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P72648

- KGUA_SYNY3

UniProt

P72648 - KGUA_SYNY3

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Protein
Guanylate kinase
Gene
gmk, slr1123
Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP By similarity.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi17 – 248ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. guanylate kinase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. purine nucleotide metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinase (EC:2.7.4.8)
Alternative name(s):
GMP kinase
Gene namesi
Name:gmk
Ordered Locus Names:slr1123
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 191191Guanylate kinaseUniRule annotation
PRO_0000170629Add
BLAST

Proteomic databases

PaxDbiP72648.

Interactioni

Protein-protein interaction databases

STRINGi1148.slr1123.

Structurei

3D structure databases

ProteinModelPortaliP72648.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini10 – 188179Guanylate kinase-like
Add
BLAST

Sequence similaritiesi

Belongs to the guanylate kinase family.

Phylogenomic databases

eggNOGiCOG0194.
HOGENOMiHOG000037640.
KOiK00942.
OMAiDAVFSIS.
OrthoDBiEOG6CP410.
PhylomeDBiP72648.

Family and domain databases

Gene3Di3.40.50.300. 3 hits.
HAMAPiMF_00328. Guanylate_kinase.
InterProiIPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00625. Guanylate_kin. 1 hit.
[Graphical view]
SMARTiSM00072. GuKc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiPS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P72648-1 [UniParc]FASTAAdd to Basket

« Hide

MAPDQTSVKG QLIVLTGPSG VGKGTLVQLL LERQPHWFLS ISATTRSPRA    50
GEVDGQSYYF LTKEEFQTWI GEEKLLEWAE YAGNYYGTPR QPVEEQIAQG 100
KTVLLEIEVL GARQIKQTFP SARRIFILPP SVEVLEERLR GRGSDSETAI 150
AKRLAQAQQE LQAAAEFDYQ VVNDDLDQAL HRLVKLIGEE E 191
Length:191
Mass (Da):21,427
Last modified:February 1, 1997 - v1
Checksum:iE92B5FCC6602FBB9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000022 Genomic DNA. Translation: BAA16650.1.
PIRiS74498.
RefSeqiNP_439970.1. NC_000911.1.
YP_005650025.1. NC_017277.1.
YP_007449853.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA16650; BAA16650; BAA16650.
GeneIDi953117.
KEGGisyn:slr1123.
syy:SYNGTS_0072.
syz:MYO_1720.
PATRICi23837010. VBISynSp132158_0080.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000022 Genomic DNA. Translation: BAA16650.1 .
PIRi S74498.
RefSeqi NP_439970.1. NC_000911.1.
YP_005650025.1. NC_017277.1.
YP_007449853.1. NC_020286.1.

3D structure databases

ProteinModelPortali P72648.
ModBasei Search...

Protein-protein interaction databases

STRINGi 1148.slr1123.

Proteomic databases

PaxDbi P72648.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA16650 ; BAA16650 ; BAA16650 .
GeneIDi 953117.
KEGGi syn:slr1123.
syy:SYNGTS_0072.
syz:MYO_1720.
PATRICi 23837010. VBISynSp132158_0080.

Phylogenomic databases

eggNOGi COG0194.
HOGENOMi HOG000037640.
KOi K00942.
OMAi DAVFSIS.
OrthoDBi EOG6CP410.
PhylomeDBi P72648.

Family and domain databases

Gene3Di 3.40.50.300. 3 hits.
HAMAPi MF_00328. Guanylate_kinase.
InterProi IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF00625. Guanylate_kin. 1 hit.
[Graphical view ]
SMARTi SM00072. GuKc. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR03263. guanyl_kin. 1 hit.
PROSITEi PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiKGUA_SYNY3
AccessioniPrimary (citable) accession number: P72648
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: July 9, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3

Similar proteinsi