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Protein

Urease accessory protein UreG

Gene

ureG

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi12 – 19GTPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processNickel insertion
LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Urease accessory protein UreGUniRule annotation
Gene namesi
Name:ureGUniRule annotation
Ordered Locus Names:sll0643
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesMerismopediaceaeSynechocystis
Proteomesi
  • UP000001425 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000676741 – 206Urease accessory protein UreGAdd BLAST206

Proteomic databases

PaxDbiP72955
PRIDEiP72955

Interactioni

Subunit structurei

Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.UniRule annotation

Protein-protein interaction databases

STRINGi1148.SYNGTS_0397

Structurei

3D structure databases

ProteinModelPortaliP72955
SMRiP72955
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000236979
InParanoidiP72955
KOiK03189
OMAiAIREDCS
PhylomeDBiP72955

Family and domain databases

HAMAPiMF_01389 UreG, 1 hit
InterProiView protein in InterPro
IPR003495 CobW/HypB/UreG_dom
IPR012202 NiFe-hyd/urease_mat_GTPase
IPR027417 P-loop_NTPase
IPR004400 UreG
PANTHERiPTHR31715 PTHR31715, 1 hit
PfamiView protein in Pfam
PF02492 cobW, 1 hit
PIRSFiPIRSF005624 Ni-bind_GTPase, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00101 ureG, 1 hit

Sequencei

Sequence statusi: Complete.

P72955-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQTPLRIGI AGPVGSGKTA LLEALCKALR QKYQLAVVTN DIYTQEDAQF
60 70 80 90 100
LVRAEALTPD RILGVETGGC PHTAIREDAS LNLAAIADLE ARFMPLDMVF
110 120 130 140 150
LESGGDNLAA TFSPELVDLT LYVIDVAAGD KIPRKGGPGI TKSDLLVINK
160 170 180 190 200
IDLAPMVGAD LGIMDRDAKK MRGEKPFVFT NLKTATGLST VVDFVEHYLP

TKVLAS
Length:206
Mass (Da):22,013
Last modified:February 1, 1997 - v1
Checksum:i8A45AD507F49B1B1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA Translation: BAA16973.1
PIRiS74933

Genome annotation databases

EnsemblBacteriaiBAA16973; BAA16973; BAA16973
KEGGisyn:sll0643

Similar proteinsi

Entry informationi

Entry nameiUREG_SYNY3
AccessioniPrimary (citable) accession number: P72955
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: May 23, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health