Reviewed, UniProtKB/Swiss-Prot P72641 (KAD2_SYNY3)

Names and origin

Protein names

Recommended name:
    Probable adenylate kinase 2
      Short name=AK 2
    EC=2.7.4.3
Alternative name(s):
    ATP-AMP transphosphorylase 2

Gene names

Name:	adk2
Ordered Locus Names:	sll1059

Organism

Synechocystis sp. (strain PCC 6803) [Complete proteome] [HAMAP]

Taxonomic identifier

1148 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechocystis

Protein attributes

Sequence length	181 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	This small ubiquitous enzyme is essential for maintenance and cell growth. HAMAP MF_00235
Catalytic activity	ATP + AMP = 2 ADP. HAMAP MF_00235
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the adenylate kinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP adenylate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 181	181	Probable adenylate kinase 2 HAMAP MF_00235		PRO_0000158872
Regions
	Nucleotide binding	7 – 15	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	P72641-1 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 3935871CA87958EE	FASTA	181	20,340
	10 20 30 40 50 60 MRLVMLGGPG SGKSTQSHNL SQELKLPVIS MGGILREAIA NATPLGIKAK PYVERGDLLP 70 80 90 100 110 120 DPMMIEFIQQ RLVQEDGGQG WILEGYPRTA FQAEELDFLL EDLGQPLDWA LYLKIDEATM 130 140 150 160 170 180 VERSLNRSLF DDHPEAITTR IGKFHEYTVP LLEYYAAKQN LLTVNAYPEV DQVTKLILAR L

References

[1]

"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000022 Genomic DNA. Translation: BAA16643.1.
PIR	S74491.
RefSeq	NP_439963.1.
3D structure databases
HSSP	HSSP built from PDB template 1ZIN based on UniProtKB P27142.
ModBase	Search...
Genome annotation databases
GeneID	952893.
GenomeReviews	Gene locus sll1059 in contig BA000022_GR.
KEGG	syn:sll1059.
NMPDR	fig|1148.1.peg.64.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P72641.
OMA	P72641. RTIPILE.
Enzyme and pathway databases
BioCyc	SSP1148:SLL1059-MON.
Family and domain databases
HAMAP	MF_00235. [Tree]
InterPro	IPR000850. Adenylate_kin. [Graphical view]
PANTHER	PTHR23359. Adenylate_kin. 1 hit.
Pfam	PF00406. ADK. 1 hit. [Graphical view]
PRINTS	PR00094. ADENYLTKNASE.
ProDom	PD000657. Adenylate_kin. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00113. ADENYLATE_KINASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

KAD2_SYNY3

Accession

Primary (citable) accession number: P72641

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 27, 2002
Last sequence update:	February 1, 1997
Last modified:	June 16, 2009
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)