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P72955

- UREG_SYNY3

UniProt

P72955 - UREG_SYNY3

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Protein

Urease accessory protein UreG

Gene

ureG

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi12 – 198GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-KW
  3. nickel cation binding Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Nickel insertion

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Urease accessory protein UreGUniRule annotation
Gene namesi
Name:ureGUniRule annotation
Ordered Locus Names:sll0643
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 206206Urease accessory protein UreGPRO_0000067674Add
BLAST

Proteomic databases

PaxDbiP72955.

Interactioni

Subunit structurei

Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.UniRule annotation

Protein-protein interaction databases

STRINGi1148.sll0643.

Structurei

3D structure databases

ProteinModelPortaliP72955.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UreG family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0378.
HOGENOMiHOG000236979.
InParanoidiP72955.
KOiK03189.
OMAiDRDATRM.
OrthoDBiEOG6RC3T9.
PhylomeDBiP72955.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_01389. UreG.
InterProiIPR003593. AAA+_ATPase.
IPR003495. CobW/HypB/UreG_dom.
IPR012202. NiFe-hyd/urease_mat_GTPase.
IPR027417. P-loop_NTPase.
IPR004400. UreG.
[Graphical view]
PfamiPF02492. cobW. 1 hit.
[Graphical view]
PIRSFiPIRSF005624. Ni-bind_GTPase. 1 hit.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00101. ureG. 1 hit.

Sequencei

Sequence statusi: Complete.

P72955-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAQTPLRIGI AGPVGSGKTA LLEALCKALR QKYQLAVVTN DIYTQEDAQF
60 70 80 90 100
LVRAEALTPD RILGVETGGC PHTAIREDAS LNLAAIADLE ARFMPLDMVF
110 120 130 140 150
LESGGDNLAA TFSPELVDLT LYVIDVAAGD KIPRKGGPGI TKSDLLVINK
160 170 180 190 200
IDLAPMVGAD LGIMDRDAKK MRGEKPFVFT NLKTATGLST VVDFVEHYLP

TKVLAS
Length:206
Mass (Da):22,013
Last modified:February 1, 1997 - v1
Checksum:i8A45AD507F49B1B1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA16973.1.
PIRiS74933.
RefSeqiNP_440293.1. NC_000911.1.
YP_005650350.1. NC_017277.1.
YP_007450176.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA16973; BAA16973; BAA16973.
GeneIDi953592.
KEGGisyn:sll0643.
PATRICi23837720. VBISynSp132158_0430.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA16973.1 .
PIRi S74933.
RefSeqi NP_440293.1. NC_000911.1.
YP_005650350.1. NC_017277.1.
YP_007450176.1. NC_020286.1.

3D structure databases

ProteinModelPortali P72955.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 1148.sll0643.

Proteomic databases

PaxDbi P72955.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA16973 ; BAA16973 ; BAA16973 .
GeneIDi 953592.
KEGGi syn:sll0643.
PATRICi 23837720. VBISynSp132158_0430.

Phylogenomic databases

eggNOGi COG0378.
HOGENOMi HOG000236979.
InParanoidi P72955.
KOi K03189.
OMAi DRDATRM.
OrthoDBi EOG6RC3T9.
PhylomeDBi P72955.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_01389. UreG.
InterProi IPR003593. AAA+_ATPase.
IPR003495. CobW/HypB/UreG_dom.
IPR012202. NiFe-hyd/urease_mat_GTPase.
IPR027417. P-loop_NTPase.
IPR004400. UreG.
[Graphical view ]
Pfami PF02492. cobW. 1 hit.
[Graphical view ]
PIRSFi PIRSF005624. Ni-bind_GTPase. 1 hit.
SMARTi SM00382. AAA. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00101. ureG. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiUREG_SYNY3
AccessioniPrimary (citable) accession number: P72955
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: November 26, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3