P72794 (CYSH_SYNY3) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 79.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Phosphoadenosine phosphosulfate reductase EC=1.8.4.8 Alternative name(s): 3'-phosphoadenylylsulfate reductase PAPS reductase, thioredoxin dependent PAPS sulfotransferase PAdoPS reductase | ||||
| Gene names |
| ||||
| Organism | Synechocystis sp. (strain PCC 6803 / Kazusa) | ||||
| Taxonomic identifier | 1111708 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Cyanobacteria › Chroococcales › Synechocystis |
Protein attributes
| Sequence length | 249 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Reduction of activated sulfate into sulfite. HAMAP MF_00063 |
| Catalytic activity | Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin. HAMAP MF_00063 |
| Pathway | Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3. HAMAP MF_00063 |
| Subcellular location | Cytoplasm By similarity HAMAP MF_00063. |
| Sequence similarities | Belongs to the PAPS reductase family. CysH subfamily. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | cysteine biosynthetic process Inferred from electronic annotation. Source: InterPro sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)Inferred from electronic annotation. Source: InterPro |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | phosphoadenylyl-sulfate reductase (thioredoxin) activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 249 | 249 | Phosphoadenosine phosphosulfate reductase HAMAP MF_00063 | PRO_0000100650 | |||
Sequences
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References
| [1] | "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. Tabata S.DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27184 / PCC 6803 / N-1. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BA000022 Genomic DNA. Translation: BAA16809.1. |
| PIR | S74657. |
| RefSeq | NP_440129.1. NC_000911.1. |
3D structure databases | |
| ProteinModelPortal | P72794. |
| ModBase | Search... |
Protein-protein interaction databases | |
| IntAct | P72794. 1 interaction. |
| STRING | P72794. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 953428. |
| GenomeReviews | Gene locus slr1791 in contig BA000022_GR. |
| KEGG | syn:slr1791. |
| NMPDR | fig|1148.1.peg.230. |
| PATRIC | 23837354. VBISynSp132158_0251. |
Phylogenomic databases | |
| eggNOG | COG0175. |
| HOGENOM | HBG758022. |
| OMA | AIHGTRF. |
| PhylomeDB | P72794. |
| ProtClustDB | PRK02090. |
Enzyme and pathway databases | |
| BioCyc | SSP1148:SLR1791-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00063. CysH. [Tree] |
| InterPro | IPR004511. PAPS/APS_Rdtase. IPR002500. PAPS_reduct. IPR011800. PAPS_reductase_CysH. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view] |
| Gene3D | G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit. |
| KO | K00390. |
| Pfam | PF01507. PAPS_reduct. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR00434. CysH. 1 hit. TIGR02057. PAPS_reductase. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | CYSH_SYNY3 | ||||||||
| Accession | Primary (citable) accession number: P72794 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| Synechocystis PCC 6803 Synechocystis (strain PCC 6803): entries and gene names |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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