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Protein

Urease accessory protein UreG

Gene

ureG

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi12 – 198GTPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Nickel insertion

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Urease accessory protein UreGUniRule annotation
Gene namesi
Name:ureGUniRule annotation
Ordered Locus Names:sll0643
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 206206Urease accessory protein UreGPRO_0000067674Add
BLAST

Proteomic databases

PaxDbiP72955.

Interactioni

Subunit structurei

Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliP72955.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UreG family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0378.
HOGENOMiHOG000236979.
InParanoidiP72955.
KOiK03189.
OMAiREDCSIN.
OrthoDBiEOG6RC3T9.
PhylomeDBiP72955.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_01389. UreG.
InterProiIPR003593. AAA+_ATPase.
IPR003495. CobW/HypB/UreG_dom.
IPR027417. P-loop_NTPase.
IPR004400. UreG.
[Graphical view]
PANTHERiPTHR31715. PTHR31715. 1 hit.
PfamiPF02492. cobW. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00101. ureG. 1 hit.

Sequencei

Sequence statusi: Complete.

P72955-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQTPLRIGI AGPVGSGKTA LLEALCKALR QKYQLAVVTN DIYTQEDAQF
60 70 80 90 100
LVRAEALTPD RILGVETGGC PHTAIREDAS LNLAAIADLE ARFMPLDMVF
110 120 130 140 150
LESGGDNLAA TFSPELVDLT LYVIDVAAGD KIPRKGGPGI TKSDLLVINK
160 170 180 190 200
IDLAPMVGAD LGIMDRDAKK MRGEKPFVFT NLKTATGLST VVDFVEHYLP

TKVLAS
Length:206
Mass (Da):22,013
Last modified:February 1, 1997 - v1
Checksum:i8A45AD507F49B1B1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA16973.1.
PIRiS74933.

Genome annotation databases

EnsemblBacteriaiBAA16973; BAA16973; BAA16973.
KEGGisyy:SYNGTS_0397.
syz:MYO_14010.
PATRICi23837720. VBISynSp132158_0430.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA16973.1.
PIRiS74933.

3D structure databases

ProteinModelPortaliP72955.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiP72955.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA16973; BAA16973; BAA16973.
KEGGisyy:SYNGTS_0397.
syz:MYO_14010.
PATRICi23837720. VBISynSp132158_0430.

Phylogenomic databases

eggNOGiCOG0378.
HOGENOMiHOG000236979.
InParanoidiP72955.
KOiK03189.
OMAiREDCSIN.
OrthoDBiEOG6RC3T9.
PhylomeDBiP72955.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_01389. UreG.
InterProiIPR003593. AAA+_ATPase.
IPR003495. CobW/HypB/UreG_dom.
IPR027417. P-loop_NTPase.
IPR004400. UreG.
[Graphical view]
PANTHERiPTHR31715. PTHR31715. 1 hit.
PfamiPF02492. cobW. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00101. ureG. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiUREG_SYNY3
AccessioniPrimary (citable) accession number: P72955
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: July 22, 2015
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.