Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Serine acetyltransferase

Gene

cysE

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Acetyl-CoA + L-serine = CoA + O-acetyl-L-serine.

Pathwayi: L-cysteine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes L-cysteine from L-serine.
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. Serine acetyltransferase (cysE)
  2. Cysteine synthase (cysM)
This subpathway is part of the pathway L-cysteine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-cysteine from L-serine, the pathway L-cysteine biosynthesis and in Amino-acid biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase
Biological processAmino-acid biosynthesis, Cysteine biosynthesis

Enzyme and pathway databases

BioCyciHPY:HP1210-MONOMER
UniPathwayiUPA00136; UER00199

Names & Taxonomyi

Protein namesi
Recommended name:
Serine acetyltransferase (EC:2.3.1.30)
Short name:
SAT
Gene namesi
Name:cysE
Ordered Locus Names:HP_1210
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
Proteomesi
  • UP000000429 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000686751 – 171Serine acetyltransferaseAdd BLAST171

Proteomic databases

PaxDbiP71405

Interactioni

Protein-protein interaction databases

STRINGi85962.HP1210

Structurei

3D structure databases

ProteinModelPortaliP71405
SMRiP71405
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4105D7W Bacteria
COG1045 LUCA
KOiK00640
OMAiDGCTIYQ

Family and domain databases

InterProiView protein in InterPro
IPR001451 Hexapep
IPR018357 Hexapep_transf_CS
IPR005881 Ser_O-AcTrfase
IPR011004 Trimer_LpxA-like_sf
PfamiView protein in Pfam
PF00132 Hexapep, 2 hits
PIRSFiPIRSF000441 CysE, 1 hit
SUPFAMiSSF51161 SSF51161, 1 hit
TIGRFAMsiTIGR01172 cysE, 1 hit
PROSITEiView protein in PROSITE
PS00101 HEXAPEP_TRANSFERASES, 1 hit

Sequencei

Sequence statusi: Complete.

P71405-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLDLSYSLER VLQEDPAARN KWEVLLLYPG IHALLCYRLA HALHKRRFYF
60 70 80 90 100
IARALSQLAR FITGIEIHPG AKIGRGLFID HGMGVVIGET TEIGDDVTIY
110 120 130 140 150
HGVTLGGTGK FKGKRHPTLG NRVVVGAGAK VLGAICVGDD VKIGANAVVL
160 170
SDLPTGSTAV GSKAKTITKD R
Length:171
Mass (Da):18,342
Last modified:November 1, 1997 - v2
Checksum:i28646D539C2250C3
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti5S → F in strain: 60190. 1
Natural varianti110K → R in strain: 60190. 1
Natural varianti162S → T in strain: 60190. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U43917 Genomic DNA Translation: AAB07027.1
AE000511 Genomic DNA Translation: AAD08254.1
PIRiB64671
RefSeqiNP_208002.1, NC_000915.1
WP_000886346.1, NC_018939.1

Genome annotation databases

EnsemblBacteriaiAAD08254; AAD08254; HP_1210
GeneIDi898797
KEGGiheo:C694_06265
hpy:HP1210
PATRICifig|85962.47.peg.1301

Similar proteinsi

Entry informationi

Entry nameiCYSE_HELPY
AccessioniPrimary (citable) accession number: P71405
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: March 28, 2018
This is version 104 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health