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P72856

- DPO3B_SYNY3

UniProt

P72856 - DPO3B_SYNY3

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Protein

DNA polymerase III subunit beta

Gene

dnaN

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP-independent) along duplex DNA (By similarity).By similarity

Catalytic activityi

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

GO - Molecular functioni

  1. 3'-5' exonuclease activity Source: InterPro
  2. DNA binding Source: InterPro
  3. DNA-directed DNA polymerase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase

Keywords - Biological processi

DNA replication

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymerase III subunit beta (EC:2.7.7.7)
Gene namesi
Name:dnaN
Ordered Locus Names:slr0965
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
  2. DNA polymerase III complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 391391DNA polymerase III subunit betaPRO_0000105475Add
BLAST

Proteomic databases

PaxDbiP72856.

Interactioni

Subunit structurei

DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex (By similarity).By similarity

Protein-protein interaction databases

STRINGi1148.slr0965.

Structurei

3D structure databases

ProteinModelPortaliP72856.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0592.
HOGENOMiHOG000071791.
InParanoidiP72856.
KOiK02338.
OMAiVCGLNGH.
OrthoDBiEOG65J53F.
PhylomeDBiP72856.

Family and domain databases

InterProiIPR001001. DNA_polIII_beta.
IPR022635. DNA_polIII_beta_C.
IPR022637. DNA_polIII_beta_cen.
IPR022634. DNA_polIII_beta_N.
[Graphical view]
PfamiPF00712. DNA_pol3_beta. 1 hit.
PF02767. DNA_pol3_beta_2. 1 hit.
PF02768. DNA_pol3_beta_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000804. DNA_pol_III_b. 1 hit.
SMARTiSM00480. POL3Bc. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00663. dnan. 1 hit.

Sequencei

Sequence statusi: Complete.

P72856-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKLICRQSDL SSGLSLVSRA VSSRPTHPVL GNVLLEADAD KNYLRLTAFD
60 70 80 90 100
LSLGIQSSFT ADVQQSGRIT LPAKLLNDIV SRLPDGDITL AIDPDGDAGD
110 120 130 140 150
SHLTTITSES GRFQIRGLDA DDFPALPTVE GVKPLLLPVA TLNEGLRGAL
160 170 180 190 200
FAASTDETKQ VLTGVHIKGS GDSLEFAATD GHRLAVVEAP TQIENDEGEA
210 220 230 240 250
VITGSDLADF AVTIPARALR ELERMVASQG NSDLVSLVVN DTQVIFELGD
260 270 280 290 300
QRLTSRKLEG AYPAYDQLIP RQFSRTVTME RKRLITSLER VSVLADQKNN
310 320 330 340 350
LVTFTLQSPG NQLQLAVEAQ DLGHGEESMG AEIIGEGGQI AFNIKYLMDG
360 370 380 390
LKALPSNDIQ MQLNEGNQPV IFTPLGGLKM TYLVMPVRLV N
Length:391
Mass (Da):42,088
Last modified:February 1, 1997 - v1
Checksum:i5FA9942EE1C7A7E9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA16871.1.
PIRiS74720.
RefSeqiNP_440191.1. NC_000911.1.
YP_005650248.1. NC_017277.1.
YP_007450074.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA16871; BAA16871; BAA16871.
GeneIDi953490.
KEGGisyn:slr0965.
PATRICi23837508. VBISynSp132158_0325.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA16871.1 .
PIRi S74720.
RefSeqi NP_440191.1. NC_000911.1.
YP_005650248.1. NC_017277.1.
YP_007450074.1. NC_020286.1.

3D structure databases

ProteinModelPortali P72856.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 1148.slr0965.

Proteomic databases

PaxDbi P72856.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA16871 ; BAA16871 ; BAA16871 .
GeneIDi 953490.
KEGGi syn:slr0965.
PATRICi 23837508. VBISynSp132158_0325.

Phylogenomic databases

eggNOGi COG0592.
HOGENOMi HOG000071791.
InParanoidi P72856.
KOi K02338.
OMAi VCGLNGH.
OrthoDBi EOG65J53F.
PhylomeDBi P72856.

Family and domain databases

InterProi IPR001001. DNA_polIII_beta.
IPR022635. DNA_polIII_beta_C.
IPR022637. DNA_polIII_beta_cen.
IPR022634. DNA_polIII_beta_N.
[Graphical view ]
Pfami PF00712. DNA_pol3_beta. 1 hit.
PF02767. DNA_pol3_beta_2. 1 hit.
PF02768. DNA_pol3_beta_3. 1 hit.
[Graphical view ]
PIRSFi PIRSF000804. DNA_pol_III_b. 1 hit.
SMARTi SM00480. POL3Bc. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00663. dnan. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiDPO3B_SYNY3
AccessioniPrimary (citable) accession number: P72856
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: November 26, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3