P72656 (RNE_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease E homolog
Short name=RNase E
EC=3.1.26.12

Gene names

Name:	rne
Ordered Locus Names:	slr1129

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]

Taxonomic identifier

1111708 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Synechocystis › Synechocystis sp. PCC 6803

Protein attributes

Sequence length	674 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Endonucleolytic cleavage of single-stranded RNA in A- and U-rich regions.
Sequence similarities	Belongs to the RNase E/G family. RNase E subfamily. Contains 1 S1 motif domain.

Ontologies

Keywords
Molecular function	Endonuclease Hydrolase Nuclease
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	RNA processing Inferred from electronic annotation. Source: InterPro nucleic acid phosphodiester bond hydrolysis Inferred from electronic annotation. Source: GOC
Molecular_function	RNA binding Inferred from electronic annotation. Source: InterPro endonuclease activity Inferred from electronic annotation. Source: UniProtKB-KW ribonuclease activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 674	674	Ribonuclease E homolog		PRO_0000097378
Regions
	Domain	35 – 117	83	S1 motif

Sequences

	Sequence		Length	Mass (Da)
	P72656 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 5C03F6087596C2B5	FASTA	674	74,944
	10 20 30 40 50 60 MPKQIVIAEK HQVAAVFWKD QIQELVVSTG SQQVGDIYLG LVDNILPSID AAFINIGDTE 70 80 90 100 110 120 KNGFIHVSDL GPVRLRRTAG SISELLSPQQ RVLVQVMKEP TGNKGPRLTG NISMPGRYMV 130 140 150 160 170 180 LMPYGRGVNL SRRINREEER SRLRALAVLI KPPGMGLLVR TEAEDVPEDA IIEDLENLQK 190 200 210 220 230 240 QWELVQQQAM TRSAPMLLDR DDDFIKRVLR DMYSSEVNRI VVDTPAGMKR IKQQLMNWDQ 250 260 270 280 290 300 GRLPEGVLID CHRESLSILE YFRVNATIRE ALKPRVDLPS GGYIIIEPTE ALTVIDVNSG 310 320 330 340 350 360 SFTHSANSRE TVLWTNYEAA TEIARQLKLR NIGGVIIIDF IDMDSHKDQL QLLEHFNRCL 370 380 390 400 410 420 ETDKARPQIA QLTELGLVEL TRKRQGQNLY ELFGQPCPEC GGLGHLVELP GEKGFVSLSP 430 440 450 460 470 480 TAVNSSIPPR LVEKPILSPP VAKVNDLPKK EEAKISSPLD LLFHPNYQEQ GDRDSNRRRR 490 500 510 520 530 540 RRRGSEFSEK ENIKSVGISR SKGPSPSPTK EKVTGTAPPR RERPSRRVEK TLVPVDVAMT 550 560 570 580 590 600 TLEQDIYARM GISPLIKTEY ADQDPRSFMV SVVTAGAALE GNTNGSGSLV NAVITTVDNG 610 620 630 640 650 660 DNGDNVPSDG LTIVSEVTAP TPVIEQPREE TVEPEQVVLP QLDDETPAAP VAEESAPIET 670 KKRPGRRRRR SSAE

References

[1]

"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000022 Genomic DNA. Translation: BAA16658.1.
PIR	S74506.
RefSeq	NP_439978.1. NC_000911.1. YP_005650033.1. NC_017277.1. YP_007449861.1. NC_020286.1.
3D structure databases
ProteinModelPortal	P72656.
ModBase	Search...
Protein-protein interaction databases
IntAct	P72656. 7 interactions.
STRING	1148.slr1129.
Proteomic databases
PaxDb	P72656.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAA16658; BAA16658; BAA16658.
GeneID	12253786. 14615502. 953139.
KEGG	syn:slr1129. syy:SYNGTS_0080.
PATRIC	23837026. VBISynSp132158_0088.
Phylogenomic databases
eggNOG	COG1530.
HOGENOM	HOG000233194.
KO	K08300.
OMA	TEKNGFI.
ProtClustDB	CLSK892469.
Family and domain databases
Gene3D	2.40.50.140. 1 hit.
InterPro	IPR012340. NA-bd_OB-fold. IPR003029. Rbsml_prot_S1_RNA-bd_dom. IPR019307. RNA-bd_AU-1/RNase_E/G. IPR022967. RNA-binding_domain_S1. IPR004659. RNase_E/G. [Graphical view]
Pfam	PF10150. RNase_E_G. 1 hit. PF00575. S1. 1 hit. [Graphical view]
SMART	SM00316. S1. 1 hit. [Graphical view]
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit.
TIGRFAMs	TIGR00757. RNaseEG. 1 hit.
PROSITE	PS50126. S1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RNE_SYNY3

Accession

Primary (citable) accession number: P72656

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	February 1, 1997
Last modified:	May 1, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program