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Protein

Probable tRNA-dihydrouridine synthase 2

Gene

dus2

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.By similarity

Cofactori

FADBy similarity

GO - Molecular functioni

  1. flavin adenine dinucleotide binding Source: InterPro
  2. tRNA dihydrouridine synthase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

FAD, Flavoprotein

Names & Taxonomyi

Protein namesi
Recommended name:
Probable tRNA-dihydrouridine synthase 2 (EC:1.-.-.-)
Gene namesi
Name:dus2
Ordered Locus Names:sll0926
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 334334Probable tRNA-dihydrouridine synthase 2PRO_0000162151Add
BLAST

Interactioni

Protein-protein interaction databases

IntActiP72872. 1 interaction.
STRINGi1148.sll0926.

Structurei

3D structure databases

ProteinModelPortaliP72872.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Dus family.Curated

Phylogenomic databases

eggNOGiCOG0042.
HOGENOMiHOG000259834.
InParanoidiP72872.
KOiK05539.
OMAiDWGYDEI.
OrthoDBiEOG6C8MTR.
PhylomeDBiP72872.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR004653. tRNA_dU_YjbN.
IPR001269. tRNA_hU_synthase.
IPR018517. tRNA_hU_synthase_CS.
[Graphical view]
PANTHERiPTHR11082. PTHR11082. 1 hit.
PfamiPF01207. Dus. 1 hit.
[Graphical view]
PIRSFiPIRSF006621. Dus. 1 hit.
TIGRFAMsiTIGR00742. yjbN. 1 hit.
PROSITEiPS01136. UPF0034. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P72872-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKIFADSSI NPLSVAPMMD HTDRHFRYFL RQLTRHTLLY TEMITAQAIL
60 70 80 90 100
HGDRQRLLNF SPEEKPVALQ LGGDDPQLLA ECARIGQDWG YDEINLNVGC
110 120 130 140 150
PSDRVQSGNF GACLMAQPDL VAQCVSAMQK AVEIPVTVKH RIGIDHRDSY
160 170 180 190 200
EDLVHFVEIV ANAGCQRFTV HARKAWLQGL SPKENRTIPP LRYEDVYQLK
210 220 230 240 250
KDFPQLLIEI NGGITQTEQI QQHLSHVDAV MVGRAAYENP YLFATVDRDI
260 270 280 290 300
YHKTNLVPSR AEIIERMLPY VEERLRHGDR LNQITRHLLS LFNGQPRAKF
310 320 330
WRRTLSDSTL LASAGPELLQ TALQAQKFPG VLVA
Length:334
Mass (Da):37,929
Last modified:February 1, 1997 - v1
Checksum:iE5AB3C5E98268719
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA16888.1.
PIRiS74737.
RefSeqiNP_440208.1. NC_000911.1.
YP_005650265.1. NC_017277.1.
YP_007450091.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA16888; BAA16888; BAA16888.
KEGGisyn:sll0926.
PATRICi23837546. VBISynSp132158_0344.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA16888.1.
PIRiS74737.
RefSeqiNP_440208.1. NC_000911.1.
YP_005650265.1. NC_017277.1.
YP_007450091.1. NC_020286.1.

3D structure databases

ProteinModelPortaliP72872.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP72872. 1 interaction.
STRINGi1148.sll0926.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA16888; BAA16888; BAA16888.
KEGGisyn:sll0926.
PATRICi23837546. VBISynSp132158_0344.

Phylogenomic databases

eggNOGiCOG0042.
HOGENOMiHOG000259834.
InParanoidiP72872.
KOiK05539.
OMAiDWGYDEI.
OrthoDBiEOG6C8MTR.
PhylomeDBiP72872.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR004653. tRNA_dU_YjbN.
IPR001269. tRNA_hU_synthase.
IPR018517. tRNA_hU_synthase_CS.
[Graphical view]
PANTHERiPTHR11082. PTHR11082. 1 hit.
PfamiPF01207. Dus. 1 hit.
[Graphical view]
PIRSFiPIRSF006621. Dus. 1 hit.
TIGRFAMsiTIGR00742. yjbN. 1 hit.
PROSITEiPS01136. UPF0034. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiDUS2_SYNY3
AccessioniPrimary (citable) accession number: P72872
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: April 1, 2015
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.