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P72856 (DPO3B_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
DNA polymerase III subunit beta

EC=2.7.7.7
Gene names
Name:dnaN
Ordered Locus Names:slr0965
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length391 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA By similarity.

Catalytic activity

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

Subunit structure

DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 391391DNA polymerase III subunit beta
PRO_0000105475

Sequences

Sequence LengthMass (Da)Tools
P72856 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 5FA9942EE1C7A7E9

FASTA39142,088
        10         20         30         40         50         60 
MKLICRQSDL SSGLSLVSRA VSSRPTHPVL GNVLLEADAD KNYLRLTAFD LSLGIQSSFT 

        70         80         90        100        110        120 
ADVQQSGRIT LPAKLLNDIV SRLPDGDITL AIDPDGDAGD SHLTTITSES GRFQIRGLDA 

       130        140        150        160        170        180 
DDFPALPTVE GVKPLLLPVA TLNEGLRGAL FAASTDETKQ VLTGVHIKGS GDSLEFAATD 

       190        200        210        220        230        240 
GHRLAVVEAP TQIENDEGEA VITGSDLADF AVTIPARALR ELERMVASQG NSDLVSLVVN 

       250        260        270        280        290        300 
DTQVIFELGD QRLTSRKLEG AYPAYDQLIP RQFSRTVTME RKRLITSLER VSVLADQKNN 

       310        320        330        340        350        360 
LVTFTLQSPG NQLQLAVEAQ DLGHGEESMG AEIIGEGGQI AFNIKYLMDG LKALPSNDIQ 

       370        380        390 
MQLNEGNQPV IFTPLGGLKM TYLVMPVRLV N 

« Hide

References

[1]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000022 Genomic DNA. Translation: BAA16871.1.
PIRS74720.
RefSeqNP_440191.1. NC_000911.1.
YP_005650248.1. NC_017277.1.
YP_007450074.1. NC_020286.1.

3D structure databases

ProteinModelPortalP72856.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING1148.slr0965.

Proteomic databases

PaxDbP72856.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA16871; BAA16871; BAA16871.
GeneID12255936.
14615720.
953490.
KEGGsyn:slr0965.
syy:SYNGTS_0295.
syz:MYO_12980.
PATRIC23837508. VBISynSp132158_0325.

Phylogenomic databases

eggNOGCOG0592.
HOGENOMHOG000071791.
KOK02338.
OMADYNRVIP.
OrthoDBEOG65J53F.
PhylomeDBP72856.
ProtClustDBPRK05643.

Family and domain databases

InterProIPR001001. DNA_polIII_beta.
IPR022635. DNA_polIII_beta_C.
IPR022637. DNA_polIII_beta_cen.
IPR022634. DNA_polIII_beta_N.
[Graphical view]
PfamPF00712. DNA_pol3_beta. 1 hit.
PF02767. DNA_pol3_beta_2. 1 hit.
PF02768. DNA_pol3_beta_3. 1 hit.
[Graphical view]
PIRSFPIRSF000804. DNA_pol_III_b. 1 hit.
SMARTSM00480. POL3Bc. 1 hit.
[Graphical view]
TIGRFAMsTIGR00663. dnan. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDPO3B_SYNY3
AccessionPrimary (citable) accession number: P72856
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: April 16, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names