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P72648

- KGUA_SYNY3

UniProt

P72648 - KGUA_SYNY3

Protein

Guanylate kinase

Gene

gmk

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 1 (01 Feb 1997)
      Previous versions | rss
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    Functioni

    Essential for recycling GMP and indirectly, cGMP.By similarity

    Catalytic activityi

    ATP + GMP = ADP + GDP.

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi17 – 248ATPBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. guanylate kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. purine nucleotide metabolic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Guanylate kinase (EC:2.7.4.8)
    Alternative name(s):
    GMP kinase
    Gene namesi
    Name:gmk
    Ordered Locus Names:slr1123
    OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
    Taxonomic identifieri1111708 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
    ProteomesiUP000001425: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 191191Guanylate kinasePRO_0000170629Add
    BLAST

    Proteomic databases

    PaxDbiP72648.

    Interactioni

    Protein-protein interaction databases

    STRINGi1148.slr1123.

    Structurei

    3D structure databases

    ProteinModelPortaliP72648.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini10 – 188179Guanylate kinase-likeAdd
    BLAST

    Sequence similaritiesi

    Belongs to the guanylate kinase family.Curated
    Contains 1 guanylate kinase-like domain.Curated

    Phylogenomic databases

    eggNOGiCOG0194.
    HOGENOMiHOG000037640.
    KOiK00942.
    OMAiDAVFSIS.
    OrthoDBiEOG6CP410.
    PhylomeDBiP72648.

    Family and domain databases

    Gene3Di3.40.50.300. 3 hits.
    HAMAPiMF_00328. Guanylate_kinase.
    InterProiIPR008145. GK/Ca_channel_bsu.
    IPR008144. Guanylate_kin-like.
    IPR017665. Guanylate_kinase.
    IPR020590. Guanylate_kinase_CS.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF00625. Guanylate_kin. 1 hit.
    [Graphical view]
    SMARTiSM00072. GuKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
    PROSITEiPS00856. GUANYLATE_KINASE_1. 1 hit.
    PS50052. GUANYLATE_KINASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P72648-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAPDQTSVKG QLIVLTGPSG VGKGTLVQLL LERQPHWFLS ISATTRSPRA    50
    GEVDGQSYYF LTKEEFQTWI GEEKLLEWAE YAGNYYGTPR QPVEEQIAQG 100
    KTVLLEIEVL GARQIKQTFP SARRIFILPP SVEVLEERLR GRGSDSETAI 150
    AKRLAQAQQE LQAAAEFDYQ VVNDDLDQAL HRLVKLIGEE E 191
    Length:191
    Mass (Da):21,427
    Last modified:February 1, 1997 - v1
    Checksum:iE92B5FCC6602FBB9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000022 Genomic DNA. Translation: BAA16650.1.
    PIRiS74498.
    RefSeqiNP_439970.1. NC_000911.1.
    YP_005650025.1. NC_017277.1.
    YP_007449853.1. NC_020286.1.

    Genome annotation databases

    EnsemblBacteriaiBAA16650; BAA16650; BAA16650.
    GeneIDi953117.
    KEGGisyn:slr1123.
    syy:SYNGTS_0072.
    syz:MYO_1720.
    PATRICi23837010. VBISynSp132158_0080.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000022 Genomic DNA. Translation: BAA16650.1 .
    PIRi S74498.
    RefSeqi NP_439970.1. NC_000911.1.
    YP_005650025.1. NC_017277.1.
    YP_007449853.1. NC_020286.1.

    3D structure databases

    ProteinModelPortali P72648.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 1148.slr1123.

    Proteomic databases

    PaxDbi P72648.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAA16650 ; BAA16650 ; BAA16650 .
    GeneIDi 953117.
    KEGGi syn:slr1123.
    syy:SYNGTS_0072.
    syz:MYO_1720.
    PATRICi 23837010. VBISynSp132158_0080.

    Phylogenomic databases

    eggNOGi COG0194.
    HOGENOMi HOG000037640.
    KOi K00942.
    OMAi DAVFSIS.
    OrthoDBi EOG6CP410.
    PhylomeDBi P72648.

    Family and domain databases

    Gene3Di 3.40.50.300. 3 hits.
    HAMAPi MF_00328. Guanylate_kinase.
    InterProi IPR008145. GK/Ca_channel_bsu.
    IPR008144. Guanylate_kin-like.
    IPR017665. Guanylate_kinase.
    IPR020590. Guanylate_kinase_CS.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF00625. Guanylate_kin. 1 hit.
    [Graphical view ]
    SMARTi SM00072. GuKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR03263. guanyl_kin. 1 hit.
    PROSITEi PS00856. GUANYLATE_KINASE_1. 1 hit.
    PS50052. GUANYLATE_KINASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
      Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
      , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
      DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PCC 6803 / Kazusa.

    Entry informationi

    Entry nameiKGUA_SYNY3
    AccessioniPrimary (citable) accession number: P72648
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Synechocystis PCC 6803
      Synechocystis (strain PCC 6803): entries and gene names

    External Data

    Dasty 3