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P71571 (Y938_MYCTU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 98. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative DNA ligase-like protein Rv0938/MT0965
Gene names
Ordered Locus Names:Rv0938, MT0965
ORF Names:MTCY08D9.01c, MTCY10D7.36c
OrganismMycobacterium tuberculosis [Reference proteome] [HAMAP]
Taxonomic identifier1773 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex

Protein attributes

Sequence length759 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the ATP-dependent DNA ligase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 759759Putative DNA ligase-like protein Rv0938/MT0965
PRO_0000059627

Sites

Active site4811N6-AMP-lysine intermediate By similarity

Experimental info

Sequence conflict3441C → R in AAK45212. Ref.2

Secondary structure

...................................................................................................... 759
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P71571 [UniParc].

Last modified May 30, 2000. Version 2.
Checksum: 81BD49222EE09E36

FASTA75983,572
        10         20         30         40         50         60 
MGSASEQRVT LTNADKVLYP ATGTTKSDIF DYYAGVAEVM LGHIAGRPAT RKRWPNGVDQ 

        70         80         90        100        110        120 
PAFFEKQLAL SAPPWLSRAT VAHRSGTTTY PIIDSATGLA WIAQQAALEV HVPQWRFVAE 

       130        140        150        160        170        180 
PGSGELNPGP ATRLVFDLDP GEGVMMAQLA EVARAVRDLL ADIGLVTFPV TSGSKGLHLY 

       190        200        210        220        230        240 
TPLDEPVSSR GATVLAKRVA QRLEQAMPAL VTSTMTKSLR AGKVFVDWSQ NSGSKTTIAP 

       250        260        270        280        290        300 
YSLRGRTHPT VAAPRTWAEL DDPALRQLSY DEVLTRIARD GDLLERLDAD APVADRLTRY 

       310        320        330        340        350        360 
RRMRDASKTP EPIPTAKPVT GDGNTFVIQE HHARRPHYDF RLECDGVLVS WAVPKNLPDN 

       370        380        390        400        410        420 
TSVNHLAIHT EDHPLEYATF EGAIPSGEYG AGKVIIWDSG TYDTEKFHDD PHTGEVIVNL 

       430        440        450        460        470        480 
HGGRISGRYA LIRTNGDRWL AHRLKNQKDQ KVFEFDNLAP MLATHGTVAG LKASQWAFEG 

       490        500        510        520        530        540 
KWDGYRLLVE ADHGAVRLRS RSGRDVTAEY PQLRALAEDL ADHHVVLDGE AVVLDSSGVP 

       550        560        570        580        590        600 
SFSQMQNRGR DTRVEFWAFD LLYLDGRALL GTRYQDRRKL LETLANATSL TVPELLPGDG 

       610        620        630        640        650        660 
AQAFACSRKH GWEGVIAKRR DSRYQPGRRC ASWVKDKHWN TQEVVIGGWR AGEGGRSSGV 

       670        680        690        700        710        720 
GSLLMGIPGP GGLQFAGRVG TGLSERELAN LKEMLAPLHT DESPFDVPLP ARDAKGITYV 

       730        740        750 
KPALVAEVRY SEWTPEGRLR QSSWRGLRPD KKPSEVVRE 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000516 Genomic DNA. Translation: AAK45212.1.
AL123456 Genomic DNA. Translation: CCP43686.1.
PIRB70585.
RefSeqNP_215453.1. NC_000962.3.
NP_335398.1. NC_002755.2.
YP_006514294.1. NC_018143.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1VS0X-ray2.40A/B452-759[»]
2IRUX-ray1.65A/B1-300[»]
2IRXX-ray1.80A1-300[»]
2IRYX-ray1.78A/B1-300[»]
2R9LX-ray2.40A/B1-300[»]
3PKYX-ray3.10A/B1-300[»]
ProteinModelPortalP71571.
SMRP71571. Positions 3-288, 326-434, 453-759.
ModBaseSearch...

Protein-protein interaction databases

STRING83332.Rv0938.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAK45212; AAK45212; MT0965.
GeneID13318846.
885561.
926354.
KEGGmtc:MT0965.
mtu:Rv0938.
PATRIC18123864. VBIMycTub22151_1055.

Organism-specific databases

TubercuListRv0938.

Phylogenomic databases

eggNOGCOG3285.
HOGENOMHOG000222509.
KOK01971.
OMASGSKGIH.
ProtClustDBPRK09632.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
InterProIPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR014146. DNA_pol_LigD_ligase_dom.
IPR002755. DNA_primase_S.
IPR014144. LigD_PE_domain.
IPR014145. LigD_pol.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF01896. DNA_primase_S. 1 hit.
PF13298. LigD_N. 1 hit.
[Graphical view]
SUPFAMSSF50249. Nucleic_acid_OB. 1 hit.
TIGRFAMsTIGR02777. LigD_PE_dom. 1 hit.
TIGR02778. ligD_pol. 1 hit.
TIGR02779. NHEJ_ligase_lig. 1 hit.
PROSITEPS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP71571.

Entry information

Entry nameY938_MYCTU
AccessionPrimary (citable) accession number: P71571
Secondary accession number(s): L0T5C5, O05865
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: May 30, 2000
Last modified: May 29, 2013
This is version 98 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh

Mycobacterium tuberculosis strains ATCC 25618 / H37Rv and CDC 1551 / Oshkosh: entries and gene names

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families