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Protein

Ornithine utilization regulator

Gene

oruR

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Probably activates the ArgJ gene that encodes ornithine acetyltransferase. Binds to its own promoter-operator region. Probably binds ornithine.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi257 – 27620H-T-H motifPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

  • ornithine catabolic process Source: PseudoCAP
  • regulation of transcription, DNA-templated Source: GO_Central
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ornithine utilization regulator
Gene namesi
Name:oruR
Ordered Locus Names:PA0831
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA0831.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 339339Ornithine utilization regulatorPRO_0000194543Add
BLAST

Proteomic databases

PaxDbiP72171.

Interactioni

Protein-protein interaction databases

STRINGi208964.PA0831.

Structurei

3D structure databases

ProteinModelPortaliP72171.
SMRiP72171. Positions 239-338.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 HTH araC/xylS-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4108ZX5. Bacteria.
ENOG4111NT4. LUCA.
InParanoidiP72171.
OMAiEFGATYS.
PhylomeDBiP72171.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR032687. AraC-type_N.
IPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR020449. Tscrpt_reg_HTH_AraC-type.
[Graphical view]
PfamiPF12625. Arabinose_bd. 1 hit.
PF12833. HTH_18. 1 hit.
[Graphical view]
PRINTSiPR00032. HTHARAC.
SMARTiSM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P72171-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKQPLNFTAE LVPVAYAEAL LDLVAEYGVS RQALFDAARV RPEVLDSPNG
60 70 80 90 100
RLSFLDFNQL TYSAQALCGE PALGLVLGQR LNVSAHGILG YAVLSSANLG
110 120 130 140 150
KAIQFALKYY RVLGLAYELE LVLDDGRAEL RAVESMPLGA ASVFAAEGLM
160 170 180 190 200
ATLYSIACFL VGEPLQDVRV GFAYPPPAHA RRYAEVFGVA AEFEQPWHWL
210 220 230 240 250
SMPSEYLERP MALANPATVQ MCEQQCEALL ATLDVQEGLL TRVRRLLLAR
260 270 280 290 300
PGDFPDLEQA ARELHTSGRS LRRHLSSLGT TYQQVLDDVR KRLALQYLTT
310 320 330
TQLPLYEIAL LLGFNDSSNF RRAFRKWTGK LPSDYREAP
Length:339
Mass (Da):37,610
Last modified:February 1, 1997 - v1
Checksum:iF1376ED624E97270
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U73506 Genomic DNA. Translation: AAB94774.1.
AE004091 Genomic DNA. Translation: AAG04220.1.
PIRiG83540.
RefSeqiNP_249522.1. NC_002516.2.
WP_003114220.1. NZ_ASJY01000127.1.

Genome annotation databases

EnsemblBacteriaiAAG04220; AAG04220; PA0831.
GeneIDi878384.
KEGGipae:PA0831.
PATRICi19835940. VBIPseAer58763_0862.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U73506 Genomic DNA. Translation: AAB94774.1.
AE004091 Genomic DNA. Translation: AAG04220.1.
PIRiG83540.
RefSeqiNP_249522.1. NC_002516.2.
WP_003114220.1. NZ_ASJY01000127.1.

3D structure databases

ProteinModelPortaliP72171.
SMRiP72171. Positions 239-338.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA0831.

Proteomic databases

PaxDbiP72171.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG04220; AAG04220; PA0831.
GeneIDi878384.
KEGGipae:PA0831.
PATRICi19835940. VBIPseAer58763_0862.

Organism-specific databases

PseudoCAPiPA0831.

Phylogenomic databases

eggNOGiENOG4108ZX5. Bacteria.
ENOG4111NT4. LUCA.
InParanoidiP72171.
OMAiEFGATYS.
PhylomeDBiP72171.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR032687. AraC-type_N.
IPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR020449. Tscrpt_reg_HTH_AraC-type.
[Graphical view]
PfamiPF12625. Arabinose_bd. 1 hit.
PF12833. HTH_18. 1 hit.
[Graphical view]
PRINTSiPR00032. HTHARAC.
SMARTiSM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiORUR_PSEAE
AccessioniPrimary (citable) accession number: P72171
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 19, 2001
Last sequence update: February 1, 1997
Last modified: September 7, 2016
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.