P71355 (Y663_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized ABC transporter ATP-binding protein HI_0663

Gene names

Ordered Locus Names:

HI_0663

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]

Taxonomic identifier

71421 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › Haemophilus influenzae

Protein attributes

Sequence length	560 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Cell inner membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the ABC transporter superfamily. Contains 1 ABC transmembrane type-1 domain. Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	ATP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity, coupled to transmembrane movement of substances Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 560	560	Uncharacterized ABC transporter ATP-binding protein HI_0663		PRO_0000093201
Regions
	Transmembrane	2 – 22	21	Helical; Potential
	Transmembrane	32 – 52	21	Helical; Potential
	Transmembrane	108 – 128	21	Helical; Potential
	Transmembrane	138 – 160	23	Helical; Potential
	Transmembrane	168 – 188	21	Helical; Potential
	Transmembrane	223 – 243	21	Helical; Potential
	Transmembrane	249 – 269	21	Helical; Potential
	Domain	1 – 281	281	ABC transmembrane type-1
	Domain	314 – 547	234	ABC transporter
	Nucleotide binding	347 – 354	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	P71355 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 65ADC0D0BC1347DE	FASTA	560	62,197
	10 20 30 40 50 60 MLWNWVALVG GIISAVVFSY ILQAAYFHEL SLLSAVILGI VLIAALALRA FAGKKSVQAS 70 80 90 100 110 120 YFASTKVKHE LRSLIYRKLA SMPLNQVNQQ STSSIIQVAS EGVEQLEIYF GRYLPQLFYS 130 140 150 160 170 180 LLAPLTLFAF LIFFSFKTAI ILLICVPLIP MSIIAVNKIA KKLLAKYWSI YVGLGSSFLD 190 200 210 220 230 240 NLQGLITLKI YQDDAYKAKA MDKEAEHFRK ITMKVLTMQL NSVSLMDLLA YGGAAIGILT 250 260 270 280 290 300 ALLQFQNAQL SVLGVILFIL LSSEFFIPLR LLGSFFHVAM NGKAASDKIF TLLDTPVETQ 310 320 330 340 350 360 QSAVDFEAKN NVQVEIKDLH FSYSEEKPAI TGLNLSILPN QLSVFVGKSG CGKSTLVSLL 370 380 390 400 410 420 MGFNKAQQGE ILFNGQNALN IDRTSFYQKV SLVSHSSYVF KGTLRENMTM AKIDATDEQI 430 440 450 460 470 480 YACLEQVNLA QFVRDNGGLD MQLLSRGANL SGGQIQRLAL ARALLHNAEL YIFDEATSNI 490 500 510 520 530 540 DVESEEIILQ FIQQFKQQKT IVMISHRLAN AVNADCINVL DQGKLIEQGT HKELMEKQGA 550 560 YAEMFQQQKD LEQIREVANA

References

[1]

"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L42023 Genomic DNA. Translation: AAC22320.1.
RefSeq	NP_438822.1. NC_000907.1.
3D structure databases
ProteinModelPortal	P71355.
ModBase	Search...
Protein-protein interaction databases
STRING	71421.HI0663m.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC22320; AAC22320; HI_0663.
GeneID	949702.
KEGG	hin:HI0663m.
PATRIC	20189941. VBIHaeInf48452_0692.
Phylogenomic databases
eggNOG	COG4988.
KO	K06148.
OMA	ENEASDI.
ProtClustDB	CLSK789779.
Family and domain databases
InterPro	IPR003593. AAA+_ATPase. IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR017940. ABC_transporter_type1. IPR001140. ABC_transptr_TM_dom. IPR011527. ABC_transptrTM_dom_typ1. IPR027417. P-loop_NTPase. [Graphical view]
Pfam	PF00664. ABC_membrane. 1 hit. PF00005. ABC_tran. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
SUPFAM	SSF90123. ABC_TM_1. 1 hit. SSF52540. SSF52540. 1 hit.
PROSITE	PS50929. ABC_TM1F. 1 hit. PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y663_HAEIN

Accession

Primary (citable) accession number: P71355

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	February 1, 1997
Last modified:	May 29, 2013
This is version 93 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program