Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Chemotaxis protein CheY homolog

Gene

cheY

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheY seems to regulate the clockwise (CW) rotation (By similarity).By similarity

Cofactori

Mg2+By similarityNote: Binds 1 Mg2+ ion per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi7 – 71MagnesiumBy similarity
Metal bindingi8 – 81MagnesiumBy similarity
Metal bindingi53 – 531MagnesiumBy similarity
Metal bindingi55 – 551Magnesium; via carbonyl oxygenBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Chemotaxis, Flagellar rotation, Two-component regulatory system

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

BioCyciHPY:HP1067-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Chemotaxis protein CheY homolog
Gene namesi
Name:cheY
Ordered Locus Names:HP_1067
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
Proteomesi
  • UP000000429 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 124124Chemotaxis protein CheY homologPRO_0000081050Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei53 – 5314-aspartylphosphatePROSITE-ProRule annotation

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP71403.
PRIDEiP71403.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
HP_0392O251533EBI-6409045,EBI-6410665

Protein-protein interaction databases

DIPiDIP-3256N.
IntActiP71403. 4 interactions.
MINTiMINT-160671.
STRINGi85962.HP1067.

Structurei

Secondary structure

1
124
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi3 – 64Combined sources
Helixi10 – 2213Combined sources
Beta strandi28 – 336Combined sources
Helixi34 – 4310Combined sources
Beta strandi49 – 524Combined sources
Beta strandi57 – 593Combined sources
Helixi61 – 699Combined sources
Beta strandi74 – 763Combined sources
Beta strandi79 – 846Combined sources
Helixi88 – 9710Combined sources
Beta strandi101 – 1055Combined sources
Helixi109 – 12012Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3GWGX-ray1.80A1-124[»]
3H1EX-ray2.40A1-124[»]
3H1FX-ray2.20A1-124[»]
3H1GX-ray1.70A1-124[»]
ProteinModelPortaliP71403.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP71403.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 120119Response regulatoryPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 response regulatory domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4108VYJ. Bacteria.
COG0784. LUCA.
KOiK03413.
OMAiTNTHEAD.

Family and domain databases

InterProiIPR011006. CheY-like_superfamily.
IPR001789. Sig_transdc_resp-reg_receiver.
[Graphical view]
PfamiPF00072. Response_reg. 1 hit.
[Graphical view]
SMARTiSM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF52172. SSF52172. 1 hit.
PROSITEiPS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P71403-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLLVVDDSS TMRRIIKNTL SRLGYEDVLE AEHGVEAWEK LDANADTKVL
60 70 80 90 100
ITDWNMPEMN GLDLVKKVRS DSRFKEIPII MITTEGGKAE VITALKAGVN
110 120
NYIVKPFTPQ VLKEKLEVVL GTND
Length:124
Mass (Da):13,915
Last modified:November 1, 1997 - v2
Checksum:iF2B40BC0C04FCBFA
GO

Sequence cautioni

The sequence CAA57487 differs from that shown. Reason: Erroneous initiation. Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti122 – 1221T → A in strain: NCTC 11637 and NCTC 11638.

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X81897 Genomic DNA. Translation: CAA57487.1. Different initiation.
U97567 Genomic DNA. Translation: AAB66375.1.
AE000511 Genomic DNA. Translation: AAD08113.1.
AF021090 Genomic DNA. Translation: AAD01682.1.
PIRiC64653.
RefSeqiNP_207858.1. NC_000915.1.
WP_000772151.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD08113; AAD08113; HP_1067.
GeneIDi899603.
KEGGiheo:C694_05515.
hpy:HP1067.
PATRICi20593473. VBIHelPyl33062_1116.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X81897 Genomic DNA. Translation: CAA57487.1. Different initiation.
U97567 Genomic DNA. Translation: AAB66375.1.
AE000511 Genomic DNA. Translation: AAD08113.1.
AF021090 Genomic DNA. Translation: AAD01682.1.
PIRiC64653.
RefSeqiNP_207858.1. NC_000915.1.
WP_000772151.1. NC_018939.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3GWGX-ray1.80A1-124[»]
3H1EX-ray2.40A1-124[»]
3H1FX-ray2.20A1-124[»]
3H1GX-ray1.70A1-124[»]
ProteinModelPortaliP71403.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-3256N.
IntActiP71403. 4 interactions.
MINTiMINT-160671.
STRINGi85962.HP1067.

Proteomic databases

PaxDbiP71403.
PRIDEiP71403.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD08113; AAD08113; HP_1067.
GeneIDi899603.
KEGGiheo:C694_05515.
hpy:HP1067.
PATRICi20593473. VBIHelPyl33062_1116.

Phylogenomic databases

eggNOGiENOG4108VYJ. Bacteria.
COG0784. LUCA.
KOiK03413.
OMAiTNTHEAD.

Enzyme and pathway databases

BioCyciHPY:HP1067-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP71403.

Family and domain databases

InterProiIPR011006. CheY-like_superfamily.
IPR001789. Sig_transdc_resp-reg_receiver.
[Graphical view]
PfamiPF00072. Response_reg. 1 hit.
[Graphical view]
SMARTiSM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF52172. SSF52172. 1 hit.
PROSITEiPS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCHEY_HELPY
AccessioniPrimary (citable) accession number: P71403
Secondary accession number(s): O07677
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: September 7, 2016
This is version 108 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.