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Protein

C-phycocyanin alpha chain

Gene

cpcA

Organism
Arthrospira platensis (Spirulina platensis)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei84Phycocyanobilin chromophore (covalent; via 1 link)1

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Photosynthesis, Transport

Keywords - Ligandi

Bile pigment, Chromophore

Names & Taxonomyi

Protein namesi
Recommended name:
C-phycocyanin alpha chain
Gene namesi
Name:cpcA
OrganismiArthrospira platensis (Spirulina platensis)
Taxonomic identifieri118562 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeOscillatorialesMicrocoleaceaeArthrospira

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Phycobilisome, Thylakoid

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001991271 – 162C-phycocyanin alpha chainAdd BLAST162

Post-translational modificationi

Contains one covalently linked phycocyanobilin chromophore.

Interactioni

Subunit structurei

The alpha and beta chains exhibit high affinity for one another and form heterodimers. These heterodimers form heterohexamers of 3 alpha and 3 beta chains which, in turn, aggregate into a heterododecamer consisting of 2 heterohexamers.

Protein-protein interaction databases

STRINGi696747.NIES39_D02050.

Structurei

Secondary structure

1162
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi4 – 14Combined sources11
Helixi21 – 46Combined sources26
Helixi48 – 62Combined sources15
Helixi65 – 68Combined sources4
Helixi78 – 101Combined sources24
Helixi105 – 110Combined sources6
Turni111 – 114Combined sources4
Helixi115 – 121Combined sources7
Helixi126 – 139Combined sources14
Helixi144 – 160Combined sources17

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1GH0X-ray2.20A/C/E/G/I/K/M/O/Q/S/U/W1-162[»]
1HA7X-ray2.20A/C/E/G/I/K/M/O/Q/S/U/W1-162[»]
2UUMX-ray3.00A/C/E/G/I/K/M/O/Q/S/U/W1-162[»]
ProteinModelPortaliP72509.
SMRiP72509.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP72509.

Family & Domainsi

Sequence similaritiesi

Belongs to the phycobiliprotein family.Curated

Phylogenomic databases

eggNOGiENOG4108SDR. Bacteria.
ENOG4111FZC. LUCA.

Family and domain databases

Gene3Di1.10.490.20. 1 hit.
InterProiIPR009050. Globin-like.
IPR012128. Phycobilisome_asu/bsu.
IPR006246. Phycocyanin_a.
[Graphical view]
PfamiPF00502. Phycobilisome. 1 hit.
[Graphical view]
PIRSFiPIRSF000081. Phycocyanin. 1 hit.
SUPFAMiSSF46458. SSF46458. 1 hit.
TIGRFAMsiTIGR01338. phycocy_alpha. 1 hit.

Sequencei

Sequence statusi: Complete.

P72509-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTPLTEAVS IADSQGRFLS STEIQVAFGR FRQAKAGLEA AKALTSKADS
60 70 80 90 100
LISGAAQAVY NKFPYTTQMQ GPNYAADQRG KDKCARDIGY YLRMVTYCLI
110 120 130 140 150
AGGTGPMDEY LIAGIDEINR TFELSPSWYI EALKYIKANH GLSGDAATEA
160
NSYLDYAINA LS
Length:162
Mass (Da):17,602
Last modified:June 20, 2001 - v2
Checksum:iDA87ED20CBD2C354
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti51L → R in CAA70296 (Ref. 1) Curated1
Sequence conflicti148T → G in CAA70296 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y09074 Genomic DNA. Translation: CAA70296.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y09074 Genomic DNA. Translation: CAA70296.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1GH0X-ray2.20A/C/E/G/I/K/M/O/Q/S/U/W1-162[»]
1HA7X-ray2.20A/C/E/G/I/K/M/O/Q/S/U/W1-162[»]
2UUMX-ray3.00A/C/E/G/I/K/M/O/Q/S/U/W1-162[»]
ProteinModelPortaliP72509.
SMRiP72509.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi696747.NIES39_D02050.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4108SDR. Bacteria.
ENOG4111FZC. LUCA.

Miscellaneous databases

EvolutionaryTraceiP72509.

Family and domain databases

Gene3Di1.10.490.20. 1 hit.
InterProiIPR009050. Globin-like.
IPR012128. Phycobilisome_asu/bsu.
IPR006246. Phycocyanin_a.
[Graphical view]
PfamiPF00502. Phycobilisome. 1 hit.
[Graphical view]
PIRSFiPIRSF000081. Phycocyanin. 1 hit.
SUPFAMiSSF46458. SSF46458. 1 hit.
TIGRFAMsiTIGR01338. phycocy_alpha. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPHCA_ARTPT
AccessioniPrimary (citable) accession number: P72509
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: June 20, 2001
Last modified: November 2, 2016
This is version 83 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.