Skip Header

 
Contribute Send feedback

Reviewed, UniProtKB/Swiss-Prot P72794 (CYSH_SYNY3)

Last modified November 25, 2008. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Phosphoadenosine phosphosulfate reductase
    EC=1.8.4.8
Alternative name(s):
    PAPS reductase, thioredoxin dependent
    PAdoPS reductase
    3'-phosphoadenylylsulfate reductase
    PAPS sulfotransferase
Gene names
Name: cysH
Ordered Locus Names: slr1791
OrganismSynechocystis sp. (strain PCC 6803) [Complete proteome] [HAMAP]
Taxonomic identifier1148 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaChroococcalesSynechocystis

Protein attributes

Sequence length249 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Reduction of activated sulfate into sulfite.

Catalytic activity

Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin.

Pathway

Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3.

Subcellular location

CytoplasmBy similarity.

Sequence similarities

Belongs to the PAPS reductase family. CysH subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 249249Phosphoadenosine phosphosulfate reductase
PRO_0000100650

Sequences

Sequence LengthMass (Da)Tools
P72794-1 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 3632FCF2DC669BF7

FASTA24928,468
        10         20         30         40         50         60 
MSHTLTKLDL PTLQTELENA TAQQIITWAA QTFGPGLVMS TSFGIQAAVM LHLVTSIVPN 

        70         80         90        100        110        120 
IPVIWIDTGY LPLETYQFAD QLTGRLQLNL KVYQSPLSPA RMEALYGKLW QQKDVESLNR 

       130        140        150        160        170        180 
YDQIRKVEPM QRALKELEAI AWLTGLRRDQ TRHRQNLKPV DLQGNQYKVL PILDWNSKMV 

       190        200        210        220        230        240 
YEYLTAHDLP YHPFFDQGYV SVGDWHSSRP LMAHDEDERD TRFHGLKQEC GLHLPLSPEA 


GQSLDSSAL 

« Hide

References

[1]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

BA000022 Genomic DNA. Translation: BAA16809.1.
PIRS74657.
RefSeqNP_440129.1.

3D structure databases

HSSPHSSP built from PDB template 1SUR based on UniProtKB P17854.
ModBaseSearch...

Protein-protein interaction databases

IntActP72794.

Genome annotation databases

GeneID953428.
GenomeReviewsGene locus slr1791 in contig BA000022_GR.
KEGGsyn:slr1791.
NMPDRfig|1148.1.peg.230.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMP72794.

Enzyme and pathway databases

BioCycSSP1148:SLR1791-MON.

Family and domain databases

HAMAPMF_00063.
[Tree]
InterProIPR004511. CysH.
IPR002500. PAPS_reduct.
IPR011800. PAPS_reductase.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
Gene3DG3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PfamPF01507. PAPS_reduct. 1 hit.
[Graphical view]
TIGRFAMsTIGR00434. cysH. 1 hit.
TIGR02057. PAPS_reductase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCYSH_SYNY3
AccessionPrimary (citable) accession number: P72794
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: November 25, 2008
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents