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P71913

- P71913_MYCTU

UniProt

P71913 - P71913_MYCTU

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Protein
Submitted name:

Ribokinase RbsK

Gene
rbsK, Rv2436, P425_02535, RVBD_2436
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi236 – 2361Magnesium; via carbonyl oxygenImported
Binding sitei237 – 2371ADP; via carbonyl oxygen
Metal bindingi238 – 2381Magnesium; via carbonyl oxygenImported
Binding sitei241 – 2411ADP; via amide nitrogen
Metal bindingi276 – 2761Magnesium; via carbonyl oxygenImported
Metal bindingi279 – 2791Magnesium; via carbonyl oxygenImported
Metal bindingi281 – 2811Magnesium; via carbonyl oxygenImported

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi212 – 2154ADP
Nucleotide bindingi270 – 2734ADP

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. nucleotide binding Source: UniProtKB-KW
  3. ribokinase activity Source: InterPro

GO - Biological processi

  1. D-ribose metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotationsImported, Transferase

Keywords - Ligandi

MagnesiumImported, Metal-bindingImported, Nucleotide-bindingImported

Enzyme and pathway databases

BioCyciMTBRV:RV2436-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Ribokinase RbsKImported
Gene namesi
Name:rbsKImported
Ordered Locus Names:Rv2436Imported
ORF Names:P425_02535Imported, RVBD_2436Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
ProteomesiUP000001584: Chromosome, UP000003123: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv2436.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3GO6X-ray1.98A/B2-304[»]
3GO7X-ray2.50A/B2-304[»]

Family & Domainsi

Phylogenomic databases

KOiK00852.
OMAiFEDRIEP.

Family and domain databases

Gene3Di3.40.1190.20. 1 hit.
InterProiIPR011611. PfkB_dom.
IPR002139. Ribokinase.
IPR029056. Ribokinase-like.
[Graphical view]
PfamiPF00294. PfkB. 1 hit.
[Graphical view]
PRINTSiPR00990. RIBOKINASE.
SUPFAMiSSF53613. SSF53613. 1 hit.

Sequencei

Sequence statusi: Complete.

P71913-1 [UniParc]FASTAAdd to Basket

« Hide

MANASETNVG PMAPRVCVVG SVNMDLTFVV DALPRPGETV LAASLTRTPG    50
GKGANQAVAA ARAGAQVQFS GAFGDDPAAA QLRAHLRANA VGLDRTVTVP 100
GPSGTAIIVV DASAENTVLV APGANAHLTP VPSAVANCDV LLTQLEIPVA 150
TALAAARAAQ SADAVVMVNA SPAGQDRSSL QDLAAIADVV IANEHEANDW 200
PSPPTHFVIT LGVRGARYVG ADGVFEVPAP TVTPVDTAGA GDVFAGVLAA 250
NWPRNPGSPA ERLRALRRAC AAGALATLVS GVGDCAPAAA AIDAALRANR 300
HNGS 304
Length:304
Mass (Da):30,280
Last modified:February 1, 1997 - v1
Checksum:iD1990AADD9F1BA7A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003248 Genomic DNA. Translation: AFN50401.1.
AL123456 Genomic DNA. Translation: CCP45228.1.
JLDD01000032 Genomic DNA. Translation: KBJ30762.1.
RefSeqiNP_216952.1. NC_000962.3.
YP_006515872.1. NC_018143.2.

Genome annotation databases

EnsemblBacteriaiAFN50401; AFN50401; RVBD_2436.
CCP45228; CCP45228; Rv2436.
GeneIDi13319145.
885671.
KEGGimtu:Rv2436.
mtv:RVBD_2436.
PATRICi18154013. VBIMycTub87468_2730.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003248 Genomic DNA. Translation: AFN50401.1 .
AL123456 Genomic DNA. Translation: CCP45228.1 .
JLDD01000032 Genomic DNA. Translation: KBJ30762.1 .
RefSeqi NP_216952.1. NC_000962.3.
YP_006515872.1. NC_018143.2.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3GO6 X-ray 1.98 A/B 2-304 [» ]
3GO7 X-ray 2.50 A/B 2-304 [» ]
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 83332.Rv2436.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AFN50401 ; AFN50401 ; RVBD_2436 .
CCP45228 ; CCP45228 ; Rv2436 .
GeneIDi 13319145.
885671.
KEGGi mtu:Rv2436.
mtv:RVBD_2436.
PATRICi 18154013. VBIMycTub87468_2730.

Phylogenomic databases

KOi K00852.
OMAi FEDRIEP.

Enzyme and pathway databases

BioCyci MTBRV:RV2436-MONOMER.

Family and domain databases

Gene3Di 3.40.1190.20. 1 hit.
InterProi IPR011611. PfkB_dom.
IPR002139. Ribokinase.
IPR029056. Ribokinase-like.
[Graphical view ]
Pfami PF00294. PfkB. 1 hit.
[Graphical view ]
PRINTSi PR00990. RIBOKINASE.
SUPFAMi SSF53613. SSF53613. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25618 / H37Rv and H37RvImported.
  2. "Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv."
    Camus J.C., Pryor M.J., Medigue C., Cole S.T.
    Microbiology 148:2967-2973(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H37RvImported.
  3. "Crystal structure and biochemical characterization of M.tuberculosis ribokinase (Rv2436)."
    Masters E.I., Sun Y., Wang Y., Parker W.B., Li R
    Submitted (MAR-2009) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.98 ANGSTROMS) OF 2-304 IN COMPLEX WITH ADP AND MAGNESIUM.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H37RvImported.
  5. Lew J.M.
    Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H37RvImported.
  6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25618 / H37Rv.
  7. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H37RvImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: H37RvImported.

Entry informationi

Entry nameiP71913_MYCTU
AccessioniPrimary (citable) accession number: P71913
Secondary accession number(s): I6X491
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: September 3, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteome

External Data

Dasty 3

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