P72584 (ACSF1_SYNY3) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 1, 2013.
Version 89.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase 1 Short name=Mg-protoporphyrin IX monomethyl ester oxidative cyclase 1 EC=1.14.13.81 | ||||
| Gene names |
| ||||
| Organism | Synechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP] | ||||
| Taxonomic identifier | 1111708 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Synechocystis › ![]() |
Protein attributes
| Sequence length | 358 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) By similarity. HAMAP-Rule MF_01840 |
| Catalytic activity | Magnesium-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 O2 = divinylprotochlorophyllide + 3 NADP+ + 5 H2O. HAMAP-Rule MF_01840 |
| Cofactor | Iron By similarity. |
| Pathway | Porphyrin biosynthesis; chlorophyll biosynthesis (light-independent). HAMAP-Rule MF_01840 |
| Sequence similarities | Belongs to the AcsF family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Chlorophyll biosynthesis Photosynthesis |
| Ligand | Iron Metal-binding NADP |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological_process | light-independent chlorophyll biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway photosynthesisInferred from electronic annotation. Source: HAMAP |
| Molecular_function | iron ion binding Inferred from electronic annotation. Source: HAMAP magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activityInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 358 | 358 | Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase 1 HAMAP-Rule MF_01840 | PRO_0000217539 | |||
Sequences
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References
| [1] | "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. Tabata S.DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 6803 / Kazusa. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | BA000022 Genomic DNA. Translation: BAA16583.1. |
| PIR | S74431. |
| RefSeq | NP_439903.1. NC_000911.1. YP_005649958.1. NC_017277.1. YP_007449786.1. NC_020286.1. |
3D structure databases | |
| ProteinModelPortal | P72584. |
| ModBase | Search... |
Protein-protein interaction databases | |
| IntAct | P72584. 8 interactions. |
| STRING | 1148.sll1214. |
Proteomic databases | |
| PaxDb | P72584. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | BAA16583; BAA16583; BAA16583. |
| GeneID | 12255294. 14615427. 951877. |
| KEGG | syn:sll1214. syy:SYNGTS_0005. |
| PATRIC | 23836862. VBISynSp132158_0006. |
Phylogenomic databases | |
| eggNOG | NOG10633. |
| HOGENOM | HOG000233491. |
| KO | K04035. |
| OMA | NPLLAEC. |
| ProtClustDB | PRK13654. |
Enzyme and pathway databases | |
| BioCyc | MetaCyc:MONOMER-17787. |
| UniPathway | UPA00670. |
Family and domain databases | |
| HAMAP | MF_01840. AcsF. |
| InterPro | IPR008434. AcsF. IPR009078. Ferritin-like_SF. IPR003251. Rubrerythrin. [Graphical view] |
| Pfam | PF02915. Rubrerythrin. 1 hit. [Graphical view] |
| SUPFAM | SSF47240. Ferritin/RR_like. 1 hit. |
| TIGRFAMs | TIGR02029. AcsF. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | ACSF1_SYNY3 | ||||||||
| Accession | Primary (citable) accession number: P72584 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| Synechocystis PCC 6803 Synechocystis (strain PCC 6803): entries and gene names |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with
