain databases

InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR006225. PsdUridine_synth_RluC/D.
IPR006224. PsdUridine_synth_RluC/D_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
IPR002942. S4_RNA-bd.
[Graphical view]
PfamiPF00849. PseudoU_synth_2. 1 hit.
[Graphical view]
SMARTiSM00363. S4. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00005. rluA_subfam. 1 hit.
PROSITEiPS01129. PSI_RLU. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiY1592_SYNY3
AccessioniPrimary (citable) accession number: P72970
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: February 1, 1997
Last modified: January 7, 2015
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.