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Protein

Uncharacterized ABC transporter ATP-binding protein HI_0663

Gene

HI_0663

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi347 – 3548ATPPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATPase activity, coupled to transmembrane movement of substances Source: InterPro
  2. ATP binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized ABC transporter ATP-binding protein HI_0663
Gene namesi
Ordered Locus Names:HI_0663
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
ProteomesiUP000000579: Chromosome

Subcellular locationi

Cell inner membrane Curated; Multi-pass membrane protein PROSITE-ProRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei2 – 2221HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei32 – 5221HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei108 – 12821HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei138 – 16023HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei168 – 18821HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei223 – 24321HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei249 – 26921HelicalPROSITE-ProRule annotationAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 560560Uncharacterized ABC transporter ATP-binding protein HI_0663PRO_0000093201Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi71421.HI0663m.

Structurei

3D structure databases

ProteinModelPortaliP71355.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 281281ABC transmembrane type-1PROSITE-ProRule annotationAdd
BLAST
Domaini314 – 547234ABC transporterPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ABC transporter superfamily.Curated
Contains 1 ABC transmembrane type-1 domain.PROSITE-ProRule annotation
Contains 1 ABC transporter domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG4988.
KOiK06148.
OMAiIYQDDAY.
OrthoDBiEOG6T7N3V.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00664. ABC_membrane. 1 hit.
PF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF90123. SSF90123. 1 hit.
PROSITEiPS50929. ABC_TM1F. 1 hit.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P71355-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLWNWVALVG GIISAVVFSY ILQAAYFHEL SLLSAVILGI VLIAALALRA
60 70 80 90 100
FAGKKSVQAS YFASTKVKHE LRSLIYRKLA SMPLNQVNQQ STSSIIQVAS
110 120 130 140 150
EGVEQLEIYF GRYLPQLFYS LLAPLTLFAF LIFFSFKTAI ILLICVPLIP
160 170 180 190 200
MSIIAVNKIA KKLLAKYWSI YVGLGSSFLD NLQGLITLKI YQDDAYKAKA
210 220 230 240 250
MDKEAEHFRK ITMKVLTMQL NSVSLMDLLA YGGAAIGILT ALLQFQNAQL
260 270 280 290 300
SVLGVILFIL LSSEFFIPLR LLGSFFHVAM NGKAASDKIF TLLDTPVETQ
310 320 330 340 350
QSAVDFEAKN NVQVEIKDLH FSYSEEKPAI TGLNLSILPN QLSVFVGKSG
360 370 380 390 400
CGKSTLVSLL MGFNKAQQGE ILFNGQNALN IDRTSFYQKV SLVSHSSYVF
410 420 430 440 450
KGTLRENMTM AKIDATDEQI YACLEQVNLA QFVRDNGGLD MQLLSRGANL
460 470 480 490 500
SGGQIQRLAL ARALLHNAEL YIFDEATSNI DVESEEIILQ FIQQFKQQKT
510 520 530 540 550
IVMISHRLAN AVNADCINVL DQGKLIEQGT HKELMEKQGA YAEMFQQQKD
560
LEQIREVANA
Length:560
Mass (Da):62,197
Last modified:February 1, 1997 - v1
Checksum:i65ADC0D0BC1347DE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC22320.1.
RefSeqiNP_438822.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC22320; AAC22320; HI_0663.
GeneIDi949702.
KEGGihin:HI0663m.
PATRICi20189941. VBIHaeInf48452_0692.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L42023 Genomic DNA. Translation: AAC22320.1.
RefSeqiNP_438822.1. NC_000907.1.

3D structure databases

ProteinModelPortaliP71355.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi71421.HI0663m.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC22320; AAC22320; HI_0663.
GeneIDi949702.
KEGGihin:HI0663m.
PATRICi20189941. VBIHaeInf48452_0692.

Phylogenomic databases

eggNOGiCOG4988.
KOiK06148.
OMAiIYQDDAY.
OrthoDBiEOG6T7N3V.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00664. ABC_membrane. 1 hit.
PF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF90123. SSF90123. 1 hit.
PROSITEiPS50929. ABC_TM1F. 1 hit.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Entry informationi

Entry nameiY663_HAEIN
AccessioniPrimary (citable) accession number: P71355
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: February 1, 1997
Last modified: January 7, 2015
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.