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Protein
Submitted name:

CooA protein

Gene

cooA

Organism
Rhodospirillum rubrum
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi2 – 21Iron (heme axial ligand); via amide nitrogenCombined sources
Metal bindingi77 – 771Iron (heme axial ligand); via tele nitrogenCombined sources

GO - Molecular functioni

GO - Biological processi

  • regulation of transcription, DNA-templated Source: UniProtKB-KW
  • transcription, DNA-templated Source: CACAO
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotation

Keywords - Ligandi

DNA-bindingSAAS annotation, HemeCombined sources, Iron, Metal-binding

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-16458.

Names & Taxonomyi

Protein namesi
Submitted name:
CooA proteinImported
Gene namesi
Name:cooAImported
OrganismiRhodospirillum rubrumImported
Taxonomic identifieri1085 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodospirillalesRhodospirillaceaeRhodospirillum

Interactioni

Protein-protein interaction databases

STRINGi269796.Rru_A1431.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1FT9X-ray2.60A/B1-222[»]
ProteinModelPortaliP72322.
SMRiP72322. Positions 2-213.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP72322.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini133 – 20775HTH crp-type DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains HTH crp-type DNA-binding domain.SAAS annotation

Phylogenomic databases

eggNOGiENOG4105IP5. Bacteria.
ENOG410ZWAP. LUCA.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProiIPR018490. cNMP-bd-like.
IPR012318. HTH_CRP.
IPR014710. RmlC-like_jellyroll.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF13545. HTH_Crp_2. 1 hit.
[Graphical view]
SMARTiSM00419. HTH_CRP. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF51206. SSF51206. 1 hit.
PROSITEiPS51063. HTH_CRP_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P72322-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPRFNIANV LLSPDGETFF RGFRSKIHAK GSLVCTGEGD ENGVFVVVDG
60 70 80 90 100
RLRVYLVGEE REISLFYLTS GDMFCMHSGC LVEATERTEV RFADIRTFEQ
110 120 130 140 150
KLQTCPSMAW GLIAILGRAL TSCMRTIEDL MFHDIKQRIA GFFIDHANTT
160 170 180 190 200
GRQTQGGVIV SVDFTVEEIA NLIGSSRQTT STALNSLIKE GYISRQGRGH
210 220
YTIPNLVRLK AAADGDRDDD DD
Length:222
Mass (Da):24,635
Last modified:February 1, 1997 - v1
Checksum:iE568C084C201D55E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U65510 Genomic DNA. Translation: AAC45127.1.
PIRiA56276.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U65510 Genomic DNA. Translation: AAC45127.1.
PIRiA56276.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1FT9X-ray2.60A/B1-222[»]
ProteinModelPortaliP72322.
SMRiP72322. Positions 2-213.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi269796.Rru_A1431.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG4105IP5. Bacteria.
ENOG410ZWAP. LUCA.

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-16458.

Miscellaneous databases

EvolutionaryTraceiP72322.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
2.60.120.10. 1 hit.
InterProiIPR018490. cNMP-bd-like.
IPR012318. HTH_CRP.
IPR014710. RmlC-like_jellyroll.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF13545. HTH_Crp_2. 1 hit.
[Graphical view]
SMARTiSM00419. HTH_CRP. 1 hit.
[Graphical view]
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF51206. SSF51206. 1 hit.
PROSITEiPS51063. HTH_CRP_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Carbon monoxide-induced activation of gene expression in Rhodospirillum rubrum requires the product of cooA, a member of the cyclic AMP receptor protein family of transcriptional regulators."
    Shelver D., Kerby R.L., He Y., Roberts G.P.
    J. Bacteriol. 177:2157-2163(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: UR1Imported.
  2. "In vivo nickel insertion into the carbon monoxide dehydrogenase of Rhodospirillum rubrum: molecular and physiological characterization of cooCTJ."
    Kerby R.L., Ludden P.W., Roberts G.P.
    J. Bacteriol. 179:2259-2266(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: UR1Imported.
  3. Cited for: X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS) IN COMPLEX WITH HEME.

Entry informationi

Entry nameiP72322_RHORU
AccessioniPrimary (citable) accession number: P72322
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: May 11, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.