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P72955 (UREG_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 86. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Urease accessory protein UreG
Gene names
Name:ureG
Ordered Locus Names:sll0643
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length206 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG By similarity. HAMAP-Rule MF_01389

Subunit structure

Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01389.

Sequence similarities

Belongs to the UreG family.

Ontologies

Keywords
   Biological processNickel insertion
   Cellular componentCytoplasm
   LigandGTP-binding
Nucleotide-binding
   Molecular functionChaperone
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: InterPro

GTP binding

Inferred from electronic annotation. Source: UniProtKB-KW

GTPase activity

Inferred from electronic annotation. Source: InterPro

metallochaperone activity

Inferred from electronic annotation. Source: InterPro

nickel cation binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 206206Urease accessory protein UreG HAMAP-Rule MF_01389
PRO_0000067674

Regions

Nucleotide binding12 – 198GTP By similarity

Sequences

Sequence LengthMass (Da)Tools
P72955 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 8A45AD507F49B1B1

FASTA20622,013
        10         20         30         40         50         60 
MAQTPLRIGI AGPVGSGKTA LLEALCKALR QKYQLAVVTN DIYTQEDAQF LVRAEALTPD 

        70         80         90        100        110        120 
RILGVETGGC PHTAIREDAS LNLAAIADLE ARFMPLDMVF LESGGDNLAA TFSPELVDLT 

       130        140        150        160        170        180 
LYVIDVAAGD KIPRKGGPGI TKSDLLVINK IDLAPMVGAD LGIMDRDAKK MRGEKPFVFT 

       190        200 
NLKTATGLST VVDFVEHYLP TKVLAS 

« Hide

References

[1]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000022 Genomic DNA. Translation: BAA16973.1.
PIRS74933.
RefSeqNP_440293.1. NC_000911.1.
YP_005650350.1. NC_017277.1.
YP_007450176.1. NC_020286.1.

3D structure databases

ProteinModelPortalP72955.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING1148.sll0643.

Proteomic databases

PaxDbP72955.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA16973; BAA16973; BAA16973.
GeneID953592.
KEGGsyn:sll0643.
syy:SYNGTS_0397.
syz:MYO_14010.
PATRIC23837720. VBISynSp132158_0430.

Phylogenomic databases

eggNOGCOG0378.
HOGENOMHOG000236979.
KOK03189.
OMADRDATRM.
OrthoDBEOG6RC3T9.
PhylomeDBP72955.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_01389. UreG.
InterProIPR003593. AAA+_ATPase.
IPR003495. CobW/HypB/UreG_dom.
IPR012202. NiFe-hyd/urease_mat_GTPase.
IPR027417. P-loop_NTPase.
IPR004400. Urease_accessory_UreG.
[Graphical view]
PfamPF02492. cobW. 1 hit.
[Graphical view]
PIRSFPIRSF005624. Ni-bind_GTPase. 1 hit.
SMARTSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00101. ureG. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUREG_SYNY3
AccessionPrimary (citable) accession number: P72955
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: July 9, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families