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P71405

- CYSE_HELPY

UniProt

P71405 - CYSE_HELPY

Protein

Serine acetyltransferase

Gene

cysE

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 2 (01 Nov 1997)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Acetyl-CoA + L-serine = CoA + O-acetyl-L-serine.

    Pathwayi

    GO - Molecular functioni

    1. serine O-acetyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cysteine biosynthetic process from serine Source: InterPro

    Keywords - Molecular functioni

    Acyltransferase, Transferase

    Keywords - Biological processi

    Amino-acid biosynthesis, Cysteine biosynthesis

    Enzyme and pathway databases

    BioCyciHPY:HP1210-MONOMER.
    UniPathwayiUPA00136; UER00199.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Serine acetyltransferase (EC:2.3.1.30)
    Short name:
    SAT
    Gene namesi
    Name:cysE
    Ordered Locus Names:HP_1210
    OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
    Taxonomic identifieri85962 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
    ProteomesiUP000000429: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 171171Serine acetyltransferasePRO_0000068675Add
    BLAST

    Proteomic databases

    PRIDEiP71405.

    Interactioni

    Protein-protein interaction databases

    STRINGi85962.HP1210.

    Structurei

    3D structure databases

    ProteinModelPortaliP71405.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiCOG1045.
    KOiK00640.
    OMAiDVILYHG.
    OrthoDBiEOG6HMXK6.

    Family and domain databases

    InterProiIPR001451. Hexapep_transf.
    IPR018357. Hexapep_transf_CS.
    IPR005881. Ser_O-AcTrfase.
    IPR011004. Trimer_LpxA-like.
    [Graphical view]
    PfamiPF00132. Hexapep. 2 hits.
    [Graphical view]
    PIRSFiPIRSF000441. CysE. 1 hit.
    SUPFAMiSSF51161. SSF51161. 1 hit.
    TIGRFAMsiTIGR01172. cysE. 1 hit.
    PROSITEiPS00101. HEXAPEP_TRANSFERASES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P71405-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLDLSYSLER VLQEDPAARN KWEVLLLYPG IHALLCYRLA HALHKRRFYF    50
    IARALSQLAR FITGIEIHPG AKIGRGLFID HGMGVVIGET TEIGDDVTIY 100
    HGVTLGGTGK FKGKRHPTLG NRVVVGAGAK VLGAICVGDD VKIGANAVVL 150
    SDLPTGSTAV GSKAKTITKD R 171
    Length:171
    Mass (Da):18,342
    Last modified:November 1, 1997 - v2
    Checksum:i28646D539C2250C3
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti5 – 51S → F in strain: 60190.
    Natural varianti110 – 1101K → R in strain: 60190.
    Natural varianti162 – 1621S → T in strain: 60190.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U43917 Genomic DNA. Translation: AAB07027.1.
    AE000511 Genomic DNA. Translation: AAD08254.1.
    PIRiB64671.
    RefSeqiNP_208002.1. NC_000915.1.
    YP_006935131.1. NC_018939.1.

    Genome annotation databases

    EnsemblBacteriaiAAD08254; AAD08254; HP_1210.
    GeneIDi13870416.
    898797.
    KEGGiheo:C694_06265.
    hpy:HP1210.
    PATRICi20593791. VBIHelPyl33062_1268.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U43917 Genomic DNA. Translation: AAB07027.1 .
    AE000511 Genomic DNA. Translation: AAD08254.1 .
    PIRi B64671.
    RefSeqi NP_208002.1. NC_000915.1.
    YP_006935131.1. NC_018939.1.

    3D structure databases

    ProteinModelPortali P71405.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 85962.HP1210.

    Proteomic databases

    PRIDEi P71405.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAD08254 ; AAD08254 ; HP_1210 .
    GeneIDi 13870416.
    898797.
    KEGGi heo:C694_06265.
    hpy:HP1210.
    PATRICi 20593791. VBIHelPyl33062_1268.

    Phylogenomic databases

    eggNOGi COG1045.
    KOi K00640.
    OMAi DVILYHG.
    OrthoDBi EOG6HMXK6.

    Enzyme and pathway databases

    UniPathwayi UPA00136 ; UER00199 .
    BioCyci HPY:HP1210-MONOMER.

    Family and domain databases

    InterProi IPR001451. Hexapep_transf.
    IPR018357. Hexapep_transf_CS.
    IPR005881. Ser_O-AcTrfase.
    IPR011004. Trimer_LpxA-like.
    [Graphical view ]
    Pfami PF00132. Hexapep. 2 hits.
    [Graphical view ]
    PIRSFi PIRSF000441. CysE. 1 hit.
    SUPFAMi SSF51161. SSF51161. 1 hit.
    TIGRFAMsi TIGR01172. cysE. 1 hit.
    PROSITEi PS00101. HEXAPEP_TRANSFERASES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Expression of a novel ulcer-associated gene, iceA, by H. pylori following contact with gastric epithelium."
      Peek R.M. Jr., Thompson S.A., Atherton J.C., Blaser M.J., Miller G.G.
      Submitted (SEP-1996) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 49503 / 60190.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700392 / 26695.

    Entry informationi

    Entry nameiCYSE_HELPY
    AccessioniPrimary (citable) accession number: P71405
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1997
    Last modified: October 1, 2014
    This is version 90 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Helicobacter pylori
      Helicobacter pylori (strain 26695): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3