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Protein
Submitted name:

Probable C4-dicarboxylate-transport transmembrane protein DctA

Gene

dctA

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Biological processTransportSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Probable C4-dicarboxylate-transport transmembrane protein DctAImported
Gene namesi
Name:dctAImported
Ordered Locus Names:Rv2443Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome

Organism-specific databases

TubercuListiRv2443

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei25 – 45HelicalSequence analysisAdd BLAST21
Transmembranei57 – 81HelicalSequence analysisAdd BLAST25
Transmembranei93 – 116HelicalSequence analysisAdd BLAST24
Transmembranei166 – 184HelicalSequence analysisAdd BLAST19
Transmembranei204 – 229HelicalSequence analysisAdd BLAST26
Transmembranei235 – 257HelicalSequence analysisAdd BLAST23
Transmembranei347 – 372HelicalSequence analysisAdd BLAST26

GO - Cellular componenti

  • extracellular region Source: MTBBASE
  • integral component of membrane Source: UniProtKB-KW

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiP71906

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv2443

Structurei

3D structure databases

SMRiP71906
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. [View classification]SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiCOG1301 LUCA
HOGENOMiHOG000208775
KOiK11103
OMAiYLYIAVI

Family and domain databases

Gene3Di1.10.3860.10, 1 hit
InterProiView protein in InterPro
IPR001991 Na-dicarboxylate_symporter
IPR036458 Na:dicarbo_symporter_sf
PfamiView protein in Pfam
PF00375 SDF, 1 hit
SUPFAMiSSF118215 SSF118215, 1 hit

Sequencei

Sequence statusi: Complete.

P71906-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAPLDRAPV TDLPANNKGR DRTHWLYLAV IFAVIAGVIV GLTAPSTGKS
60 70 80 90 100
LTVLGTVFVN LIKMMIAPVI FCTIVLGIGS VRKAAAVGKV GGLALAYFLT
110 120 130 140 150
MSSVALGIGL IVGNLLSPGR DLHLRPGAVG SGAALAGQAA ESHGIAGFIQ
160 170 180 190 200
QIIPRSLPSA LTEGNVLQVL LVALLVGFAV QGLGPAGESI LRAVENLQKL
210 220 230 240 250
VFKVLVMVLW LAPIGAFGAI ANIVATTGFN AVTNLLLLMA GFYLTCVVFV
260 270 280 290 300
FGVLGVLLRI VSGLSIFRLL RYLAREYLLI FATSSSEVVL PRLITKMKHL
310 320 330 340 350
GVQSSTVGVV VPTGYSFNLD GTAIYLTMAS LFIADAMGHR LTWGEQIALL
360 370 380 390 400
AFMIIASKGA AGVSGAGLAT LAGGLQAHRP ELLDGVGLIV GIDRFMSEAR
410 420 430 440 450
SLTNFSGNAV ATILVASWTK TIDLSKADEV LRGRDPFDES TMVDPHDEEP
460 470 480 490
PAATPHGGGV PTNPALCDFE QVSLGGLVGR PAGPQRADVD G
Length:491
Mass (Da):50,988
Last modified:February 1, 1997 - v1
Checksum:iBA9F676DBB14E353
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL123456 Genomic DNA Translation: CCP45236.1
RefSeqiNP_216959.1, NC_000962.3
WP_003412582.1, NZ_KK339370.1

Genome annotation databases

EnsemblBacteriaiAIR15210; AIR15210; LH57_13360
CCP45236; CCP45236; Rv2443
GeneIDi885745
KEGGimtu:Rv2443
mtv:RVBD_2443

Similar proteinsi

Entry informationi

Entry nameiP71906_MYCTU
AccessioniPrimary (citable) accession number: P71906
Secondary accession number(s): F2GHM5, I6XEB9, Q7D749
Entry historyiIntegrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: March 28, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health