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P72703 (SPEB1_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Agmatinase 1

EC=3.5.3.11
Alternative name(s):
Agmatine ureohydrolase 1
Short name=AUH 1
Gene names
Name:speB1
Ordered Locus Names:sll0228
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length306 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Agmatine + H2O = putrescine + urea.

Cofactor

Manganese Potential.

Sequence similarities

Belongs to the arginase family. Agmatinase subfamily.

Caution

Was originally annotated as an arginase by the genome sequencing project.

Ontologies

Keywords
   Biological processPutrescine biosynthesis
   LigandManganese
Metal-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processputrescine biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionagmatinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 306306Agmatinase 1
PRO_0000173744

Sites

Metal binding1211Manganese By similarity
Metal binding1451Manganese By similarity
Metal binding1471Manganese By similarity
Metal binding1491Manganese By similarity
Metal binding2281Manganese By similarity
Metal binding2301Manganese By similarity

Sequences

Sequence LengthMass (Da)Tools
P72703 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 114A8A313A0C4605

FASTA30633,463
        10         20         30         40         50         60 
MHSPNKFTSG PKQFLESEAI TSYADAAVVV VPIPYEATTS YRKGCEHGPE AVLEASDQLE 

        70         80         90        100        110        120 
AYDEELGTSP CHDLGIYTCA PLADSNKHPA LAGDAMVTEV CDGIAPFVED GKFVVAIGGE 

       130        140        150        160        170        180 
HAITTGVVRA MQRGTSEPFT VVQIDAHGDM RDKFEGSCHN HACVMRRVLE LGLPTLPIAI 

       190        200        210        220        230        240 
RAICQEEADL IREKNIPVFW AREMADNPNW INEAIASITT QKVFLTIDMD GFDPGFMPGV 

       250        260        270        280        290        300 
GTPEPGGLGW YEGLNFFRRL FQTKQVIGCD LMELAPVRGS VVSEFSTAKL AYKLMGYWGE 


SQRKKL 

« Hide

References

« Hide 'large scale' references
[1]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.
[2]"Arginine catabolism in the cyanobacterium Synechocystis sp. strain PCC 6803 involves the urea cycle and arginase pathway."
Quintero M.J., Muro-Pastor A.M., Herrero A., Flores E.
J. Bacteriol. 182:1008-1015(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000022 Genomic DNA. Translation: BAA16710.1.
PIRS74558.
RefSeqNP_440030.1. NC_000911.1.
YP_005650087.1. NC_017277.1.
YP_007449913.1. NC_020286.1.

3D structure databases

ProteinModelPortalP72703.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP72703. 1 interaction.
STRING1148.sll0228.

Proteomic databases

PaxDbP72703.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA16710; BAA16710; BAA16710.
GeneID12253920.
14615554.
953327.
KEGGsyn:sll0228.
syy:SYNGTS_0134.
syz:MYO_11320.
PATRIC23837138. VBISynSp132158_0144.

Phylogenomic databases

eggNOGCOG0010.
KOK01480.
OMAKGADKGP.
OrthoDBEOG6SR905.
PhylomeDBP72703.
ProtClustDBCLSK892499.

Family and domain databases

Gene3D3.40.800.10. 1 hit.
InterProIPR005925. Agmatinase-rel.
IPR006035. Ureohydrolase.
IPR023696. Ureohydrolase_domain.
IPR020855. Ureohydrolase_Mn_BS.
[Graphical view]
PANTHERPTHR11358. PTHR11358. 1 hit.
PfamPF00491. Arginase. 1 hit.
[Graphical view]
PIRSFPIRSF036979. Arginase. 1 hit.
TIGRFAMsTIGR01230. agmatinase. 1 hit.
PROSITEPS01053. ARGINASE_1. 1 hit.
PS51409. ARGINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSPEB1_SYNY3
AccessionPrimary (citable) accession number: P72703
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: February 1, 1997
Last modified: April 16, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families