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P72872

- DUS2_SYNY3

UniProt

P72872 - DUS2_SYNY3

Protein

Probable tRNA-dihydrouridine synthase 2

Gene

dus2

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 84 (01 Oct 2014)
      Sequence version 1 (01 Feb 1997)
      Previous versions | rss
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    Functioni

    Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.By similarity

    Cofactori

    FAD.By similarity

    GO - Molecular functioni

    1. flavin adenine dinucleotide binding Source: InterPro
    2. tRNA dihydrouridine synthase activity Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    tRNA processing

    Keywords - Ligandi

    FAD, Flavoprotein

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable tRNA-dihydrouridine synthase 2 (EC:1.-.-.-)
    Gene namesi
    Name:dus2
    Ordered Locus Names:sll0926
    OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
    Taxonomic identifieri1111708 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
    ProteomesiUP000001425: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 334334Probable tRNA-dihydrouridine synthase 2PRO_0000162151Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    IntActiP72872. 1 interaction.
    STRINGi1148.sll0926.

    Structurei

    3D structure databases

    ProteinModelPortaliP72872.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the Dus family.Curated

    Phylogenomic databases

    eggNOGiCOG0042.
    HOGENOMiHOG000259834.
    KOiK05539.
    OMAiHMLGLRH.
    OrthoDBiEOG6C8MTR.
    PhylomeDBiP72872.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    InterProiIPR013785. Aldolase_TIM.
    IPR004653. tRNA_dU_YjbN.
    IPR001269. tRNA_hU_synthase.
    IPR018517. tRNA_hU_synthase_CS.
    [Graphical view]
    PANTHERiPTHR11082. PTHR11082. 1 hit.
    PfamiPF01207. Dus. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006621. Dus. 1 hit.
    TIGRFAMsiTIGR00742. yjbN. 1 hit.
    PROSITEiPS01136. UPF0034. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P72872-1 [UniParc]FASTAAdd to Basket

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    MTKIFADSSI NPLSVAPMMD HTDRHFRYFL RQLTRHTLLY TEMITAQAIL    50
    HGDRQRLLNF SPEEKPVALQ LGGDDPQLLA ECARIGQDWG YDEINLNVGC 100
    PSDRVQSGNF GACLMAQPDL VAQCVSAMQK AVEIPVTVKH RIGIDHRDSY 150
    EDLVHFVEIV ANAGCQRFTV HARKAWLQGL SPKENRTIPP LRYEDVYQLK 200
    KDFPQLLIEI NGGITQTEQI QQHLSHVDAV MVGRAAYENP YLFATVDRDI 250
    YHKTNLVPSR AEIIERMLPY VEERLRHGDR LNQITRHLLS LFNGQPRAKF 300
    WRRTLSDSTL LASAGPELLQ TALQAQKFPG VLVA 334
    Length:334
    Mass (Da):37,929
    Last modified:February 1, 1997 - v1
    Checksum:iE5AB3C5E98268719
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000022 Genomic DNA. Translation: BAA16888.1.
    PIRiS74737.
    RefSeqiNP_440208.1. NC_000911.1.
    YP_005650265.1. NC_017277.1.
    YP_007450091.1. NC_020286.1.

    Genome annotation databases

    EnsemblBacteriaiBAA16888; BAA16888; BAA16888.
    GeneIDi953507.
    KEGGisyn:sll0926.
    syy:SYNGTS_0312.
    syz:MYO_13150.
    PATRICi23837546. VBISynSp132158_0344.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000022 Genomic DNA. Translation: BAA16888.1 .
    PIRi S74737.
    RefSeqi NP_440208.1. NC_000911.1.
    YP_005650265.1. NC_017277.1.
    YP_007450091.1. NC_020286.1.

    3D structure databases

    ProteinModelPortali P72872.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P72872. 1 interaction.
    STRINGi 1148.sll0926.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAA16888 ; BAA16888 ; BAA16888 .
    GeneIDi 953507.
    KEGGi syn:sll0926.
    syy:SYNGTS_0312.
    syz:MYO_13150.
    PATRICi 23837546. VBISynSp132158_0344.

    Phylogenomic databases

    eggNOGi COG0042.
    HOGENOMi HOG000259834.
    KOi K05539.
    OMAi HMLGLRH.
    OrthoDBi EOG6C8MTR.
    PhylomeDBi P72872.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    InterProi IPR013785. Aldolase_TIM.
    IPR004653. tRNA_dU_YjbN.
    IPR001269. tRNA_hU_synthase.
    IPR018517. tRNA_hU_synthase_CS.
    [Graphical view ]
    PANTHERi PTHR11082. PTHR11082. 1 hit.
    Pfami PF01207. Dus. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006621. Dus. 1 hit.
    TIGRFAMsi TIGR00742. yjbN. 1 hit.
    PROSITEi PS01136. UPF0034. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
      Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
      , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
      DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PCC 6803 / Kazusa.

    Entry informationi

    Entry nameiDUS2_SYNY3
    AccessioniPrimary (citable) accession number: P72872
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 84 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Synechocystis PCC 6803
      Synechocystis (strain PCC 6803): entries and gene names

    External Data

    Dasty 3