P72704 (PPI1_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable peptidyl-prolyl cis-trans isomerase sll0227
Short name=PPIase sll0227
EC=5.2.1.8

Alternative name(s):
Rotamase sll0227

Gene names

Ordered Locus Names:

sll0227

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa)

Taxonomic identifier

1111708 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechocystis

Protein attributes

Sequence length	246 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Catalytic activity	Peptidylproline (omega=180) = peptidylproline (omega=0).
Sequence similarities	Belongs to the cyclophilin-type PPIase family. Contains 1 PPIase cyclophilin-type domain.

Ontologies

Keywords
Domain	Signal
Molecular function	Isomerase Rotamase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	protein folding Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	outer membrane-bounded periplasmic space Inferred from direct assay. Source: UniProtKB
Molecular function	peptidyl-prolyl cis-trans isomerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 36	36	Potential
	Chain	37 – 246	210	Probable peptidyl-prolyl cis-trans isomerase sll0227		PRO_0000025502
Regions
	Domain	64 – 246	183	PPIase cyclophilin-type

Sequences

	Sequence		Length	Mass (Da)
	P72704 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 02080EE3C339932F	FASTA	246	26,580
	10 20 30 40 50 60 MRILPNISRA TWFVGIFFVV NILLTACNQP SANSSAEPSP TETNSPVAQV TTDPYKDYKP 70 80 90 100 110 120 RLNGKATVEM MVNGQPIIIE VDGENAPITA GNFVDLVEQG FYNGLTFHRV VDGFVAQGGD 130 140 150 160 170 180 PKGDGTGGYV DKNTQRPRNI PLEIKVDPAV ENAPETPVYS RALGNQAGFP VMLPHKTGAV 190 200 210 220 230 240 AMARSQMPDS ASSQFYFTLS DETGFLDGDY AVFGYVTQGM DVVLKIKQGD KIQSAKVITG QNNLEK

References

[1]

"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27184 / PCC 6803 / N-1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000022 Genomic DNA. Translation: BAA16711.1.
PIR	S74559.
RefSeq	NP_440031.1. NC_000911.1.
3D structure databases
ProteinModelPortal	P72704.
ModBase	Search...
Protein-protein interaction databases
STRING	P72704.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	953328.
GenomeReviews	Gene locus sll0227 in contig BA000022_GR.
KEGG	syn:sll0227.
NMPDR	fig|1148.1.peg.132.
PATRIC	23837140. VBISynSp132158_0145.
Phylogenomic databases
eggNOG	COG0652.
HOGENOM	HBG610621.
OMA	QPFVVQG.
PhylomeDB	P72704.
Enzyme and pathway databases
BioCyc	SSP1148:SLL0227-MONOMER.
Family and domain databases
InterPro	IPR002130. Cyclophilin-like_PPIase_dom. IPR020892. Cyclophilin-type_PPIase_CS. [Graphical view]
Gene3D	G3DSA:2.40.100.10. PPIase_cyclophilin. 1 hit.
KO	K03768.
Pfam	PF00160. Pro_isomerase. 1 hit. [Graphical view]
PRINTS	PR00153. CSAPPISMRASE.
SUPFAM	SSF50891. CSA_PPIase. 1 hit.
PROSITE	PS00170. CSA_PPIASE_1. 1 hit. PS50072. CSA_PPIASE_2. 1 hit. PS51257. PROKAR_LIPOPROTEIN. 1 hit. Uncertain. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PPI1_SYNY3

Accession

Primary (citable) accession number: P72704

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 17, 2003
Last sequence update:	February 1, 1997
Last modified:	January 25, 2012
This is version 73 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program