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Protein

B-type flagellin

Gene

fliC

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
B-type flagellin
Gene namesi
Name:fliC
Ordered Locus Names:PA1092
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA1092.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Bacterial flagellum, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 488488B-type flagellinPRO_0000182620Add
BLAST

Post-translational modificationi

Phosphorylated on tyrosine residue(s).1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP72151.
PRIDEiP72151.

Interactioni

Protein-protein interaction databases

DIPiDIP-59151N.
STRINGi208964.PA1092.

Structurei

3D structure databases

ProteinModelPortaliP72151.
SMRiP72151. Positions 2-488.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the bacterial flagellin family.Curated

Phylogenomic databases

eggNOGiENOG4105I03. Bacteria.
COG1344. LUCA.
HOGENOMiHOG000255144.
InParanoidiP72151.
KOiK02406.
OMAiRAHASVI.
OrthoDBiEOG6M9DVB.
PhylomeDBiP72151.

Family and domain databases

Gene3Di1.20.1330.10. 4 hits.
InterProiIPR001492. Flagellin.
IPR001029. Flagellin_D0/D1.
IPR010810. Flagellin_hook_IN_motif.
[Graphical view]
PfamiPF00700. Flagellin_C. 1 hit.
PF07196. Flagellin_IN. 1 hit.
PF00669. Flagellin_N. 1 hit.
[Graphical view]
PRINTSiPR00207. FLAGELLIN.

Sequencei

Sequence statusi: Complete.

P72151-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALTVNTNIA SLNTQRNLNA SSNDLNTSLQ RLTTGYRINS AKDDAAGLQI
60 70 80 90 100
SNRLSNQISG LNVATRNAND GISLAQTAEG ALQQSTNILQ RIRDLALQSA
110 120 130 140 150
NGSNSDADRA ALQKEVAAQQ AELTRISDTT TFGGRKLLDG SFGTTSFQVG
160 170 180 190 200
SNAYETIDIS LQNASASAIG SYQVGSNGAG TVASVAGTAT ASGIASGTVN
210 220 230 240 250
LVGGGQVKNI AIAAGDSAKA IAEKMDGAIP NLSARARTVF TADVSGVTGG
260 270 280 290 300
SLNFDVTVGS NTVSLAGVTS TQDLADQLNS NSSKLGITAS INDKGVLTIT
310 320 330 340 350
SATGENVKFG AQTGTATAGQ VAVKVQGSDG KFEAAAKNVV AAGTAATTTI
360 370 380 390 400
VTGYVQLNSP TAYSVSGTGT QASQVFGNAS AAQKSSVASV DISTADGAQN
410 420 430 440 450
AIAVVDNALA AIDAQRADLG AVQNRFKNTI DNLTNISENA TNARSRIKDT
460 470 480
DFAAETAALS KNQVLQQAGT AILAQANQLP QAVLSLLR
Length:488
Mass (Da):49,242
Last modified:December 8, 2000 - v2
Checksum:i7A2AEE09D3F58209
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti30 – 301Q → E in AAA99807 (Ref. 1) Curated
Sequence conflicti377 – 3771G → A in AAA99807 (Ref. 1) Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U54775 Genomic DNA. Translation: AAA99807.1.
AE004091 Genomic DNA. Translation: AAG04481.1.
PIRiE83507.
RefSeqiNP_249783.1. NC_002516.2.
WP_003112503.1. NZ_ASJY01000143.1.

Genome annotation databases

EnsemblBacteriaiAAG04481; AAG04481; PA1092.
GeneIDi882052.
KEGGipae:PA1092.
PATRICi19836490. VBIPseAer58763_1131.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U54775 Genomic DNA. Translation: AAA99807.1.
AE004091 Genomic DNA. Translation: AAG04481.1.
PIRiE83507.
RefSeqiNP_249783.1. NC_002516.2.
WP_003112503.1. NZ_ASJY01000143.1.

3D structure databases

ProteinModelPortaliP72151.
SMRiP72151. Positions 2-488.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-59151N.
STRINGi208964.PA1092.

Proteomic databases

PaxDbiP72151.
PRIDEiP72151.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG04481; AAG04481; PA1092.
GeneIDi882052.
KEGGipae:PA1092.
PATRICi19836490. VBIPseAer58763_1131.

Organism-specific databases

PseudoCAPiPA1092.

Phylogenomic databases

eggNOGiENOG4105I03. Bacteria.
COG1344. LUCA.
HOGENOMiHOG000255144.
InParanoidiP72151.
KOiK02406.
OMAiRAHASVI.
OrthoDBiEOG6M9DVB.
PhylomeDBiP72151.

Family and domain databases

Gene3Di1.20.1330.10. 4 hits.
InterProiIPR001492. Flagellin.
IPR001029. Flagellin_D0/D1.
IPR010810. Flagellin_hook_IN_motif.
[Graphical view]
PfamiPF00700. Flagellin_C. 1 hit.
PF07196. Flagellin_IN. 1 hit.
PF00669. Flagellin_N. 1 hit.
[Graphical view]
PRINTSiPR00207. FLAGELLIN.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Analysis of the type b flagellin gene of Pseudomonas aeruginosa PAO1."
    Wahl S.A., Baker N.R.
    Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.
  3. "Phosphorylated tyrosine in the flagellum filament protein of Pseudomonas aeruginosa."
    Kelly-Wintenberg K., Anderson T., Montie T.C.
    J. Bacteriol. 172:5135-5139(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION.
    Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228 and M-2.

Entry informationi

Entry nameiFLICB_PSEAE
AccessioniPrimary (citable) accession number: P72151
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: December 8, 2000
Last modified: December 9, 2015
This is version 102 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.